cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

AKT1

IRAK

AKT3

ERK2

IFNAR2

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

TLR4

AKT2

B7-2

C FOS

C-JUN

CASPASE 8

CCL3

ERK1

FADD

IKB ALPHA

IKBKE

IKK BETA

IL1 BETA

IL12A

IL12B

IL6

IL8

INTERFERON ALPHA 2

IP10

IRAK4

IRF3

MAP3K8

MAPK11

MEK1

MEK2

MEK3

MEK4

MEK7

MYD88

NF-KB P65

NFKB1

PI 3 KINASE P85 ALPHA

PI 3 KINASE P85 BETA

PIK3CB

RIP

STAT1

TAK1

TBK1

TIRAP

TLR3

TLR8

TNF ALPHA

TOLLIP

TRAF3

TRAF6

Myc-DDK

Tag Free

pCMV6-Entry

pLenti-C-Myc-DDK

No

Yes

TrueORF Gold, TrueORF

TrueORF

Druggable Genome

Protein Kinase

Transcription Factors

Transmembrane

ES Cell Differentiation/IPS

Secreted Protein

Protease

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Focal adhesion

Cytokine-cytokine receptor interaction

Regulation of actin cytoskeleton

Neuroactive ligand-receptor interaction

Chemokine signaling pathway

Neurotrophin signaling pathway

Prostate cancer

T cell receptor signaling pathway

Jak-STAT signaling pathway

Colorectal cancer

ErbB signaling pathway

Insulin signaling pathway

Wnt signaling pathway

Calcium signaling pathway

Chronic myeloid leukemia

Endometrial cancer

Melanoma

Axon guidance

Pancreatic cancer

Renal cell carcinoma

Glioma

Natural killer cell mediated cytotoxicity

Toll-like receptor signaling pathway

Apoptosis

Endocytosis

GnRH signaling pathway

Melanogenesis

Acute myeloid leukemia

Non-small cell lung cancer

Small cell lung cancer

VEGF signaling pathway

B cell receptor signaling pathway

Cell cycle

Progesterone-mediated oocyte maturation

Alzheimer's disease

Fc epsilon RI signaling pathway

Gap junction

Adherens junction

Leukocyte transendothelial migration

Tight junction

Bladder cancer

Hematopoietic cell lineage

TGF-beta signaling pathway

Cell adhesion molecules (CAMs)

Fc gamma R-mediated phagocytosis

Long-term potentiation

Adipocytokine signaling pathway

Huntington's disease

Vascular smooth muscle contraction

p53 signaling pathway

Long-term depression

Oocyte meiosis

Ubiquitin mediated proteolysis

Thyroid cancer

Epithelial cell signaling in Helicobacter pylori infection

RIG-I-like receptor signaling pathway

mTOR signaling pathway

Basal cell carcinoma

Dilated cardiomyopathy

NOD-like receptor signaling pathway

Type II diabetes mellitus

Amyotrophic lateral sclerosis (ALS)

ECM-receptor interaction

Lysosome

Purine metabolism

Pathogenic Escherichia coli infection

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hedgehog signaling pathway

Hypertrophic cardiomyopathy (HCM)

Dorso-ventral axis formation

PPAR signaling pathway

Glycolysis / Gluconeogenesis

Parkinson's disease

Notch signaling pathway

Cytosolic DNA-sensing pathway

Prion diseases

Viral myocarditis

Metabolism of xenobiotics by cytochrome P450

Phosphatidylinositol signaling system

Antigen processing and presentation

Pyruvate metabolism

Inositol phosphate metabolism

Type I diabetes mellitus

Complement and coagulation cascades

Olfactory transduction

Primary immunodeficiency

Vibrio cholerae infection

ABC transporters

Allograft rejection

Autoimmune thyroid disease

Maturity onset diabetes of the young

Mismatch repair

Retinol metabolism

Arachidonic acid metabolism

Cardiac muscle contraction

Citrate cycle (TCA cycle)

Drug metabolism - cytochrome P450

Fructose and mannose metabolism

Sphingolipid metabolism

Arginine and proline metabolism

Cysteine and methionine metabolism

Lysine degradation

Regulation of autophagy

Systemic lupus erythematosus

Taste transduction

Base excision repair

Drug metabolism - other enzymes

Graft-versus-host disease

Starch and sucrose metabolism

Tyrosine metabolism

Androgen and estrogen metabolism

Galactose metabolism

Tryptophan metabolism

Valine

Asthma

Butanoate metabolism

Glutathione metabolism

Glycerophospholipid metabolism

Nucleotide excision repair

Pyrimidine metabolism

Renin-angiotensin system

C21-Steroid hormone metabolism

Fatty acid metabolism

Homologous recombination

Linoleic acid metabolism

Oxidative phosphorylation

Pentose phosphate pathway

Propanoate metabolism

Proteasome

Spliceosome

leucine and isoleucine degradation

DNA replication

Glycerolipid metabolism

Histidine metabolism

Non-homologous end-joining

Phenylalanine metabolism

Porphyrin and chlorophyll metabolism

Alanine

Aminoacyl-tRNA biosynthesis

Glycine

Nitrogen metabolism

SNARE interactions in vesicular transport

Selenoamino acid metabolism

Steroid biosynthesis

aspartate and glutamate metabolism

serine and threonine metabolism

Amino sugar and nucleotide sugar metabolism

Glycosaminoglycan degradation

Nicotinate and nicotinamide metabolism

Other glycan degradation

Synthesis and degradation of ketone bodies

Ascorbate and aldarate metabolism

Ether lipid metabolism

Folate biosynthesis

Glyoxylate and dicarboxylate metabolism

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

RNA degradation

Riboflavin metabolism

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

beta-Alanine metabolism

leucine and isoleucine biosynthesis

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

Circadian rhythm - mammal

Limonene and pinene degradation

Methane metabolism

O-Glycan biosynthesis

One carbon pool by folate

Pantothenate and CoA biosynthesis

Phenylalanine

Ribosome

Taurine and hypotaurine metabolism

Thiamine metabolism

tyrosine and tryptophan biosynthesis

Biotin metabolism

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

N-Glycan biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

1

Yes

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