cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

PTEN

CTNNB1

KRAS

PRKCG

HRAS

NRAS

BETA CATENIN

PARD3

PPP2R2B

P21 RAS

CTNNA2

EPB41

EPB4IL2

G PROTEIN ALPHA INHIBITOR 2

MRAS

TJAP1

TJP2

AKT1

ALPHA 1 CATENIN

CDK4

CLAUDIN 14

EPB41L1

PPP2R1B

PPP2R2C

SHC

EPB41L3

MRCL3

MYL12B

MYOSIN

PKC THETA

PKC ZETA

RRAS2

SMOOTH MUSCLE MYOSIN HEAVY CHAIN 11

TJP1

ACTN2

AKT2

AKT3

ALPHA ACTININ

ALPHA FODRIN

CASK

CDC42

CKII ALPHA

CLAUDIN 10

CLAUDIN 15

CLAUDIN 2

CLAUDIN 5

CLAUDIN 7

CLDN19

CORTACTIN

CTNNA3

JUNCTIONAL ADHESION MOLECULE 2

L AFADIN

LLGL2

MAGI1

MUPP1

MYH10

MYH14

PARVIN GAMMA

PPP2R2D

ZONULA OCCLUDENS PROTEIN 3

ACTN3

AIP1

ANGIOMOTIN LIKE 1

CASEIN KINASE 2 BETA

CLAUDIN18

CRB3

DBPA

G PROTEIN ALPHA INHIBITOR 1

GAMMA ACTIN

HCLS1

JUNCTIONAL ADHESION MOLECULE 1

JUNCTIONAL ADHESION MOLECULE C

MAGI3

MPP5

MYL9

OLIGODENDROCYTE SPECIFIC PROTEIN

PAR6

PKC BETA 1

PKC DELTA

PP2A-BETA

PPP2R2A

RAB13

SEC8

SRC

VAPA

ZAK

ALPHA ACTININ 4

ASD3

BETA ACTIN

CINGULIN

CLAUDIN 1

CLAUDIN 17

CLAUDIN 20

CLAUDIN 22

CLAUDIN 23

CLAUDIN 3

CLAUDIN 4

CLAUDIN 6

CLAUDIN 8

CLAUDIN 9

Myc-DDK

Tag Free

pCMV6-Entry

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

Yes

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

Phosphatase

ES Cell Differentiation/IPS

Protein Kinase

Transcription Factors

Transmembrane

Stem cell relevant signaling - JAK/STAT signaling pathway

Metabolic pathways

Pathways in cancer

Insulin signaling pathway

Colorectal cancer

MAPK signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Ubiquitin mediated proteolysis

Endometrial cancer

Endocytosis

Pancreatic cancer

Prostate cancer

B cell receptor signaling pathway

Cytokine-cytokine receptor interaction

Chemokine signaling pathway

Fc epsilon RI signaling pathway

Melanoma

Mismatch repair

mTOR signaling pathway

Neuroactive ligand-receptor interaction

Calcium signaling pathway

Neurotrophin signaling pathway

ErbB signaling pathway

Natural killer cell mediated cytotoxicity

p53 signaling pathway

Glioma

Tight junction

Progesterone-mediated oocyte maturation

Type II diabetes mellitus

T cell receptor signaling pathway

Renal cell carcinoma

Thyroid cancer

Chronic myeloid leukemia

Non-small cell lung cancer

Wnt signaling pathway

Olfactory transduction

Melanogenesis

Leukocyte transendothelial migration

Jak-STAT signaling pathway

GnRH signaling pathway

Vascular smooth muscle contraction

Gap junction

Adherens junction

Axon guidance

VEGF signaling pathway

Glycolysis / Gluconeogenesis

Acute myeloid leukemia

Purine metabolism

Long-term depression

Primary immunodeficiency

Huntington's disease

Alzheimer's disease

Cell cycle

Bladder cancer

Long-term potentiation

Amino sugar and nucleotide sugar metabolism

Fc gamma R-mediated phagocytosis

Starch and sucrose metabolism

Small cell lung cancer

Homologous recombination

Apoptosis

Toll-like receptor signaling pathway

Dilated cardiomyopathy

Galactose metabolism

Maturity onset diabetes of the young

Oocyte meiosis

Phosphatidylinositol signaling system

Cell adhesion molecules (CAMs)

Dorso-ventral axis formation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Lysosome

Adipocytokine signaling pathway

Notch signaling pathway

Hypertrophic cardiomyopathy (HCM)

Inositol phosphate metabolism

Hematopoietic cell lineage

Spliceosome

Parkinson's disease

Pyrimidine metabolism

Oxidative phosphorylation

Systemic lupus erythematosus

Viral myocarditis

Epithelial cell signaling in Helicobacter pylori infection

TGF-beta signaling pathway

Vibrio cholerae infection

PPAR signaling pathway

Pathogenic Escherichia coli infection

ECM-receptor interaction

Basal cell carcinoma

Cardiac muscle contraction

Antigen processing and presentation

NOD-like receptor signaling pathway

Glycerophospholipid metabolism

RIG-I-like receptor signaling pathway

Taste transduction

Amyotrophic lateral sclerosis (ALS)

Complement and coagulation cascades

Ribosome

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Citrate cycle (TCA cycle)

Nucleotide excision repair

RNA degradation

Cytosolic DNA-sensing pathway

Arginine and proline metabolism

Glutathione metabolism

Drug metabolism - other enzymes

Retinol metabolism

Hedgehog signaling pathway

Arachidonic acid metabolism

Valine

Prion diseases

Tyrosine metabolism

Pyruvate metabolism

N-Glycan biosynthesis

Fatty acid metabolism

Base excision repair

Glycerolipid metabolism

Lysine degradation

leucine and isoleucine degradation

Autoimmune thyroid disease

Proteasome

ABC transporters

Sphingolipid metabolism

Cysteine and methionine metabolism

Type I diabetes mellitus

Tryptophan metabolism

Porphyrin and chlorophyll metabolism

DNA replication

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Graft-versus-host disease

Androgen and estrogen metabolism

Propanoate metabolism

Alanine

aspartate and glutamate metabolism

Basal transcription factors

Allograft rejection

Ether lipid metabolism

Histidine metabolism

Pentose phosphate pathway

RNA polymerase

Glycine

Selenoamino acid metabolism

serine and threonine metabolism

Butanoate metabolism

Nitrogen metabolism

Regulation of autophagy

Phenylalanine metabolism

Glycosaminoglycan degradation

Pentose and glucuronate interconversions

Linoleic acid metabolism

O-Glycan biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Asthma

Keratan sulfate biosynthesis

Pantothenate and CoA biosynthesis

beta-Alanine metabolism

Ascorbate and aldarate metabolism

One carbon pool by folate

Steroid biosynthesis

Biosynthesis of unsaturated fatty acids

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Other glycan degradation

Non-homologous end-joining

Sulfur metabolism

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

Circadian rhythm - mammal

Cyanoamino acid metabolism

Limonene and pinene degradation

Taurine and hypotaurine metabolism

Protein export

leucine and isoleucine biosynthesis

Folate biosynthesis

Thiamine metabolism

C21-Steroid hormone metabolism

Caffeine metabolism

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Fatty acid biosynthesis

Lysine biosynthesis

Methane metabolism

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Glutamine and D-glutamate metabolism

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

Neomycin

1

Yes

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