cDNA Clones

cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

GLUCOCORTICOID RECEPTOR

MU OPIOID RECEPTOR

GROWTH HORMONE RECEPTOR

PARD3

PTGER3

LPAR6

METABOTROPIC GLUTAMATE RECEPTOR 4

LGR7

METABOTROPIC GLUTAMATE RECEPTOR 1

CANNABINOID RECEPTOR I

GRIA1

P2Y6

PROLACTIN RECEPTOR

VIP RECEPTOR 1

5HT4 RECEPTOR

ADENOSINE RECEPTOR A2A

ALPHA 1A ADRENERGIC RECEPTOR

CORTICOTROPIN RELEASING FACTOR RECEPTOR 2

CRF1

DOPAMINE RECEPTOR D3

GABRR1

GRIA4

LEPTIN RECEPTOR

P2RX4

PACAP RECEPTOR

5HT7 RECEPTOR

ANGIOTENSIN II TYPE 1 RECEPTOR

CYSLT1

GABA A RECEPTOR ALPHA 4

GABA A RECEPTOR BETA 3

GLUR3

GPR35

GROWTH HORMONE

NMDAR1

NMDAR2A

NPFFR2

P2RY5

P2X2

P2X5

THYROID HORMONE RECEPTOR ALPHA

ADENOSINE A3 RECEPTOR

ALPHA 1 GLYCINE RECEPTOR

CRLR

FPR1

FSH RECEPTOR

GABA A RECEPTOR GAMMA 2

GABA B RECEPTOR 1

GABRP

GLRB

GPR58

GRIK1

GRIK5

HRH1

HRH4

HTR2C

IONOTROPIC GLUTAMATE RECEPTOR 2

KA1

MCH2

PBR

PROSTAGLANDIN D2 RECEPTOR

SOMATOSTATIN RECEPTOR 5

TRYPSIN

TSH RECEPTOR

5 HT 2A

5 HT1F

ADENOSINE A1 RECEPTOR

ALPHA 1D ADRENERGIC RECEPTOR

ALPHA 2B ADRENERGIC RECEPTOR

AVPR V2

BDKRB1

BDKRB2

BETA 1 ADRENERGIC RECEPTOR

BOMBESIN RECEPTOR 3

CALCITONIN RECEPTOR

CATHEPSIN G

CCKBR

DOPAMINE D2 RECEPTOR

DOPAMINE RECEPTOR D4

EDG1

EDG8

ENDOTHELIN A RECEPTOR

ENDOTHELIN B RECEPTOR

EP1

EP4

FPR3

FPRL1

GABA A RECEPTOR ALPHA 6

GABA A RECEPTOR DELTA

GABRA2

GABRE

GABRG3

GABRR2

GALR2

GH2

GHRELIN RECEPTOR

GHRHR

GLP2R

GLUTAMATE RECEPTOR IONOTROPIC, NMDA 2D

GLYCINE RECEPTOR ALPHA 3

GNRHR

TurboGFP

Myc-DDK

pCMV6-Entry

pCMV6-AC-Myc-DDK

No

Yes

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

Transmembrane

GPCR

Ion Channels: Glutamate Receptors

Ion Channels: Cys-loop Receptors

Transcription Factors

Nuclear Hormone Receptor

Secreted Protein

Ion Channels: ATP Receptors

ES Cell Differentiation/IPS

Protease

Ion Channels: Sodium

Ion Channels: Transient receptor potential

Pathways in cancer

Metabolic pathways

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

MAPK signaling pathway

Pancreatic cancer

Prostate cancer

Melanoma

Focal adhesion

Ubiquitin mediated proteolysis

Regulation of actin cytoskeleton

Mismatch repair

B cell receptor signaling pathway

p53 signaling pathway

Glioma

Fc epsilon RI signaling pathway

Thyroid cancer

mTOR signaling pathway

Endocytosis

Non-small cell lung cancer

Chronic myeloid leukemia

Neurotrophin signaling pathway

Type II diabetes mellitus

ErbB signaling pathway

Bladder cancer

Chemokine signaling pathway

Calcium signaling pathway

Natural killer cell mediated cytotoxicity

Renal cell carcinoma

Wnt signaling pathway

Small cell lung cancer

Cytokine-cytokine receptor interaction

Tight junction

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Primary immunodeficiency

Neuroactive ligand-receptor interaction

Cell cycle

Apoptosis

Gap junction

Melanogenesis

Vascular smooth muscle contraction

GnRH signaling pathway

Homologous recombination

Long-term depression

Glycolysis / Gluconeogenesis

Huntington's disease

Acute myeloid leukemia

Adherens junction

Olfactory transduction

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

VEGF signaling pathway

Leukocyte transendothelial migration

Long-term potentiation

Maturity onset diabetes of the young

Galactose metabolism

Jak-STAT signaling pathway

Axon guidance

Dorso-ventral axis formation

Fc gamma R-mediated phagocytosis

Basal cell carcinoma

Phosphatidylinositol signaling system

Alzheimer's disease

Amyotrophic lateral sclerosis (ALS)

