Over-expression Lysates

Proteins

Over-expression Lysates

Human

NME2

POLR1C

CMPK1

DTYMK

DUT

INOSINE TRIPHOSPHATE PYROPHOSPHATASE

P53R2

RRM2

UCK

UCKL1

AK3

DHODH

DIHYDROPYRIMIDINASE

DPYD

NM23A

NME4

NME5

NME6

NUCLEOSIDE DIPHOSPHATE KINASE 7

NUCLEOSIDE PHOSPHORYLASE

POLD1

POLR2C

PRIM1

RRM1

THYMIDINE KINASE 1

THYMIDINE KINASE 2

THYMIDINE PHOSPHORYLASE

THYMIDYLATE SYNTHASE

UCK2

UMPS

UPRT

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Transcription Factors

Transmembrane

Stem cell - Pluripotency

Secreted Protein

ES Cell Differentiation/IPS

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Cell cycle

T cell receptor signaling pathway

Endocytosis

Natural killer cell mediated cytotoxicity

Toll-like receptor signaling pathway

Axon guidance

GnRH signaling pathway

Colorectal cancer

Apoptosis

Prostate cancer

Hematopoietic cell lineage

Oocyte meiosis

Pancreatic cancer

Alzheimer's disease

Purine metabolism

Melanogenesis

Tight junction

Adherens junction

Ubiquitin mediated proteolysis

Leukocyte transendothelial migration

Chronic myeloid leukemia

VEGF signaling pathway

Fc epsilon RI signaling pathway

Gap junction

Vascular smooth muscle contraction

Glioma

Small cell lung cancer

TGF-beta signaling pathway

Acute myeloid leukemia

Renal cell carcinoma

Melanoma

B cell receptor signaling pathway

Huntington's disease

Fc gamma R-mediated phagocytosis

Adipocytokine signaling pathway

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Endometrial cancer

Lysosome

Non-small cell lung cancer

Long-term potentiation

Hypertrophic cardiomyopathy (HCM)

Phosphatidylinositol signaling system

NOD-like receptor signaling pathway

p53 signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Long-term depression

Olfactory transduction

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

Bladder cancer

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Amyotrophic lateral sclerosis (ALS)

Thyroid cancer

PPAR signaling pathway

Pathogenic Escherichia coli infection

mTOR signaling pathway

Type II diabetes mellitus

Inositol phosphate metabolism

Glycolysis / Gluconeogenesis

Antigen processing and presentation

Basal cell carcinoma

Cardiac muscle contraction

Glycerophospholipid metabolism

Hedgehog signaling pathway

Base excision repair

Cytosolic DNA-sensing pathway

Pyrimidine metabolism

Retinol metabolism

Drug metabolism - cytochrome P450

Glycerolipid metabolism

Viral myocarditis

Valine

Arginine and proline metabolism

Metabolism of xenobiotics by cytochrome P450

Parkinson's disease

Vibrio cholerae infection

Nucleotide excision repair

Taste transduction

Glutathione metabolism

Prion diseases

Fatty acid metabolism

Lysine degradation

Primary immunodeficiency

leucine and isoleucine degradation

Drug metabolism - other enzymes

SNARE interactions in vesicular transport

Sphingolipid metabolism

Arachidonic acid metabolism

Autoimmune thyroid disease

Fructose and mannose metabolism

Notch signaling pathway

Pyruvate metabolism

Proteasome

Tryptophan metabolism

Tyrosine metabolism

Nitrogen metabolism

Butanoate metabolism

Systemic lupus erythematosus

Amino sugar and nucleotide sugar metabolism

Dorso-ventral axis formation

Homologous recombination

Starch and sucrose metabolism

Alanine

Galactose metabolism

Regulation of autophagy

Type I diabetes mellitus

aspartate and glutamate metabolism

Cysteine and methionine metabolism

Histidine metabolism

Androgen and estrogen metabolism

Pentose phosphate pathway

Ether lipid metabolism

Linoleic acid metabolism

Oxidative phosphorylation

Propanoate metabolism

Renin-angiotensin system

Allograft rejection

Aminoacyl-tRNA biosynthesis

DNA replication

Mismatch repair

Riboflavin metabolism

Ribosome

Spliceosome

Pantothenate and CoA biosynthesis

Porphyrin and chlorophyll metabolism

ABC transporters

Citrate cycle (TCA cycle)

Glycosaminoglycan degradation

Maturity onset diabetes of the young

Other glycan degradation

beta-Alanine metabolism

Circadian rhythm - mammal

Graft-versus-host disease

Phenylalanine metabolism

Glycine

N-Glycan biosynthesis

Primary bile acid biosynthesis

Selenoamino acid metabolism

leucine and isoleucine biosynthesis

serine and threonine metabolism

C21-Steroid hormone metabolism

Non-homologous end-joining

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Asthma

Basal transcription factors

Steroid biosynthesis

Ascorbate and aldarate metabolism

Synthesis and degradation of ketone bodies

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Pentose and glucuronate interconversions

Thiamine metabolism

Folate biosynthesis

RNA degradation

Sulfur metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Glycosphingolipid biosynthesis - globo series

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

RNA polymerase

Fatty acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Methane metabolism

O-Glycan biosynthesis

Phenylalanine

Protein export

Taurine and hypotaurine metabolism

tyrosine and tryptophan biosynthesis

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - ganglio series

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Vitamin B6 metabolism

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