cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

KRAS

AKT1

AKT3

B RAF

CDK4

ERK2

EVI1

NRAS

P21

P21 RAS

P53

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

RUNX1

TGF BETA 2

A RAF

AKT2

BCL X

C ABL

C-MYC

CBL

CBLB

CDKN1B

CRKL

CYCLIN D1

E2F1

ERK1

GRB2

HDAC1

HDAC2

HRAS

IKB ALPHA

IKK BETA

MDM2

MEK1

MEK2

NF-KB P65

NFKB1

P16INK4A

P27 KIP 1

P38

PI 3 KINASE P85 ALPHA

PI 3 KINASE P85 BETA

PIK3CB

RAF1

SHP2

SMAD3

SMAD4

STAT5A

STAT5B

TGF BETA 1

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

Myc-DDK

Tag Free

pCMV6-Entry

pLenti-C-Myc-DDK

pCMV6-AC-Myc-DDK

No

Yes

TrueORF Gold, TrueORF

TrueORF

Druggable Genome

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Transmembrane

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Cancer stem cells

Induced pluripotent stem cells

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Cytokine-cytokine receptor interaction

Chemokine signaling pathway

Neuroactive ligand-receptor interaction

Neurotrophin signaling pathway

T cell receptor signaling pathway

Jak-STAT signaling pathway

Prostate cancer

Insulin signaling pathway

Wnt signaling pathway

Colorectal cancer

Endocytosis

ErbB signaling pathway

Axon guidance

Calcium signaling pathway

Alzheimer's disease

Melanoma

Chronic myeloid leukemia

Endometrial cancer

Renal cell carcinoma

Tight junction

Huntington's disease

Pancreatic cancer

Natural killer cell mediated cytotoxicity

Toll-like receptor signaling pathway

Cell cycle

Glioma

Leukocyte transendothelial migration

GnRH signaling pathway

Melanogenesis

VEGF signaling pathway

Apoptosis

Acute myeloid leukemia

B cell receptor signaling pathway

Non-small cell lung cancer

Progesterone-mediated oocyte maturation

Small cell lung cancer

Ubiquitin mediated proteolysis

Adherens junction

Fc epsilon RI signaling pathway

Cell adhesion molecules (CAMs)

Fc gamma R-mediated phagocytosis

Gap junction

TGF-beta signaling pathway

Bladder cancer

Hematopoietic cell lineage

Adipocytokine signaling pathway

Lysosome

Vascular smooth muscle contraction

p53 signaling pathway

Oocyte meiosis

RIG-I-like receptor signaling pathway

Long-term potentiation

Parkinson's disease

Long-term depression

Purine metabolism

mTOR signaling pathway

Thyroid cancer

Epithelial cell signaling in Helicobacter pylori infection

Pathogenic Escherichia coli infection

Spliceosome

Basal cell carcinoma

Dilated cardiomyopathy

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

ECM-receptor interaction

NOD-like receptor signaling pathway

PPAR signaling pathway

Type II diabetes mellitus

Amyotrophic lateral sclerosis (ALS)

Oxidative phosphorylation

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Hypertrophic cardiomyopathy (HCM)

Systemic lupus erythematosus

Dorso-ventral axis formation

Metabolism of xenobiotics by cytochrome P450

Glutathione metabolism

Notch signaling pathway

Citrate cycle (TCA cycle)

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Antigen processing and presentation

Maturity onset diabetes of the young

Prion diseases

Viral myocarditis

Drug metabolism - cytochrome P450

Vibrio cholerae infection

Proteasome

Sphingolipid metabolism

Arginine and proline metabolism

Glycerophospholipid metabolism

Phosphatidylinositol signaling system

Pyruvate metabolism

Inositol phosphate metabolism

Lysine degradation

Retinol metabolism

Type I diabetes mellitus

Arachidonic acid metabolism

Complement and coagulation cascades

Pyrimidine metabolism

Allograft rejection

Autoimmune thyroid disease

Cysteine and methionine metabolism

Fatty acid metabolism

Mismatch repair

Olfactory transduction

Primary immunodeficiency

Regulation of autophagy

Tryptophan metabolism

ABC transporters

DNA replication

Drug metabolism - other enzymes

Androgen and estrogen metabolism

Fructose and mannose metabolism

N-Glycan biosynthesis

Nucleotide excision repair

Starch and sucrose metabolism

Valine

Alanine

Glycine

Graft-versus-host disease

Nicotinate and nicotinamide metabolism

Nitrogen metabolism

RNA degradation

Ribosome

Taste transduction

Tyrosine metabolism

aspartate and glutamate metabolism

serine and threonine metabolism

Base excision repair

Butanoate metabolism

SNARE interactions in vesicular transport

leucine and isoleucine degradation

Asthma

Galactose metabolism

Glycerolipid metabolism

Homologous recombination

Linoleic acid metabolism

Propanoate metabolism

Aminoacyl-tRNA biosynthesis

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Renin-angiotensin system

Selenoamino acid metabolism

Biosynthesis of unsaturated fatty acids

C21-Steroid hormone metabolism

Ether lipid metabolism

Pentose phosphate pathway

Phenylalanine metabolism

Porphyrin and chlorophyll metabolism

Steroid biosynthesis

Amino sugar and nucleotide sugar metabolism

Chondroitin sulfate biosynthesis

Heparan sulfate biosynthesis

Histidine metabolism

Keratan sulfate biosynthesis

Non-homologous end-joining

O-Glycan biosynthesis

alpha-Linolenic acid metabolism

Limonene and pinene degradation

One carbon pool by folate

Other glycan degradation

Primary bile acid biosynthesis

beta-Alanine metabolism

Ascorbate and aldarate metabolism

Glyoxylate and dicarboxylate metabolism

Methane metabolism

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

RNA polymerase

Sulfur metabolism

Synthesis and degradation of ketone bodies

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Folate biosynthesis

Riboflavin metabolism

Terpenoid backbone biosynthesis

leucine and isoleucine biosynthesis

Basal transcription factors

Circadian rhythm - mammal

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Phenylalanine

Taurine and hypotaurine metabolism

Thiamine metabolism

tyrosine and tryptophan biosynthesis

Biotin metabolism

Fatty acid biosynthesis

O-Mannosyl glycan biosynthesis

Protein export

Ubiquinone and other terpenoid-quinone biosynthesis

Vitamin B6 metabolism

Neomycin

1

Yes

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