Over-expression Lysates

Proteins

Over-expression Lysates

Human

CIAP1

CULLIN 5

FBXO4

NEDD4

SMURF1

TRAF6

TRIM37

VON HIPPEL LINDAU

WWP2

WB

HEK293T

C-Myc/DDK

Druggable Genome

WB

Transcription Factors

Pathways in cancer

Metabolic pathways

Focal adhesion

MAPK signaling pathway

Regulation of actin cytoskeleton

Cytokine-cytokine receptor interaction

Endocytosis

Prostate cancer

Wnt signaling pathway

Chemokine signaling pathway

Chronic myeloid leukemia

Endometrial cancer

Insulin signaling pathway

Cell cycle

Colorectal cancer

Neuroactive ligand-receptor interaction

Small cell lung cancer

Adherens junction

Bladder cancer

Melanoma

Neurotrophin signaling pathway

Pancreatic cancer

Axon guidance

Non-small cell lung cancer

Renal cell carcinoma

ErbB signaling pathway

Glioma

Thyroid cancer

p53 signaling pathway

Acute myeloid leukemia

Cell adhesion molecules (CAMs)

Fc gamma R-mediated phagocytosis

Leukocyte transendothelial migration

T cell receptor signaling pathway

TGF-beta signaling pathway

Tight junction

Calcium signaling pathway

Huntington's disease

Jak-STAT signaling pathway

Ubiquitin mediated proteolysis

Apoptosis

Basal cell carcinoma

Hematopoietic cell lineage

Melanogenesis

Natural killer cell mediated cytotoxicity

Progesterone-mediated oocyte maturation

Fc epsilon RI signaling pathway

Glycolysis / Gluconeogenesis

Long-term potentiation

Metabolism of xenobiotics by cytochrome P450

Oocyte meiosis

VEGF signaling pathway

Alzheimer's disease

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

B cell receptor signaling pathway

ECM-receptor interaction

Notch signaling pathway

Toll-like receptor signaling pathway

Dorso-ventral axis formation

Epithelial cell signaling in Helicobacter pylori infection

Fructose and mannose metabolism

Lysosome

NOD-like receptor signaling pathway

PPAR signaling pathway

Parkinson's disease

Prion diseases

Vascular smooth muscle contraction

mTOR signaling pathway

Adipocytokine signaling pathway

Amyotrophic lateral sclerosis (ALS)

Base excision repair

GnRH signaling pathway

Long-term depression

Pathogenic Escherichia coli infection

Purine metabolism

Type I diabetes mellitus

Viral myocarditis

Antigen processing and presentation

Butanoate metabolism

Complement and coagulation cascades

Drug metabolism - cytochrome P450

Gap junction

Glycosaminoglycan degradation

Hedgehog signaling pathway

Hypertrophic cardiomyopathy (HCM)

Inositol phosphate metabolism

Phosphatidylinositol signaling system

Vibrio cholerae infection

ABC transporters

Alanine

Arachidonic acid metabolism

C21-Steroid hormone metabolism

Cysteine and methionine metabolism

Cytosolic DNA-sensing pathway

Dilated cardiomyopathy

Drug metabolism - other enzymes

Galactose metabolism

Graft-versus-host disease

Histidine metabolism

Maturity onset diabetes of the young

Oxidative phosphorylation

Pentose phosphate pathway

Phenylalanine metabolism

Primary immunodeficiency

Pyruvate metabolism

Retinol metabolism

Sphingolipid metabolism

Starch and sucrose metabolism

Synthesis and degradation of ketone bodies

Systemic lupus erythematosus

Tryptophan metabolism

Type II diabetes mellitus

Tyrosine metabolism

Valine

aspartate and glutamate metabolism

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Androgen and estrogen metabolism

Arginine and proline metabolism

Autoimmune thyroid disease

Basal transcription factors

Cardiac muscle contraction

Citrate cycle (TCA cycle)

Fatty acid metabolism

Glycerolipid metabolism

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - lacto and neolacto series

Glyoxylate and dicarboxylate metabolism

Linoleic acid metabolism

Lysine degradation

One carbon pool by folate

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

Propanoate metabolism

RIG-I-like receptor signaling pathway

RNA degradation

Regulation of autophagy

Renin-angiotensin system

SNARE interactions in vesicular transport

Spliceosome

Taurine and hypotaurine metabolism

Terpenoid backbone biosynthesis

beta-Alanine metabolism

leucine and isoleucine biosynthesis

1

Yes