cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

AKT1

KRAS

P53

B RAF

ERK2

IRAK

NF-KB P65

P21 RAS

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE P85 ALPHA

SORTILIN

14-3-3 BETA

14-3-3 EPSILON

14-3-3 ZETA

AKT2

AKT3

ATF 4

BAX

CAMK2A

CDC42

CRKL

ERK1

FOXO3

HRAS

IRAK2

IRS1

MEK1

MEKK1

MEKK3

NGF

NRAS

P73

P75 NGF RECEPTOR

PDK1

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

PLCG 2

RHOGDI

RIP2

SHP2

TRAF6

TRKA

TurboGFP

Myc-DDK

pCMV6-AC-GFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

TrueClone

TrueORF Gold, TrueORF

TrueORF

LentiORF

Druggable Genome

Protein Kinase

Transcription Factors

ES Cell Differentiation/IPS

Transmembrane

Stem cell - Pluripotency

Phosphatase

Secreted Protein

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Focal adhesion

Neuroactive ligand-receptor interaction

Prostate cancer

Endocytosis

Cytokine-cytokine receptor interaction

Colorectal cancer

Melanoma

Regulation of actin cytoskeleton

Chemokine signaling pathway

Calcium signaling pathway

ErbB signaling pathway

Endometrial cancer

Neurotrophin signaling pathway

Glioma

Jak-STAT signaling pathway

Pancreatic cancer

Renal cell carcinoma

Non-small cell lung cancer

Axon guidance

Chronic myeloid leukemia

T cell receptor signaling pathway

Insulin signaling pathway

Natural killer cell mediated cytotoxicity

Wnt signaling pathway

Acute myeloid leukemia

Bladder cancer

VEGF signaling pathway

Melanogenesis

Progesterone-mediated oocyte maturation

Gap junction

GnRH signaling pathway

Toll-like receptor signaling pathway

Adherens junction

Apoptosis

B cell receptor signaling pathway

Cell adhesion molecules (CAMs)

Fc epsilon RI signaling pathway

Small cell lung cancer

Leukocyte transendothelial migration

Cell cycle

Fc gamma R-mediated phagocytosis

Tight junction

Alzheimer's disease

Huntington's disease

Long-term potentiation

Adipocytokine signaling pathway

p53 signaling pathway

Thyroid cancer

Vascular smooth muscle contraction

mTOR signaling pathway

Hematopoietic cell lineage

Long-term depression

Type II diabetes mellitus

Epithelial cell signaling in Helicobacter pylori infection

Purine metabolism

Basal cell carcinoma

TGF-beta signaling pathway

Oocyte meiosis

Glutathione metabolism

Ubiquitin mediated proteolysis

Dorso-ventral axis formation

NOD-like receptor signaling pathway

Phosphatidylinositol signaling system

Notch signaling pathway

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

ECM-receptor interaction

Pathogenic Escherichia coli infection

Prion diseases

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Dilated cardiomyopathy

Lysosome

Viral myocarditis

ABC transporters

Hedgehog signaling pathway

Hypertrophic cardiomyopathy (HCM)

PPAR signaling pathway

Inositol phosphate metabolism

Parkinson's disease

Cytosolic DNA-sensing pathway

Maturity onset diabetes of the young

Sphingolipid metabolism

Arachidonic acid metabolism

Systemic lupus erythematosus

Antigen processing and presentation

Pyrimidine metabolism

Type I diabetes mellitus

Allograft rejection

Autoimmune thyroid disease

Citrate cycle (TCA cycle)

Glycolysis / Gluconeogenesis

Graft-versus-host disease

Metabolism of xenobiotics by cytochrome P450

Complement and coagulation cascades

Drug metabolism - cytochrome P450

Fatty acid metabolism

Glycerophospholipid metabolism

Lysine degradation

Cysteine and methionine metabolism

Homologous recombination

Pyruvate metabolism

Retinol metabolism

Spliceosome

Base excision repair

Glycerolipid metabolism

Mismatch repair

Arginine and proline metabolism

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Primary immunodeficiency

Starch and sucrose metabolism

Vibrio cholerae infection

Cardiac muscle contraction

Drug metabolism - other enzymes

Ether lipid metabolism

N-Glycan biosynthesis

RNA degradation

SNARE interactions in vesicular transport

Tryptophan metabolism

Tyrosine metabolism

Galactose metabolism

Nucleotide excision repair

Olfactory transduction

Oxidative phosphorylation

Ribosome

Valine

Alanine

Asthma

Biosynthesis of unsaturated fatty acids

DNA replication

Glycosaminoglycan degradation

Regulation of autophagy

Renin-angiotensin system

Taste transduction

aspartate and glutamate metabolism

Fructose and mannose metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Pantothenate and CoA biosynthesis

Pentose phosphate pathway

Phenylalanine metabolism

Propanoate metabolism

alpha-Linolenic acid metabolism

leucine and isoleucine biosynthesis

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Butanoate metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

D-Glutamine and D-glutamate metabolism

Glycine

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Nitrogen metabolism

O-Glycan biosynthesis

Other glycan degradation

RNA polymerase

serine and threonine metabolism

Caffeine metabolism

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

Folate biosynthesis

Histidine metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

Proteasome

Riboflavin metabolism

Selenoamino acid metabolism

Steroid biosynthesis

Sulfur metabolism

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Terpenoid backbone biosynthesis

beta-Alanine metabolism

Neomycin

1

Yes

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