活动过滤器
优化搜索结果
Species
Target Symbol
- BRCA1 (397)
- BTK (299)
- BRCA2 (280)
- GCK (261)
- TSC2 (256)
- MEN1 (248)
- MLH1 (247)
- MSH2 (219)
- RET (187)
- NOTCH3 (161)
- NF2 (114)
- MSH6 (92)
- STK11 (86)
- CREM (85)
- FGFR1 (74)
- GNAS (72)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (68)
- VEGFA (67)
- WT1 (66)
- FH (63)
- E4 (61)
- KCNMA1 (61)
- L2 (60)
- BDNF (58)
- TPM1 (58)
- NRG1 (53)
- CACNA1G (52)
- L1 (50)
- UTY (49)
- EGFR (47)
- PTEN (47)
- CACNA1C (45)
- CTNND1 (45)
- ERCC2 (43)
- PCDH15 (43)
- TNNT3 (41)
- CTNNB1 (40)
- ST3GAL3 (40)
- E3 (39)
- FLT4 (39)
- PLAGL1 (39)
- IKAROS (37)
- TCF7L2 (37)
- ANKS1B (36)
- ARPP21 (36)
- BRAF (36)
- KCNJ15 (36)
- NFATC2 (36)
- SYTL2 (36)
- DISC1 (35)
- DYNC1I2 (35)
- E1 (35)
- NDRG2 (35)
- PDE9A (35)
- UBE2V1 (35)
- TERT (34)
- EMA (33)
- IKZF3 (33)
- KCNQ2 (33)
- LDB3 (33)
- MU OPIOID RECEPTOR (33)
- E6 (32)
- E7 (32)
- FGFR2 (32)
- PRKACB (32)
- RUNX1T1 (32)
- ABLIM2 (31)
- ATF2 (31)
- BORIS (31)
- E2 (31)
- ZNF133 (31)
- AIRE (30)
- CEACAM1 (30)
- IFI27 (30)
- MIER1 (30)
- MYADM (30)
- TNIP1 (30)
- ESTROGEN RELATED RECEPTOR GAMMA (29)
- FHL1 (29)
- LAIR1 (29)
- MBD1 (29)
- MBNL1 (29)
- NDRG4 (29)
- PGAP2 (29)
- TPD52L2 (29)
- TRPM3 (29)
- ZNF302 (29)
- ATP2C1 (28)
- DNMT3B (28)
- EEF1D (28)
- GTF2IRD1 (28)
- HMGA1 (28)
- HRAS (28)
- ODF2 (28)
- PKIB (28)
- SH2B1 (28)
- SMOX (28)
- TMEM176B (28)
- ZMYND8 (28)
- CBL (27)
Mutants
Families
- Druggable Genome (25228)
- Transmembrane (14534)
- Transcription Factors (7167)
- Secreted Protein (3396)
- Protein Kinase (2604)
- Stem cell - Pluripotency (1287)
- Protease (1229)
- ES Cell Differentiation/IPS (1120)
- GPCR (785)
- Phosphatase (591)
- Ion Channels: Other (410)
- Nuclear Hormone Receptor (304)
- Adult stem cells (264)
- Ion Channels: Potassium (217)
- Embryonic stem cells (199)
- Cancer stem cells (146)
- Ion Channels: Cys-loop Receptors (133)
- P450 (109)
- Induced pluripotent stem cells (105)
- Stem cell relevant signaling - JAK/STAT signaling pathway (98)
- Ion Channels: Calcium (92)
- Ion Channels: Transient receptor potential (83)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (63)
- Ion Channels: Glutamate Receptors (60)
- Stem cell relevant signaling - Wnt Signaling pathway (49)
- Stem cell relevant signaling - DSL/Notch pathway (45)
- Ion Channels: ATP Receptors (35)
- Ion Channels: Sodium (30)
- Ion Channels: Cyclic nucleotide gated (20)
Pathways
- Metabolic pathways (3466)
- Pathways in cancer (2733)
- MAPK signaling pathway (1279)
- Insulin signaling pathway (1153)
- Colorectal cancer (1081)
- Regulation of actin cytoskeleton (1003)
- Focal adhesion (983)
- Ubiquitin mediated proteolysis (932)
- Endocytosis (884)
- Endometrial cancer (826)
- Cytokine-cytokine receptor interaction (819)
- Olfactory transduction (818)
- Neuroactive ligand-receptor interaction (785)
- Pancreatic cancer (783)
- Chemokine signaling pathway (782)
- Prostate cancer (755)
- Calcium signaling pathway (726)
- B cell receptor signaling pathway (720)
- Neurotrophin signaling pathway (679)
- Fc epsilon RI signaling pathway (676)
- Melanoma (654)
