cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

GCK

TSC2

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

SORBS1

PRKACB

JNK1

PRKAR1B

KRAS

BRAF

EXOC7

CBL

JNK2

HEXOKINASE 1

P21 RAS

RAF1

PROTEIN KINASE A REGULATORY SUBUNIT I ALPHA

PIK3R5

NRAS

PKC ZETA

SHC

SOCS2

AKT1

GLUCOKINASE

PI 3 KINASE P85 ALPHA

PRKAG2

S6K1

JNK3

MNK1

PI 3 KINASE P55 GAMMA

SKIP

AKT3

HRAS

PDPK1

EIF4E

ERK1

GSK3 BETA

INSULIN

PHKA1

B RAF

PCK2

PPP1A

AMPK ALPHA 1

ELK1

HAMARTIN

IKK BETA

A RAF

AKT2

ERK2

GRB2

PHKG1

PHKG2

PROTEIN PHOSPHATASE 1 BETA

SREBP1

ACAT1

AMPK GAMMA 1

CBLB

EIF4EL3

FBP1

INSULIN RECEPTOR

MNK2

P38

PYRUVATE KINASE

BAD

CBL C

G6PC2

GLYCOGEN SYNTHASE 1

MAP2K2

PRKACA

PYGL

PYGM

CIP4

MEK1

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

RAPTOR

SHIP

SOCS4

GLUCOSE 6 PHOSPHATASE, CATALYTIC SUBUNIT

PDE3A

PHOSPHORYLASE B

PIK3CB

PP1C GAMMA

PTP1B

GRF2

PKC IOTA

AMPK ALPHA 2

ESA1

HEXOKINASE TYPE III

MEK2

P70 S6 KINASE BETA

PPP1R3B

PRKACG

PRKX

TUBERIN

AMPK BETA 1

AMPK BETA 2

AMPK GAMMA 3

CALM1

CALM3

CALML3

CALMODULIN

Plasmids

Myc-DDK

Tag Free

mGFP

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

pCMV6-XL5-DDK-His

No

Yes

TrueORF

LentiORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Phosphatase

Transmembrane

Stem cell - Pluripotency

Secreted Protein

Stem cell relevant signaling - JAK/STAT signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Calcium signaling pathway

Insulin signaling pathway

Neurotrophin signaling pathway

Ubiquitin mediated proteolysis

Wnt signaling pathway

Olfactory transduction

Colorectal cancer

Huntington's disease

Purine metabolism

Natural killer cell mediated cytotoxicity

Alzheimer's disease

Jak-STAT signaling pathway

Prostate cancer

Progesterone-mediated oocyte maturation

Tight junction

Axon guidance

Cell cycle

Pancreatic cancer

Leukocyte transendothelial migration

T cell receptor signaling pathway

ErbB signaling pathway

Melanoma

Cell adhesion molecules (CAMs)

Oocyte meiosis

Endometrial cancer

Apoptosis

Vascular smooth muscle contraction

B cell receptor signaling pathway

GnRH signaling pathway

Melanogenesis

p53 signaling pathway

Adherens junction

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Lysosome

Fc epsilon RI signaling pathway

Fc gamma R-mediated phagocytosis

Glioma

Small cell lung cancer

Dilated cardiomyopathy

Gap junction

VEGF signaling pathway

Renal cell carcinoma

Non-small cell lung cancer

Hematopoietic cell lineage

mTOR signaling pathway

Hypertrophic cardiomyopathy (HCM)

Spliceosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Parkinson's disease

Long-term potentiation

Acute myeloid leukemia

Long-term depression

Oxidative phosphorylation

Type II diabetes mellitus

Systemic lupus erythematosus

Pyrimidine metabolism

Bladder cancer

Thyroid cancer

Adipocytokine signaling pathway

Glycolysis / Gluconeogenesis

TGF-beta signaling pathway

Viral myocarditis

PPAR signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Cardiac muscle contraction

Complement and coagulation cascades

Mismatch repair

Ribosome

Glycerophospholipid metabolism

Amino sugar and nucleotide sugar metabolism

Starch and sucrose metabolism

Primary immunodeficiency

Pathogenic Escherichia coli infection

Vibrio cholerae infection

Drug metabolism - cytochrome P450

Metabolism of xenobiotics by cytochrome P450

Inositol phosphate metabolism

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Arginine and proline metabolism

Notch signaling pathway

RNA degradation

Retinol metabolism

Homologous recombination

Drug metabolism - other enzymes

Glutathione metabolism

Valine

Arachidonic acid metabolism

Galactose metabolism

Maturity onset diabetes of the young

Taste transduction

Nucleotide excision repair

Tyrosine metabolism

N-Glycan biosynthesis

Dorso-ventral axis formation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Fatty acid metabolism

leucine and isoleucine degradation

Glycerolipid metabolism

Sphingolipid metabolism

Proteasome

ABC transporters

Prion diseases

Type I diabetes mellitus

Citrate cycle (TCA cycle)

Base excision repair

Cysteine and methionine metabolism

Tryptophan metabolism

Graft-versus-host disease

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Alanine

aspartate and glutamate metabolism

Allograft rejection

Ether lipid metabolism

Propanoate metabolism

DNA replication

Aminoacyl-tRNA biosynthesis

Glycosphingolipid biosynthesis - lacto and neolacto series

Glycine

serine and threonine metabolism

Regulation of autophagy

Butanoate metabolism

Histidine metabolism

Pentose phosphate pathway

Basal transcription factors

Nitrogen metabolism

Selenoamino acid metabolism

Glycosaminoglycan degradation

RNA polymerase

Phenylalanine metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Asthma

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

One carbon pool by folate

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Primary bile acid biosynthesis

Riboflavin metabolism

Other glycan degradation

Renin-angiotensin system

Chondroitin sulfate biosynthesis

alpha-Linolenic acid metabolism

Non-homologous end-joining

Sulfur metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Cyanoamino acid metabolism

Taurine and hypotaurine metabolism

leucine and isoleucine biosynthesis

Protein export

Folate biosynthesis

C21-Steroid hormone metabolism

Thiamine metabolism

Caffeine metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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