cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

EGFR

KRAS

AKT1

P53

MLH1

BETA CATENIN

MET

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

AKT3

APC

B RAF

C-MYC

CASPASE 3

ERK2

FRIZZLED 4

LEF1

MEK1

MSH2

MSH6

TGF BETA 2

A RAF

AKT2

APPL

AXIN 2

BAX

BCL2

BIRC5

C FOS

C-JUN

CASPASE 9

CTNNB1

CYCLIN D1

DVL1

ERK1

FRIZZLED 7

FZD3

GRB2

GSK3 BETA

IGF1 RECEPTOR

MSH3

PDGF RECEPTOR BETA

PI 3 KINASE P85 ALPHA

PI 3 KINASE P85 BETA

PIK3CB

RAF1

SMAD2

SMAD3

SMAD4

TCF7L1

TCF7L2

TGF BETA 1

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

Plasmids

Myc-DDK

Tag Free

TurboGFP

mGFP

DDK-His

pCMV6-Entry

pLenti-C-Myc-DDK

pCMV6-AC-Myc-DDK

No

Yes

TrueORF Gold, TrueORF

TrueORF

LentiORF

Druggable Genome

ES Cell Differentiation/IPS

Protein Kinase

Transmembrane

Transcription Factors

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Secreted Protein

Adult stem cells

Cancer stem cells

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

GPCR

Induced pluripotent stem cells

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Cytokine-cytokine receptor interaction

Chemokine signaling pathway

Prostate cancer

Neuroactive ligand-receptor interaction

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Colorectal cancer

T cell receptor signaling pathway

Insulin signaling pathway

ErbB signaling pathway

Endocytosis

Melanoma

Chronic myeloid leukemia

Endometrial cancer

Calcium signaling pathway

Alzheimer's disease

Axon guidance

Cell cycle

Pancreatic cancer

Huntington's disease

Renal cell carcinoma

Natural killer cell mediated cytotoxicity

Glioma

Toll-like receptor signaling pathway

Tight junction

Non-small cell lung cancer

Leukocyte transendothelial migration

Small cell lung cancer

Acute myeloid leukemia

Melanogenesis

Apoptosis

GnRH signaling pathway

Adherens junction

VEGF signaling pathway

B cell receptor signaling pathway

Progesterone-mediated oocyte maturation

Fc epsilon RI signaling pathway

Bladder cancer

Ubiquitin mediated proteolysis

Cell adhesion molecules (CAMs)

Fc gamma R-mediated phagocytosis

TGF-beta signaling pathway

Gap junction

Hematopoietic cell lineage

Adipocytokine signaling pathway

p53 signaling pathway

Long-term potentiation

Lysosome

RIG-I-like receptor signaling pathway

Thyroid cancer

Vascular smooth muscle contraction

Oocyte meiosis

Long-term depression

Purine metabolism

Parkinson's disease

mTOR signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Basal cell carcinoma

Amyotrophic lateral sclerosis (ALS)

Pathogenic Escherichia coli infection

Dilated cardiomyopathy

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

NOD-like receptor signaling pathway

PPAR signaling pathway

Type II diabetes mellitus

ECM-receptor interaction

Spliceosome

Hypertrophic cardiomyopathy (HCM)

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Oxidative phosphorylation

Systemic lupus erythematosus

Dorso-ventral axis formation

Glycolysis / Gluconeogenesis

Metabolism of xenobiotics by cytochrome P450

Notch signaling pathway

Citrate cycle (TCA cycle)

Glutathione metabolism

Antigen processing and presentation

Cardiac muscle contraction

Maturity onset diabetes of the young

Prion diseases

Viral myocarditis

Drug metabolism - cytochrome P450

Vibrio cholerae infection

Phosphatidylinositol signaling system

Proteasome

Sphingolipid metabolism

Arginine and proline metabolism

Glycerophospholipid metabolism

Inositol phosphate metabolism

Pyruvate metabolism

Retinol metabolism

Type I diabetes mellitus

Allograft rejection

Arachidonic acid metabolism

Lysine degradation

Primary immunodeficiency

Autoimmune thyroid disease

Complement and coagulation cascades

Cysteine and methionine metabolism

Fatty acid metabolism

Mismatch repair

Pyrimidine metabolism

Tryptophan metabolism

Nucleotide excision repair

Olfactory transduction

Regulation of autophagy

ABC transporters

DNA replication

Drug metabolism - other enzymes

Fructose and mannose metabolism

Starch and sucrose metabolism

Tyrosine metabolism

Valine

Androgen and estrogen metabolism

Graft-versus-host disease

N-Glycan biosynthesis

Alanine

Asthma

Base excision repair

Glycine

Nicotinate and nicotinamide metabolism

Nitrogen metabolism

RNA degradation

Ribosome

Taste transduction

aspartate and glutamate metabolism

serine and threonine metabolism

Butanoate metabolism

Galactose metabolism

Homologous recombination

SNARE interactions in vesicular transport

leucine and isoleucine degradation

Aminoacyl-tRNA biosynthesis

Glycerolipid metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Linoleic acid metabolism

Propanoate metabolism

Glycosaminoglycan degradation

Phenylalanine metabolism

Renin-angiotensin system

Selenoamino acid metabolism

Amino sugar and nucleotide sugar metabolism

Biosynthesis of unsaturated fatty acids

C21-Steroid hormone metabolism

Ether lipid metabolism

Histidine metabolism

Non-homologous end-joining

O-Glycan biosynthesis

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

Steroid biosynthesis

Chondroitin sulfate biosynthesis

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

One carbon pool by folate

Other glycan degradation

Sulfur metabolism

beta-Alanine metabolism

Ascorbate and aldarate metabolism

Circadian rhythm - mammal

Methane metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

RNA polymerase

Synthesis and degradation of ketone bodies

leucine and isoleucine biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Folate biosynthesis

Riboflavin metabolism

Terpenoid backbone biosynthesis

Basal transcription factors

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Phenylalanine

Taurine and hypotaurine metabolism

Thiamine metabolism

tyrosine and tryptophan biosynthesis

Biotin metabolism

Fatty acid biosynthesis

O-Mannosyl glycan biosynthesis

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

Neomycin

None

1

Yes

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