Over-expression Lysates

Proteins

Over-expression Lysates

Human

HNF 4 ALPHA

GLUCOKINASE

HNF1 BETA

PAX6

BHLHA15

FOXA2

FOXA3

HES1

HEX

HNF4 GAMMA

HNF6

MAFA

MNX1

NEUROD1

NEUROGENIN3

NKX2.2

NKX6.1

NR5A2

AMYLIN

HNF1 ALPHA

INSULIN

PDX1

PYRUVATE KINASE

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Transcription Factors

ES Cell Differentiation/IPS

Nuclear Hormone Receptor

Embryonic stem cells

Adult stem cells

Cancer stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Neuroactive ligand-receptor interaction

Endocytosis

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Calcium signaling pathway

Purine metabolism

Huntington's disease

Alzheimer's disease

Ubiquitin mediated proteolysis

Insulin signaling pathway

Jak-STAT signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Tight junction

Cell cycle

Oocyte meiosis

Leukocyte transendothelial migration

Progesterone-mediated oocyte maturation

Cell adhesion molecules (CAMs)

Olfactory transduction

ErbB signaling pathway

T cell receptor signaling pathway

Lysosome

Spliceosome

Melanogenesis

Toll-like receptor signaling pathway

GnRH signaling pathway

Hematopoietic cell lineage

Systemic lupus erythematosus

Apoptosis

Prostate cancer

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

Adherens junction

Colorectal cancer

Parkinson's disease

Oxidative phosphorylation

Antigen processing and presentation

Pancreatic cancer

Pyrimidine metabolism

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

VEGF signaling pathway

Small cell lung cancer

TGF-beta signaling pathway

Melanoma

Fc epsilon RI signaling pathway

B cell receptor signaling pathway

Gap junction

Chronic myeloid leukemia

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Renal cell carcinoma

Acute myeloid leukemia

Glioma

Adipocytokine signaling pathway

PPAR signaling pathway

p53 signaling pathway

Long-term potentiation

Phosphatidylinositol signaling system

Ribosome

Complement and coagulation cascades

Pathogenic Escherichia coli infection

RIG-I-like receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Cardiac muscle contraction

NOD-like receptor signaling pathway

Endometrial cancer

Non-small cell lung cancer

Glycerophospholipid metabolism

Glycolysis / Gluconeogenesis

Long-term depression

Viral myocarditis

ECM-receptor interaction

Vibrio cholerae infection

Drug metabolism - cytochrome P450

mTOR signaling pathway

Amyotrophic lateral sclerosis (ALS)

Metabolism of xenobiotics by cytochrome P450

Cytosolic DNA-sensing pathway

Arginine and proline metabolism

Basal cell carcinoma

Inositol phosphate metabolism

Valine

Hedgehog signaling pathway

Thyroid cancer

RNA degradation

Glutathione metabolism

Drug metabolism - other enzymes

Bladder cancer

Retinol metabolism

Amino sugar and nucleotide sugar metabolism

Proteasome

Type II diabetes mellitus

leucine and isoleucine degradation

Autoimmune thyroid disease

Fatty acid metabolism

Glycerolipid metabolism

Arachidonic acid metabolism

Pyruvate metabolism

Starch and sucrose metabolism

Nucleotide excision repair

Notch signaling pathway

Base excision repair

Lysine degradation

SNARE interactions in vesicular transport

Taste transduction

Sphingolipid metabolism

Tryptophan metabolism

Type I diabetes mellitus

Tyrosine metabolism

Graft-versus-host disease

Alanine

aspartate and glutamate metabolism

Fructose and mannose metabolism

N-Glycan biosynthesis

Primary immunodeficiency

Cysteine and methionine metabolism

Butanoate metabolism

Prion diseases

Glycosphingolipid biosynthesis - lacto and neolacto series

DNA replication

Aminoacyl-tRNA biosynthesis

Ether lipid metabolism

Allograft rejection

Androgen and estrogen metabolism

Propanoate metabolism

Citrate cycle (TCA cycle)

Pentose phosphate pathway

Regulation of autophagy

Porphyrin and chlorophyll metabolism

Nitrogen metabolism

Glycine

O-Glycan biosynthesis

serine and threonine metabolism

Histidine metabolism

Selenoamino acid metabolism

Basal transcription factors

Dorso-ventral axis formation

Galactose metabolism

Homologous recombination

Nicotinate and nicotinamide metabolism

Asthma

RNA polymerase

Linoleic acid metabolism

Glycosaminoglycan degradation

Sulfur metabolism

beta-Alanine metabolism

Maturity onset diabetes of the young

Mismatch repair

Pantothenate and CoA biosynthesis

Primary bile acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Riboflavin metabolism

Pentose and glucuronate interconversions

Terpenoid backbone biosynthesis

Keratan sulfate biosynthesis

Other glycan degradation

One carbon pool by folate

Ascorbate and aldarate metabolism

Chondroitin sulfate biosynthesis

Renin-angiotensin system

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

ABC transporters

leucine and isoleucine biosynthesis

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

Non-homologous end-joining

Steroid biosynthesis

Limonene and pinene degradation

Taurine and hypotaurine metabolism

C21-Steroid hormone metabolism

Caffeine metabolism

Thiamine metabolism

Cyanoamino acid metabolism

Folate biosynthesis

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Methane metabolism

Lipoic acid metabolism

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

1

Yes