Over-expression Lysates

Proteins

Over-expression Lysates

Human

STAT1

PIAS2

STAT3

STAT5A

C-MYC

CBL

E3 SUMO PROTEIN LIGASE PIAS4

EP300

INTERFERON REGULATORY FACTOR 9

PIAS1

PIAS3

STAT2

STAT4

STAT5B

STAT6

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Secreted Protein

Transmembrane

ES Cell Differentiation/IPS

Transcription Factors

Protein Kinase

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell - Pluripotency

Stem cell relevant signaling - DSL/Notch pathway

Phosphatase

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Pathways in cancer

Wnt signaling pathway

MAPK signaling pathway

Acute myeloid leukemia

Prostate cancer

Cell cycle

Metabolic pathways

Thyroid cancer

Huntington's disease

TGF-beta signaling pathway

Ubiquitin mediated proteolysis

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Pancreatic cancer

Purine metabolism

Pyrimidine metabolism

Basal transcription factors

Neurotrophin signaling pathway

Small cell lung cancer

Colorectal cancer

Cytosolic DNA-sensing pathway

T cell receptor signaling pathway

RNA polymerase

Adherens junction

Adipocytokine signaling pathway

Apoptosis

B cell receptor signaling pathway

Endometrial cancer

Melanogenesis

Chemokine signaling pathway

Basal cell carcinoma

Jak-STAT signaling pathway

Maturity onset diabetes of the young

ErbB signaling pathway

RIG-I-like receptor signaling pathway

Renal cell carcinoma

Antigen processing and presentation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Nucleotide excision repair

PPAR signaling pathway

Spliceosome

Insulin signaling pathway

Axon guidance

Endocytosis

Natural killer cell mediated cytotoxicity

Non-small cell lung cancer

Oocyte meiosis

RNA degradation

Tight junction

Amyotrophic lateral sclerosis (ALS)

Notch signaling pathway

VEGF signaling pathway

Bladder cancer

Melanoma

NOD-like receptor signaling pathway

p53 signaling pathway

Focal adhesion

Circadian rhythm - mammal

Neuroactive ligand-receptor interaction

Primary immunodeficiency

Epithelial cell signaling in Helicobacter pylori infection

Glioma

Pathogenic Escherichia coli infection

Alzheimer's disease

Base excision repair

DNA replication

Leukocyte transendothelial migration

Fc gamma R-mediated phagocytosis

Homologous recombination

Systemic lupus erythematosus

Calcium signaling pathway

Dorso-ventral axis formation

Long-term depression

Lysine degradation

Ribosome

Viral myocarditis

Long-term potentiation

Regulation of actin cytoskeleton

Cysteine and methionine metabolism

Cytokine-cytokine receptor interaction

Fc epsilon RI signaling pathway

GnRH signaling pathway

Type II diabetes mellitus

mTOR signaling pathway

Allograft rejection

Biosynthesis of unsaturated fatty acids

Graft-versus-host disease

Hedgehog signaling pathway

Type I diabetes mellitus

Valine

Aminoacyl-tRNA biosynthesis

Asthma

Autoimmune thyroid disease

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Ether lipid metabolism

Glycerolipid metabolism

Glycine

Glycolysis / Gluconeogenesis

Glyoxylate and dicarboxylate metabolism

Hematopoietic cell lineage

Hypertrophic cardiomyopathy (HCM)

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

Prion diseases

Progesterone-mediated oocyte maturation

Proteasome

Vascular smooth muscle contraction

leucine and isoleucine biosynthesis

leucine and isoleucine degradation

serine and threonine metabolism

1

Yes