cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

EGFR

CACNA1G

CACNA1C

PTGER3

METABOTROPIC GLUTAMATE RECEPTOR 1

SERCA3

CACNA1A

HER2

NCX1

SLC8A3

5HT4 RECEPTOR

ADENOSINE RECEPTOR A2A

ALPHA 1A ADRENERGIC RECEPTOR

5HT7 RECEPTOR

ADCY4

ANGIOTENSIN II TYPE 1 RECEPTOR

CACNA1E

CYSLT1

NMDAR1

NMDAR2A

P2RX4

P2X2

P2X5

ADCY7

ATP2A1

ATP2B1

CACNA1B

CACNA1F

CACNA1I

CAV1.3

HRH1

HTR2C

NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA 7

RYANODINE RECEPTOR 3

SERCA2

TRPC1

5 HT 2A

ADCY9

ADENYLATE CYCLASE 1

ALPHA 1D ADRENERGIC RECEPTOR

ATP2B2

ATP2B3

ATP2B4

BDKRB1

BDKRB2

BETA 1 ADRENERGIC RECEPTOR

CACNA1H

CCKBR

ENDOTHELIN A RECEPTOR

ENDOTHELIN B RECEPTOR

EP1

ERBB 4

ERBB2

GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D

HRH2

HTR2B

ITPR3

LHCGR

METABOTROPIC GLUTAMATE RECEPTOR 5

NMDAR2C

P2X1

PROSTAGLANDIN F2 ALPHA RECEPTOR

THROMBOXANE A2 RECEPTOR

TurboGFP

Myc-DDK

DDK-His

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

LentiORF

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

Transmembrane

Protein Kinase

Secreted Protein

Ion Channels: Calcium

GPCR

ES Cell Differentiation/IPS

Adult stem cells

Cancer stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Transcription Factors

Ion Channels: ATP Receptors

Ion Channels: Glutamate Receptors

Phosphatase

Ion Channels: Sodium

Ion Channels: Cys-loop Receptors

Ion Channels: Other

Ion Channels: Transient receptor potential

Pathways in cancer

Metabolic pathways

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Endocytosis

Olfactory transduction

Calcium signaling pathway

MAPK signaling pathway

Thyroid cancer

Cell adhesion molecules (CAMs)

Adherens junction

Regulation of actin cytoskeleton

Melanoma

Focal adhesion

Prostate cancer

Alzheimer's disease

GnRH signaling pathway

Dilated cardiomyopathy

Colorectal cancer

Hematopoietic cell lineage

Vascular smooth muscle contraction

ABC transporters

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hypertrophic cardiomyopathy (HCM)

Type II diabetes mellitus

Axon guidance

Epithelial cell signaling in Helicobacter pylori infection

Gap junction

ErbB signaling pathway

Jak-STAT signaling pathway

Lysosome

Bladder cancer

Endometrial cancer

Natural killer cell mediated cytotoxicity

Pancreatic cancer

ECM-receptor interaction

Cardiac muscle contraction

Non-small cell lung cancer

Long-term potentiation

Glioma

Dorso-ventral axis formation

Chemokine signaling pathway

N-Glycan biosynthesis

Oxidative phosphorylation

Viral myocarditis

Drug metabolism - cytochrome P450

Huntington's disease

Adipocytokine signaling pathway

Metabolism of xenobiotics by cytochrome P450

Retinol metabolism

Parkinson's disease

TGF-beta signaling pathway

Long-term depression

PPAR signaling pathway

Purine metabolism

Starch and sucrose metabolism

Systemic lupus erythematosus

Glycosphingolipid biosynthesis - lacto and neolacto series

Taste transduction

Drug metabolism - other enzymes

Leukocyte transendothelial migration

Porphyrin and chlorophyll metabolism

Autoimmune thyroid disease

Toll-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Antigen processing and presentation

Androgen and estrogen metabolism

Arachidonic acid metabolism

SNARE interactions in vesicular transport

Keratan sulfate biosynthesis

Melanogenesis

Complement and coagulation cascades

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Graft-versus-host disease

Notch signaling pathway

Pentose and glucuronate interconversions

Prion diseases

Apoptosis

Sphingolipid metabolism

Type I diabetes mellitus

Allograft rejection

Fatty acid metabolism

Tight junction

Ascorbate and aldarate metabolism

Glycerophospholipid metabolism

T cell receptor signaling pathway

Neurotrophin signaling pathway

Primary immunodeficiency

Vibrio cholerae infection

p53 signaling pathway

Basal cell carcinoma

Fc gamma R-mediated phagocytosis

Chondroitin sulfate biosynthesis

Wnt signaling pathway

Cytosolic DNA-sensing pathway

Glutathione metabolism

Heparan sulfate biosynthesis

Oocyte meiosis

Progesterone-mediated oocyte maturation

Pyrimidine metabolism

Renal cell carcinoma

Tyrosine metabolism

Glycosphingolipid biosynthesis - ganglio series

O-Glycan biosynthesis

Pathogenic Escherichia coli infection

Ether lipid metabolism

Glycosphingolipid biosynthesis - globo series

Linoleic acid metabolism

Riboflavin metabolism

B cell receptor signaling pathway

Biosynthesis of unsaturated fatty acids

Glycerolipid metabolism

Renin-angiotensin system

Hedgehog signaling pathway

Insulin signaling pathway

Steroid biosynthesis

Asthma

Fc epsilon RI signaling pathway

Glycosaminoglycan degradation

Chronic myeloid leukemia

Primary bile acid biosynthesis

Galactose metabolism

Protein export

Small cell lung cancer

Amino sugar and nucleotide sugar metabolism

Cyanoamino acid metabolism

Inositol phosphate metabolism

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Ubiquitin mediated proteolysis

Citrate cycle (TCA cycle)

Nicotinate and nicotinamide metabolism

O-Mannosyl glycan biosynthesis

Phenylalanine metabolism

Phosphatidylinositol signaling system

alpha-Linolenic acid metabolism

Acute myeloid leukemia

Glycine

Glycolysis / Gluconeogenesis

Maturity onset diabetes of the young

Propanoate metabolism

RIG-I-like receptor signaling pathway

VEGF signaling pathway

serine and threonine metabolism

Base excision repair

C21-Steroid hormone metabolism

Caffeine metabolism

Pantothenate and CoA biosynthesis

Sulfur metabolism

Terpenoid backbone biosynthesis

Valine

beta-Alanine metabolism

leucine and isoleucine degradation

Arginine and proline metabolism

Fatty acid biosynthesis

Fatty acid elongation in mitochondria

Histidine metabolism

Limonene and pinene degradation

NOD-like receptor signaling pathway

Nitrogen metabolism

Other glycan degradation

Pyruvate metabolism

Tryptophan metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

1

Yes

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