Notch signaling pathway

Toll-like receptor signaling pathway

Dilated cardiomyopathy

Purine metabolism

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Inositol phosphate metabolism

Adipocytokine signaling pathway

Cell adhesion molecules (CAMs)

Oocyte meiosis

Hypertrophic cardiomyopathy (HCM)

Vibrio cholerae infection

Viral myocarditis

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

ECM-receptor interaction

Taste transduction

Pyrimidine metabolism

Citrate cycle (TCA cycle)

Pathogenic Escherichia coli infection

Hematopoietic cell lineage

Parkinson's disease

PPAR signaling pathway

Oxidative phosphorylation

TGF-beta signaling pathway

Spliceosome

Cardiac muscle contraction

Nucleotide excision repair

Glycerophospholipid metabolism

NOD-like receptor signaling pathway

ABC transporters

Drug metabolism - cytochrome P450

RIG-I-like receptor signaling pathway

Metabolism of xenobiotics by cytochrome P450

Systemic lupus erythematosus

RNA degradation

Prion diseases

Glutathione metabolism

Retinol metabolism

Complement and coagulation cascades

Drug metabolism - other enzymes

Cytosolic DNA-sensing pathway

Arachidonic acid metabolism

N-Glycan biosynthesis

Lysine degradation

Arginine and proline metabolism

Ribosome

Tyrosine metabolism

Base excision repair

Antigen processing and presentation

Hedgehog signaling pathway

Pyruvate metabolism

Fatty acid metabolism

Glycerolipid metabolism

Sphingolipid metabolism

Cysteine and methionine metabolism

Autoimmune thyroid disease

Porphyrin and chlorophyll metabolism

Type I diabetes mellitus

Valine

DNA replication

Basal transcription factors

Tryptophan metabolism

RNA polymerase

Aminoacyl-tRNA biosynthesis

Proteasome

leucine and isoleucine degradation

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pentose and glucuronate interconversions

Phenylalanine metabolism

Propanoate metabolism

Allograft rejection

Histidine metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Nitrogen metabolism

Selenoamino acid metabolism

Ether lipid metabolism

Glycine

Steroid biosynthesis

serine and threonine metabolism

SNARE interactions in vesicular transport

Ascorbate and aldarate metabolism

Glycosaminoglycan degradation

Keratan sulfate biosynthesis

Alanine

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

One carbon pool by folate

aspartate and glutamate metabolism

Pantothenate and CoA biosynthesis

Pentose phosphate pathway

Nicotinate and nicotinamide metabolism

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

Regulation of autophagy

Biosynthesis of unsaturated fatty acids

Butanoate metabolism

Cyanoamino acid metabolism

Riboflavin metabolism

Circadian rhythm - mammal

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Protein export

Asthma

Glycosphingolipid biosynthesis - ganglio series

Other glycan degradation

beta-Alanine metabolism

Taurine and hypotaurine metabolism

Limonene and pinene degradation

O-Glycan biosynthesis

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

Terpenoid backbone biosynthesis

Lysine biosynthesis

Thiamine metabolism

leucine and isoleucine biosynthesis

Fatty acid biosynthesis

Folate biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

Sulfur metabolism

Lipoic acid metabolism

Methane metabolism

Phenylalanine

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

C21-Steroid hormone metabolism

Vitamin B6 metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

1

Yes

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