cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

APH1A

LUNATIC FRINGE

PTCRA

PRESENILIN 2

NICASTRIN

PEN2

PRESENILIN 1

DLL3

JAGGED 2

DLL1

DLL4

JAGGED1

NOTCH2

RFNG

ADAM17

JAG2

LFNG

NCSTN

PSEN1

Plasmids

Myc-DDK

Tag Free

TurboGFP

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL4

pCMV6-XL5

pCMV6-AC

PCMV6-Neo

pCMV6-XL6

No

Yes

LentiORF

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transmembrane

Transcription Factors

ES Cell Differentiation/IPS

Stem cell relevant signaling - DSL/Notch pathway

Stem cell - Pluripotency

Cancer stem cells

Protease

Adult stem cells

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Cell adhesion molecules (CAMs)

Calcium signaling pathway

Pathways in cancer

MAPK signaling pathway

Hematopoietic cell lineage

Endocytosis

Regulation of actin cytoskeleton

Alzheimer's disease

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Dilated cardiomyopathy

Axon guidance

Hypertrophic cardiomyopathy (HCM)

Focal adhesion

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Lysosome

Vascular smooth muscle contraction

Antigen processing and presentation

ECM-receptor interaction

Chemokine signaling pathway

Adherens junction

Huntington's disease

ABC transporters

N-Glycan biosynthesis

Leukocyte transendothelial migration

Viral myocarditis

Oxidative phosphorylation

Cardiac muscle contraction

Parkinson's disease

Prostate cancer

Colorectal cancer

Drug metabolism - cytochrome P450

Melanogenesis

Systemic lupus erythematosus

Retinol metabolism

Melanoma

ErbB signaling pathway

GnRH signaling pathway

Graft-versus-host disease

SNARE interactions in vesicular transport

Adipocytokine signaling pathway

Gap junction

Autoimmune thyroid disease

Glycosphingolipid biosynthesis - lacto and neolacto series

PPAR signaling pathway

Purine metabolism

Metabolism of xenobiotics by cytochrome P450

Neurotrophin signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Tight junction

Apoptosis

Glycerophospholipid metabolism

Allograft rejection

Type I diabetes mellitus

Type II diabetes mellitus

Wnt signaling pathway

Sphingolipid metabolism

Taste transduction

Long-term potentiation

Toll-like receptor signaling pathway

O-Glycan biosynthesis

Amyotrophic lateral sclerosis (ALS)

Drug metabolism - other enzymes

Basal cell carcinoma

Starch and sucrose metabolism

Thyroid cancer

Pancreatic cancer

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

TGF-beta signaling pathway

Androgen and estrogen metabolism

Long-term depression

Vibrio cholerae infection

Porphyrin and chlorophyll metabolism

Arachidonic acid metabolism

Keratan sulfate biosynthesis

Primary immunodeficiency

T cell receptor signaling pathway

Heparan sulfate biosynthesis

Asthma

Fatty acid metabolism

Complement and coagulation cascades

Ether lipid metabolism

Fc gamma R-mediated phagocytosis

Notch signaling pathway

Hedgehog signaling pathway

p53 signaling pathway

Bladder cancer

Pentose and glucuronate interconversions

Chondroitin sulfate biosynthesis

Ascorbate and aldarate metabolism

B cell receptor signaling pathway

Glycerolipid metabolism

Glycosphingolipid biosynthesis - globo series

Pyrimidine metabolism

Linoleic acid metabolism

Glycosphingolipid biosynthesis - ganglio series

Prion diseases

Glutathione metabolism

Endometrial cancer

Tyrosine metabolism

Glioma

Non-small cell lung cancer

Renin-angiotensin system

Fc epsilon RI signaling pathway

Small cell lung cancer

Steroid biosynthesis

Progesterone-mediated oocyte maturation

Chronic myeloid leukemia

Biosynthesis of unsaturated fatty acids

Cytosolic DNA-sensing pathway

Oocyte meiosis

Renal cell carcinoma

Insulin signaling pathway

Riboflavin metabolism

Pathogenic Escherichia coli infection

Dorso-ventral axis formation

Glycosaminoglycan degradation

Nicotinate and nicotinamide metabolism

Galactose metabolism

Ubiquitin mediated proteolysis

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

RIG-I-like receptor signaling pathway

VEGF signaling pathway

Phosphatidylinositol signaling system

Cyanoamino acid metabolism

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Inositol phosphate metabolism

Amino sugar and nucleotide sugar metabolism

Phenylalanine metabolism

Tryptophan metabolism

C21-Steroid hormone metabolism

NOD-like receptor signaling pathway

Nitrogen metabolism

beta-Alanine metabolism

Caffeine metabolism

Glycolysis / Gluconeogenesis

Glycine

Protein export

serine and threonine metabolism

Acute myeloid leukemia

O-Mannosyl glycan biosynthesis

Propanoate metabolism

Sulfur metabolism

Valine

leucine and isoleucine degradation

Limonene and pinene degradation

Citrate cycle (TCA cycle)

Cell cycle

Arginine and proline metabolism

Histidine metabolism

Lysine degradation

Other glycan degradation

Pantothenate and CoA biosynthesis

Pyruvate metabolism

Base excision repair

Fatty acid elongation in mitochondria

Butanoate metabolism

Terpenoid backbone biosynthesis

Maturity onset diabetes of the young

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Neomycin

None

Puromycin

1

Yes

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