- Progesterone-mediated oocyte maturation (647)
- mTOR signaling pathway (642)
- Natural killer cell mediated cytotoxicity (640)
- ErbB signaling pathway (634)
- Tight junction (630)
- Mismatch repair (616)
- p53 signaling pathway (612)
- Wnt signaling pathway (582)
- T cell receptor signaling pathway (574)
- Glioma (570)
- Leukocyte transendothelial migration (558)
- Jak-STAT signaling pathway (557)
- Purine metabolism (553)
- Type II diabetes mellitus (538)
- Axon guidance (537)
- Chronic myeloid leukemia (534)
- Renal cell carcinoma (530)
- Vascular smooth muscle contraction (525)
- Melanogenesis (524)
- Thyroid cancer (515)
- Huntington's disease (514)
- GnRH signaling pathway (512)
- Non-small cell lung cancer (512)
- Gap junction (509)
- Adherens junction (497)
- Alzheimer's disease (495)
- Cell cycle (482)
- VEGF signaling pathway (472)
- Long-term depression (468)
- Acute myeloid leukemia (456)
- Glycolysis / Gluconeogenesis (445)
- Oocyte meiosis (441)
- Apoptosis (434)
- Fc gamma R-mediated phagocytosis (432)
- Small cell lung cancer (431)
- Long-term potentiation (421)
- Primary immunodeficiency (417)
- Bladder cancer (404)
- Dilated cardiomyopathy (404)
- Toll-like receptor signaling pathway (402)
- Amino sugar and nucleotide sugar metabolism (398)
- Starch and sucrose metabolism (385)
- Cell adhesion molecules (CAMs) (382)
- Homologous recombination (371)
- Lysosome (364)
- Phosphatidylinositol signaling system (361)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (357)
- Adipocytokine signaling pathway (323)
- Galactose metabolism (322)
- Maturity onset diabetes of the young (317)
- Hypertrophic cardiomyopathy (HCM) (315)
- Pyrimidine metabolism (314)
- Dorso-ventral axis formation (302)
- Hematopoietic cell lineage (296)
- Parkinson's disease (288)
- Systemic lupus erythematosus (286)
- Spliceosome (283)
- Notch signaling pathway (281)
- Inositol phosphate metabolism (280)
- Oxidative phosphorylation (276)
- PPAR signaling pathway (257)
- Viral myocarditis (252)
- ECM-receptor interaction (232)
- Vibrio cholerae infection (230)
- Epithelial cell signaling in Helicobacter pylori infection (229)
- TGF-beta signaling pathway (229)
- Glycerophospholipid metabolism (224)
- Cardiac muscle contraction (223)
- Pathogenic Escherichia coli infection (222)
- Antigen processing and presentation (219)
- NOD-like receptor signaling pathway (216)
- Basal cell carcinoma (211)
- Amyotrophic lateral sclerosis (ALS) (207)
- RIG-I-like receptor signaling pathway (207)
- Taste transduction (206)
- Drug metabolism - cytochrome P450 (205)
- Metabolism of xenobiotics by cytochrome P450 (201)
- Complement and coagulation cascades (187)
- RNA degradation (187)
- Ribosome (183)
- Arginine and proline metabolism (174)
- Glutathione metabolism (173)
- Nucleotide excision repair (173)
- Cytosolic DNA-sensing pathway (171)
- Citrate cycle (TCA cycle) (168)
- Drug metabolism - other enzymes (164)
- Arachidonic acid metabolism (161)
- Retinol metabolism (158)
- Valine (150)
- Hedgehog signaling pathway (142)
- Tyrosine metabolism (141)
- Fatty acid metabolism (134)
