cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

RRM2

CDK1

CYCLIN D3

CYCLIN E1

P21

PTEN

ATR

BAX

CASPASE 3

CD95

CDK4

CHK1

CHK2

CYCLIN D1

DR5

GADD45A

IGF1

MDM2

MDMX

P73

PERP

SKP2

TurboGFP

Myc-DDK

pCMV6-AC-GFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

TrueClone

TrueORF Gold, TrueORF

TrueORF

LentiORF

Druggable Genome

Stem cell - Pluripotency

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Phosphatase

Secreted Protein

Protease

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Focal adhesion

Neuroactive ligand-receptor interaction

Prostate cancer

Endocytosis

Cytokine-cytokine receptor interaction

Colorectal cancer

Melanoma

Chemokine signaling pathway

Regulation of actin cytoskeleton

Calcium signaling pathway

ErbB signaling pathway

Endometrial cancer

Neurotrophin signaling pathway

Glioma

Renal cell carcinoma

Jak-STAT signaling pathway

Pancreatic cancer

Axon guidance

Non-small cell lung cancer

Chronic myeloid leukemia

Insulin signaling pathway

T cell receptor signaling pathway

Natural killer cell mediated cytotoxicity

Wnt signaling pathway

Acute myeloid leukemia

Melanogenesis

Bladder cancer

VEGF signaling pathway

GnRH signaling pathway

Progesterone-mediated oocyte maturation

Gap junction

Adherens junction

Cell adhesion molecules (CAMs)

Toll-like receptor signaling pathway

Apoptosis

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Small cell lung cancer

Cell cycle

Leukocyte transendothelial migration

Fc gamma R-mediated phagocytosis

Tight junction

Alzheimer's disease

Long-term potentiation

p53 signaling pathway

Huntington's disease

Adipocytokine signaling pathway

Thyroid cancer

Vascular smooth muscle contraction

Type II diabetes mellitus

Long-term depression

mTOR signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Hematopoietic cell lineage

Purine metabolism

Basal cell carcinoma

Oocyte meiosis

TGF-beta signaling pathway

Dorso-ventral axis formation

Ubiquitin mediated proteolysis

Glutathione metabolism

NOD-like receptor signaling pathway

Notch signaling pathway

Phosphatidylinositol signaling system

Pathogenic Escherichia coli infection

Prion diseases

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Dilated cardiomyopathy

ECM-receptor interaction

Viral myocarditis

Lysosome

ABC transporters

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Hedgehog signaling pathway

Hypertrophic cardiomyopathy (HCM)

Inositol phosphate metabolism

PPAR signaling pathway

Parkinson's disease

Sphingolipid metabolism

Systemic lupus erythematosus

Arachidonic acid metabolism

Cytosolic DNA-sensing pathway

Maturity onset diabetes of the young

Pyrimidine metabolism

Allograft rejection

Antigen processing and presentation

Autoimmune thyroid disease

Glycolysis / Gluconeogenesis

Type I diabetes mellitus

Citrate cycle (TCA cycle)

Graft-versus-host disease

Metabolism of xenobiotics by cytochrome P450

Complement and coagulation cascades

Drug metabolism - cytochrome P450

Fatty acid metabolism

Lysine degradation

Spliceosome

Cysteine and methionine metabolism

Glycerophospholipid metabolism

Homologous recombination

Pyruvate metabolism

Retinol metabolism

Base excision repair

Mismatch repair

Primary immunodeficiency

Starch and sucrose metabolism

Vibrio cholerae infection

Glycerolipid metabolism

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Arginine and proline metabolism

Cardiac muscle contraction

Drug metabolism - other enzymes

Galactose metabolism

N-Glycan biosynthesis

Olfactory transduction

RNA degradation

SNARE interactions in vesicular transport

Tryptophan metabolism

Asthma

Ether lipid metabolism

Nucleotide excision repair

Oxidative phosphorylation

Ribosome

Taste transduction

Tyrosine metabolism

Valine

Alanine

Biosynthesis of unsaturated fatty acids

DNA replication

Glycosaminoglycan degradation

Regulation of autophagy

Renin-angiotensin system

aspartate and glutamate metabolism

Amino sugar and nucleotide sugar metabolism

Fructose and mannose metabolism

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Pantothenate and CoA biosynthesis

Pentose phosphate pathway

Propanoate metabolism

alpha-Linolenic acid metabolism

leucine and isoleucine biosynthesis

leucine and isoleucine degradation

Aminoacyl-tRNA biosynthesis

Androgen and estrogen metabolism

Butanoate metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

D-Glutamine and D-glutamate metabolism

Folate biosynthesis

Glycine

Glycosphingolipid biosynthesis - globo series

Nitrogen metabolism

O-Glycan biosynthesis

Other glycan degradation

Phenylalanine metabolism

RNA polymerase

serine and threonine metabolism

Caffeine metabolism

Chondroitin sulfate biosynthesis

Fatty acid biosynthesis

Histidine metabolism

Keratan sulfate biosynthesis

Limonene and pinene degradation

Lysine biosynthesis

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

Proteasome

Riboflavin metabolism

Selenoamino acid metabolism

Steroid biosynthesis

Sulfur metabolism

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Terpenoid backbone biosynthesis

beta-Alanine metabolism

Neomycin

1

Yes

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