Over-expression Lysates

Proteins

Over-expression Lysates

Human

APH1A

DVL1

DISHEVELLED 2

DLL1

DLL3

HES1

HES5

JAGGED1

NOTCH1

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Transmembrane

Transcription Factors

ES Cell Differentiation/IPS

Stem cell relevant signaling - DSL/Notch pathway

Adult stem cells

Cancer stem cells

Stem cell - Pluripotency

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Pathways in cancer

Focal adhesion

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Colorectal cancer

Wnt signaling pathway

Hematopoietic cell lineage

Cell adhesion molecules (CAMs)

Neurotrophin signaling pathway

Regulation of actin cytoskeleton

Prostate cancer

ErbB signaling pathway

Melanoma

Pancreatic cancer

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Endometrial cancer

Basal cell carcinoma

Acute myeloid leukemia

Adherens junction

TGF-beta signaling pathway

Fc gamma R-mediated phagocytosis

Melanogenesis

Insulin signaling pathway

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Fc epsilon RI signaling pathway

Glioma

Small cell lung cancer

Chronic myeloid leukemia

Hedgehog signaling pathway

Adipocytokine signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

B cell receptor signaling pathway

Endocytosis

GnRH signaling pathway

Leukocyte transendothelial migration

Non-small cell lung cancer

Tight junction

Apoptosis

ECM-receptor interaction

Renal cell carcinoma

Chemokine signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Huntington's disease

Maturity onset diabetes of the young

VEGF signaling pathway

mTOR signaling pathway

Type II diabetes mellitus

Gap junction

Hypertrophic cardiomyopathy (HCM)

Dilated cardiomyopathy

Metabolic pathways

Systemic lupus erythematosus

Pathogenic Escherichia coli infection

Thyroid cancer

NOD-like receptor signaling pathway

Alzheimer's disease

Complement and coagulation cascades

Notch signaling pathway

Axon guidance

Bladder cancer

RIG-I-like receptor signaling pathway

Dorso-ventral axis formation

Calcium signaling pathway

Long-term depression

Oocyte meiosis

p53 signaling pathway

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

Autoimmune thyroid disease

Primary immunodeficiency

Prion diseases

Viral myocarditis

Allograft rejection

Cell cycle

Long-term potentiation

Type I diabetes mellitus

Vascular smooth muscle contraction

Glycolysis / Gluconeogenesis

Graft-versus-host disease

Starch and sucrose metabolism

PPAR signaling pathway

Citrate cycle (TCA cycle)

Lysosome

Neuroactive ligand-receptor interaction

Nicotinate and nicotinamide metabolism

Parkinson's disease

Phosphatidylinositol signaling system

Pyruvate metabolism

Renin-angiotensin system

Retinol metabolism

Tyrosine metabolism

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Asthma

Cardiac muscle contraction

Cysteine and methionine metabolism

Drug metabolism - cytochrome P450

Drug metabolism - other enzymes

Fructose and mannose metabolism

Galactose metabolism

Inositol phosphate metabolism

Linoleic acid metabolism

Metabolism of xenobiotics by cytochrome P450

Oxidative phosphorylation

Phenylalanine

Phenylalanine metabolism

Primary bile acid biosynthesis

Purine metabolism

Pyrimidine metabolism

Regulation of autophagy

Ubiquinone and other terpenoid-quinone biosynthesis

Ubiquitin mediated proteolysis

tyrosine and tryptophan biosynthesis

1

Yes