- N-Glycan biosynthesis (134)
- Prion diseases (133)
- Base excision repair (131)
- Pyruvate metabolism (131)
- Lysine degradation (128)
- leucine and isoleucine degradation (128)
- ABC transporters (125)
- Glycerolipid metabolism (122)
- Proteasome (119)
- Autoimmune thyroid disease (117)
- Sphingolipid metabolism (112)
- Cysteine and methionine metabolism (108)
- Tryptophan metabolism (107)
- Porphyrin and chlorophyll metabolism (105)
- Type I diabetes mellitus (105)
- Glycosphingolipid biosynthesis - lacto and neolacto series (104)
- DNA replication (103)
- Aminoacyl-tRNA biosynthesis (97)
- Fructose and mannose metabolism (94)
- Propanoate metabolism (94)
- Histidine metabolism (93)
- Androgen and estrogen metabolism (90)
- SNARE interactions in vesicular transport (90)
- Alanine (86)
- aspartate and glutamate metabolism (86)
- Graft-versus-host disease (85)
- Pentose phosphate pathway (85)
- Selenoamino acid metabolism (85)
- Basal transcription factors (84)
- RNA polymerase (84)
- Nitrogen metabolism (82)
- Regulation of autophagy (82)
- Ether lipid metabolism (81)
- Butanoate metabolism (80)
- Allograft rejection (79)
- Phenylalanine metabolism (78)
- Glycine (74)
- serine and threonine metabolism (74)
- Pentose and glucuronate interconversions (72)
- Glycosaminoglycan degradation (70)
- Linoleic acid metabolism (69)
- Pantothenate and CoA biosynthesis (69)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (63)
- Keratan sulfate biosynthesis (63)
- One carbon pool by folate (62)
- Steroid biosynthesis (62)
- O-Glycan biosynthesis (58)
- Ascorbate and aldarate metabolism (57)
- Asthma (55)
- Biosynthesis of unsaturated fatty acids (55)
- Nicotinate and nicotinamide metabolism (55)
- beta-Alanine metabolism (54)
- Heparan sulfate biosynthesis (53)
- Chondroitin sulfate biosynthesis (50)
- Riboflavin metabolism (50)
- Primary bile acid biosynthesis (49)
- Glycosphingolipid biosynthesis - ganglio series (46)
- Non-homologous end-joining (46)
- alpha-Linolenic acid metabolism (46)
- Sulfur metabolism (45)
- Terpenoid backbone biosynthesis (45)
- Other glycan degradation (44)
- Taurine and hypotaurine metabolism (43)
- Cyanoamino acid metabolism (41)
- Glycosphingolipid biosynthesis - globo series (40)
- Glyoxylate and dicarboxylate metabolism (40)
- Circadian rhythm - mammal (39)
- Protein export (39)
- Limonene and pinene degradation (38)
- leucine and isoleucine biosynthesis (36)
- Renin-angiotensin system (34)
- Thiamine metabolism (29)
- Folate biosynthesis (25)
- C21-Steroid hormone metabolism (24)
- Lysine biosynthesis (22)
- Caffeine metabolism (21)
- Synthesis and degradation of ketone bodies (21)
- Fatty acid elongation in mitochondria (20)
- Lipoic acid metabolism (18)
- Fatty acid biosynthesis (16)
- Biotin metabolism (14)
- Methane metabolism (14)
- O-Mannosyl glycan biosynthesis (14)
- Phenylalanine (13)
- Ubiquinone and other terpenoid-quinone biosynthesis (13)
- tyrosine and tryptophan biosynthesis (13)
- D-Glutamine and D-glutamate metabolism (11)
- Vitamin B6 metabolism (6)
- D-Arginine and D-ornithine metabolism (1)