cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

EVI1

IKK GAMMA

P16INK4A

P21 RAS

RUNX1

ACTIVIN A RECEPTOR TYPE IC

AKT1

AKT3

BCL X

C ABL

ERK2

GAB2

GRB2

KRAS

NFKB1

P21

PI 3 KINASE P55 GAMMA

PI 3 KINASE P85 ALPHA

PIK3R5

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

ACTIVIN A RECEPTOR TYPE IB

AKT2

B RAF

BAD

BCR

C-MYC

CBL

CBL C

CBLB

CDK4

CDK6

CRKL

CTBP1

CTBP2

CYCLIN D1

E2F1

E2F3

ERK1

HDAC1

HDAC2

IKB ALPHA

IKK ALPHA

IKK BETA

MDM2

MEK1

MEK2

NF-KB P65

NRAS

P27 KIP 1

P38

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAF1

SHC

SHC3

SHC4

SHP2

SMAD3

SMAD4

SOS1

STAT5A

STAT5B

TGF BETA 1

TGF BETA 3

Plasmids

Tag Free

Myc-DDK

mGFP

pLenti-C-Myc-DDK

No

Yes

LentiORF

TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Adult stem cells

Cancer stem cells

Induced pluripotent stem cells

Phosphatase

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Endocytosis

Calcium signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Leukocyte transendothelial migration

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Cell adhesion molecules (CAMs)

Ubiquitin mediated proteolysis

Alzheimer's disease

Axon guidance

Huntington's disease

Prostate cancer

ErbB signaling pathway

Progesterone-mediated oocyte maturation

Cell cycle

Melanogenesis

Tight junction

Colorectal cancer

Apoptosis

Oocyte meiosis

GnRH signaling pathway

Pancreatic cancer

Vascular smooth muscle contraction

Chronic myeloid leukemia

B cell receptor signaling pathway

Fc gamma R-mediated phagocytosis

Purine metabolism

Adherens junction

Melanoma

Small cell lung cancer

VEGF signaling pathway

Fc epsilon RI signaling pathway

Hematopoietic cell lineage

TGF-beta signaling pathway

Gap junction

Renal cell carcinoma

Lysosome

Glioma

RIG-I-like receptor signaling pathway

Adipocytokine signaling pathway

Dilated cardiomyopathy

Acute myeloid leukemia

Parkinson's disease

p53 signaling pathway

Long-term potentiation

NOD-like receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Non-small cell lung cancer

Endometrial cancer

Spliceosome

Antigen processing and presentation

Amyotrophic lateral sclerosis (ALS)

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Systemic lupus erythematosus

Type II diabetes mellitus

mTOR signaling pathway

Basal cell carcinoma

Hedgehog signaling pathway

Bladder cancer

ECM-receptor interaction

PPAR signaling pathway

Complement and coagulation cascades

Viral myocarditis

Oxidative phosphorylation

Cytosolic DNA-sensing pathway

Glycolysis / Gluconeogenesis

Pathogenic Escherichia coli infection

Arginine and proline metabolism

Phosphatidylinositol signaling system

Vibrio cholerae infection

Cardiac muscle contraction

Pyrimidine metabolism

Ribosome

Thyroid cancer

Glycerophospholipid metabolism

Autoimmune thyroid disease

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Olfactory transduction

Notch signaling pathway

Drug metabolism - cytochrome P450

Lysine degradation

Primary immunodeficiency

Type I diabetes mellitus

Valine

Arachidonic acid metabolism

Nucleotide excision repair

Prion diseases

Tryptophan metabolism

ABC transporters

Pyruvate metabolism

Regulation of autophagy

Sphingolipid metabolism

Starch and sucrose metabolism

Tyrosine metabolism

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Inositol phosphate metabolism

Maturity onset diabetes of the young

Glutathione metabolism

Graft-versus-host disease

N-Glycan biosynthesis

Proteasome

RNA degradation

Taste transduction

Allograft rejection

Citrate cycle (TCA cycle)

Cysteine and methionine metabolism

Fructose and mannose metabolism

Glycerolipid metabolism

Androgen and estrogen metabolism

Fatty acid metabolism

Dorso-ventral axis formation

Ether lipid metabolism

Base excision repair

Propanoate metabolism

Alanine

aspartate and glutamate metabolism

Galactose metabolism

SNARE interactions in vesicular transport

Glycine

Nitrogen metabolism

serine and threonine metabolism

Butanoate metabolism

DNA replication

Linoleic acid metabolism

Asthma

Glycosaminoglycan degradation

Glycosphingolipid biosynthesis - lacto and neolacto series

Histidine metabolism

Homologous recombination

Porphyrin and chlorophyll metabolism

O-Glycan biosynthesis

Pentose phosphate pathway

Phenylalanine metabolism

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

beta-Alanine metabolism

Aminoacyl-tRNA biosynthesis

Circadian rhythm - mammal

Mismatch repair

Heparan sulfate biosynthesis

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

Ascorbate and aldarate metabolism

One carbon pool by folate

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Other glycan degradation

Riboflavin metabolism

Selenoamino acid metabolism

Steroid biosynthesis

C21-Steroid hormone metabolism

Limonene and pinene degradation

RNA polymerase

Terpenoid backbone biosynthesis

Glyoxylate and dicarboxylate metabolism

Keratan sulfate biosynthesis

Folate biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Protein export

Methane metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Taurine and hypotaurine metabolism

Thiamine metabolism

leucine and isoleucine biosynthesis

Cyanoamino acid metabolism

Caffeine metabolism

Fatty acid biosynthesis

Synthesis and degradation of ketone bodies

Vitamin B6 metabolism

D-Glutamine and D-glutamate metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Neomycin

Puromycin

None

1

Yes

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