Over-expression Lysates

Proteins

Over-expression Lysates

Human

G PROTEIN ALPHA S

TAS1R1

ACCN1

EPITHELIAL SODIUM CHANNEL ALPHA

GNB3

PRKACA

PRKACB

ADCY8

EPITHELIAL SODIUM CHANNEL GAMMA

GNG13

GNG3

KV2.1

METABOTROPIC GLUTAMATE RECEPTOR 4

PDE1A

PHOSPHOLIPASE C BETA 2

PRKACG

PRKX

SCNN1B

TAS1R2

TAS2R1

TAS2R16

TAS2R3

TAS2R38

TAS2R5

TAS2R60

TRPM5

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Transmembrane

Ion Channels: Other

Protein Kinase

Secreted Protein

GPCR

Ion Channels: Potassium

Ion Channels: Transient receptor potential

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Insulin signaling pathway

Wnt signaling pathway

ErbB signaling pathway

Cell cycle

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Endocytosis

Hematopoietic cell lineage

Natural killer cell mediated cytotoxicity

Toll-like receptor signaling pathway

Prostate cancer

Apoptosis

GnRH signaling pathway

Axon guidance

Colorectal cancer

Purine metabolism

Alzheimer's disease

Oocyte meiosis

Pancreatic cancer

Melanogenesis

Tight junction

Adherens junction

Leukocyte transendothelial migration

Ubiquitin mediated proteolysis

Chronic myeloid leukemia

Small cell lung cancer

Vascular smooth muscle contraction

Gap junction

Glioma

Melanoma

VEGF signaling pathway

Fc epsilon RI signaling pathway

Renal cell carcinoma

TGF-beta signaling pathway

Acute myeloid leukemia

Lysosome

Cell adhesion molecules (CAMs)

Huntington's disease

B cell receptor signaling pathway

Dilated cardiomyopathy

Non-small cell lung cancer

Adipocytokine signaling pathway

Fc gamma R-mediated phagocytosis

Hypertrophic cardiomyopathy (HCM)

Endometrial cancer

Long-term potentiation

p53 signaling pathway

Complement and coagulation cascades

Long-term depression

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

NOD-like receptor signaling pathway

Phosphatidylinositol signaling system

Olfactory transduction

Amyotrophic lateral sclerosis (ALS)

ECM-receptor interaction

RIG-I-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Glycolysis / Gluconeogenesis

Bladder cancer

PPAR signaling pathway

Thyroid cancer

Pathogenic Escherichia coli infection

Type II diabetes mellitus

mTOR signaling pathway

Antigen processing and presentation

Inositol phosphate metabolism

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Basal cell carcinoma

Cardiac muscle contraction

Valine

Cytosolic DNA-sensing pathway

Glycerophospholipid metabolism

Hedgehog signaling pathway

Viral myocarditis

Arginine and proline metabolism

Base excision repair

Glycerolipid metabolism

Pyrimidine metabolism

leucine and isoleucine degradation

Primary immunodeficiency

Arachidonic acid metabolism

Parkinson's disease

Fatty acid metabolism

Drug metabolism - other enzymes

Vibrio cholerae infection

Lysine degradation

Nucleotide excision repair

Autoimmune thyroid disease

Prion diseases

Taste transduction

Tyrosine metabolism

Glutathione metabolism

Fructose and mannose metabolism

Pyruvate metabolism

Sphingolipid metabolism

Tryptophan metabolism

SNARE interactions in vesicular transport

Systemic lupus erythematosus

Butanoate metabolism

Notch signaling pathway

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Nitrogen metabolism

Galactose metabolism

Histidine metabolism

Proteasome

Type I diabetes mellitus

Linoleic acid metabolism

Pentose phosphate pathway

Propanoate metabolism

Regulation of autophagy

Alanine

Cysteine and methionine metabolism

aspartate and glutamate metabolism

Dorso-ventral axis formation

Homologous recombination

Androgen and estrogen metabolism

Maturity onset diabetes of the young

Oxidative phosphorylation

Renin-angiotensin system

Allograft rejection

Ether lipid metabolism

Ribosome

beta-Alanine metabolism

Citrate cycle (TCA cycle)

Porphyrin and chlorophyll metabolism

Mismatch repair

Riboflavin metabolism

Aminoacyl-tRNA biosynthesis

DNA replication

Glycosaminoglycan degradation

Pantothenate and CoA biosynthesis

Phenylalanine metabolism

Spliceosome

Graft-versus-host disease

Other glycan degradation

ABC transporters

Glycine

Selenoamino acid metabolism

serine and threonine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

leucine and isoleucine biosynthesis

N-Glycan biosynthesis

Primary bile acid biosynthesis

Asthma

Non-homologous end-joining

Folate biosynthesis

alpha-Linolenic acid metabolism

Ascorbate and aldarate metabolism

Basal transcription factors

Limonene and pinene degradation

Steroid biosynthesis

Terpenoid backbone biosynthesis

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

RNA degradation

Thiamine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Sulfur metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

RNA polymerase

Taurine and hypotaurine metabolism

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

O-Glycan biosynthesis

Phenylalanine

Protein export

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

1