Over-expression Lysates

Proteins

Over-expression Lysates

Human

ACTIVIN A RECEPTOR TYPE IC

BMP4

DECORIN

ERK1

ERK2

PPP2R1B

SMAD5

ACTIVIN RECEPTOR TYPE IA

AMHR2

E2F5

FOLLISTATIN

ID1

LEFTY2

P15 INK4B

PP2A-BETA

SKP1

SMAD1

SMAD2

SMAD3

SMURF1

TGF BETA 2

ACTIVIN A RECEPTOR TYPE IB

ACTIVIN RECEPTOR TYPE IIA

ACVRL1

AMH

BMP5

BMP8B

BMPR1A

BMPR1B

BMPR2

C-MYC

COMP

CULLIN 1

DP1

E2F4

EP300

GDF 5

ID3

INHIBIN BETA A

INHIBIN BETA B

INHIBIN BETA C CHAIN

INHIBIN BETA E CHAIN

KAT3A / CBP

LEFTY

MADH7

MPS1

NODAL

NOGGIN

P107

P70 S6 KINASE BETA

PP2A-ALPHA

PPP2R1A

RB2 P130

RHOA

ROC1

ROCK2

S6K1

SMAD4

SMAD6

SMURF 2

TGF BETA 3

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

THBS3

THROMBOSPONDIN 1

THROMBOSPONDIN 2

TNF ALPHA

WB

HEK293T

C-Myc/DDK

WB

Druggable Genome

Transcription Factors

Secreted Protein

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Embryonic stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Adult stem cells

Induced pluripotent stem cells

Phosphatase

Stem cell - Pluripotency

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Cell cycle

T cell receptor signaling pathway

Endocytosis

Natural killer cell mediated cytotoxicity

Toll-like receptor signaling pathway

Axon guidance

GnRH signaling pathway

Colorectal cancer

Apoptosis

Prostate cancer

Oocyte meiosis

Pancreatic cancer

Purine metabolism

Alzheimer's disease

Hematopoietic cell lineage

Adherens junction

Melanogenesis

Tight junction

Ubiquitin mediated proteolysis

Chronic myeloid leukemia

Leukocyte transendothelial migration

Fc epsilon RI signaling pathway

VEGF signaling pathway

Gap junction

TGF-beta signaling pathway

Vascular smooth muscle contraction

Renal cell carcinoma

Small cell lung cancer

Glioma

Acute myeloid leukemia

B cell receptor signaling pathway

Melanoma

Huntington's disease

Fc gamma R-mediated phagocytosis

Endometrial cancer

Lysosome

Adipocytokine signaling pathway

Dilated cardiomyopathy

Non-small cell lung cancer

Long-term potentiation

Cell adhesion molecules (CAMs)

Hypertrophic cardiomyopathy (HCM)

Phosphatidylinositol signaling system

NOD-like receptor signaling pathway

p53 signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Long-term depression

Olfactory transduction

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Bladder cancer

Epithelial cell signaling in Helicobacter pylori infection

Amyotrophic lateral sclerosis (ALS)

Thyroid cancer

PPAR signaling pathway

Pathogenic Escherichia coli infection

mTOR signaling pathway

Inositol phosphate metabolism

Type II diabetes mellitus

Glycolysis / Gluconeogenesis

Antigen processing and presentation

Basal cell carcinoma

Cardiac muscle contraction

Glycerophospholipid metabolism

Hedgehog signaling pathway

Base excision repair

Cytosolic DNA-sensing pathway

Pyrimidine metabolism

Drug metabolism - cytochrome P450

Glycerolipid metabolism

Retinol metabolism

Valine

Viral myocarditis

Arginine and proline metabolism

Metabolism of xenobiotics by cytochrome P450

Parkinson's disease

Nucleotide excision repair

Vibrio cholerae infection

Glutathione metabolism

Taste transduction

Fatty acid metabolism

Lysine degradation

Prion diseases

leucine and isoleucine degradation

Drug metabolism - other enzymes

SNARE interactions in vesicular transport

Sphingolipid metabolism

Arachidonic acid metabolism

Fructose and mannose metabolism

Notch signaling pathway

Primary immunodeficiency

Autoimmune thyroid disease

Pyruvate metabolism

Proteasome

Tryptophan metabolism

Tyrosine metabolism

Nitrogen metabolism

Butanoate metabolism

Amino sugar and nucleotide sugar metabolism

Dorso-ventral axis formation

Starch and sucrose metabolism

Alanine

Galactose metabolism

Homologous recombination

Regulation of autophagy

Systemic lupus erythematosus

aspartate and glutamate metabolism

Cysteine and methionine metabolism

Histidine metabolism

Type I diabetes mellitus

Androgen and estrogen metabolism

Pentose phosphate pathway

Ether lipid metabolism

Linoleic acid metabolism

Oxidative phosphorylation

Propanoate metabolism

Renin-angiotensin system

Aminoacyl-tRNA biosynthesis

DNA replication

Mismatch repair

Riboflavin metabolism

Ribosome

Allograft rejection

Pantothenate and CoA biosynthesis

Porphyrin and chlorophyll metabolism

ABC transporters

Citrate cycle (TCA cycle)

Spliceosome

Glycosaminoglycan degradation

Maturity onset diabetes of the young

Other glycan degradation

beta-Alanine metabolism

Circadian rhythm - mammal

Phenylalanine metabolism

Glycine

N-Glycan biosynthesis

Primary bile acid biosynthesis

Selenoamino acid metabolism

leucine and isoleucine biosynthesis

serine and threonine metabolism

C21-Steroid hormone metabolism

Graft-versus-host disease

Non-homologous end-joining

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Asthma

Basal transcription factors

Steroid biosynthesis

Ascorbate and aldarate metabolism

Synthesis and degradation of ketone bodies

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Pentose and glucuronate interconversions

Thiamine metabolism

Folate biosynthesis

RNA degradation

Sulfur metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Glycosphingolipid biosynthesis - globo series

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

RNA polymerase

Fatty acid biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Methane metabolism

O-Glycan biosynthesis

Phenylalanine

Protein export

Taurine and hypotaurine metabolism

tyrosine and tryptophan biosynthesis

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - ganglio series

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Vitamin B6 metabolism

1

Yes