cDNA Clones

cDNA Clones

Mutant ORF Clones

Expression Plasmids

Human

CTNNB1

BETA CATENIN

P53

PTCH1

TCF7L2

AXIN1

TCF7

AXIN2

APC

FZD3

GLI1

STK36

DISHEVELLED 3

FRIZZLED 2

FRIZZLED 6

FRIZZLED 7

FRIZZLED 8

FRIZZLED HOMOLOG 1

GLI3

LEF1

PTCH2

SUPPRESSOR OF FUSED

TCF7L1

WNT10B

WNT5A

Myc-DDK

pCMV6-Entry

pCMV6-AC-Myc-DDK

pCMV6-AN-Myc-DDK

Yes

No

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

ES Cell Differentiation/IPS

Transcription Factors

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Secreted Protein

Adult stem cells

GPCR

Induced pluripotent stem cells

Embryonic stem cells

Protein Kinase

Stem cell relevant signaling - DSL/Notch pathway

Pathways in cancer

Colorectal cancer

Insulin signaling pathway

Metabolic pathways

Endometrial cancer

Pancreatic cancer

MAPK signaling pathway

Focal adhesion

Ubiquitin mediated proteolysis

Mismatch repair

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Prostate cancer

Regulation of actin cytoskeleton

mTOR signaling pathway

Melanoma

Type II diabetes mellitus

ErbB signaling pathway

Glioma

p53 signaling pathway

Endocytosis

Thyroid cancer

Chemokine signaling pathway

Non-small cell lung cancer

Renal cell carcinoma

Calcium signaling pathway

Natural killer cell mediated cytotoxicity

Chronic myeloid leukemia

Neurotrophin signaling pathway

Cytokine-cytokine receptor interaction

Progesterone-mediated oocyte maturation

T cell receptor signaling pathway

Primary immunodeficiency

Gap junction

Neuroactive ligand-receptor interaction

Bladder cancer

Melanogenesis

GnRH signaling pathway

Long-term depression

Homologous recombination

VEGF signaling pathway

Glycolysis / Gluconeogenesis

Vascular smooth muscle contraction

Acute myeloid leukemia

Adherens junction

Starch and sucrose metabolism

Long-term potentiation

Maturity onset diabetes of the young

Galactose metabolism

Tight junction

Amino sugar and nucleotide sugar metabolism

Jak-STAT signaling pathway

Leukocyte transendothelial migration

Dorso-ventral axis formation

Small cell lung cancer

Wnt signaling pathway

Axon guidance

Phosphatidylinositol signaling system

Fc gamma R-mediated phagocytosis

Apoptosis

Toll-like receptor signaling pathway

Notch signaling pathway

Cell cycle

Dilated cardiomyopathy

Inositol phosphate metabolism

Adipocytokine signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Alzheimer's disease

Oocyte meiosis

Purine metabolism

Cell adhesion molecules (CAMs)

Basal cell carcinoma

Hypertrophic cardiomyopathy (HCM)

Taste transduction

Hematopoietic cell lineage

Vibrio cholerae infection

Epithelial cell signaling in Helicobacter pylori infection

Olfactory transduction

ECM-receptor interaction

Pathogenic Escherichia coli infection

Huntington's disease

Amyotrophic lateral sclerosis (ALS)

Citrate cycle (TCA cycle)

PPAR signaling pathway

TGF-beta signaling pathway

NOD-like receptor signaling pathway

Viral myocarditis

ABC transporters

Lysosome

Nucleotide excision repair

Cardiac muscle contraction

Prion diseases

Complement and coagulation cascades

RIG-I-like receptor signaling pathway

Glycerophospholipid metabolism

Base excision repair

Hedgehog signaling pathway

Drug metabolism - cytochrome P450

Pyrimidine metabolism

Metabolism of xenobiotics by cytochrome P450

Parkinson's disease

Retinol metabolism

Tyrosine metabolism

Lysine degradation

Arginine and proline metabolism

Arachidonic acid metabolism

Cytosolic DNA-sensing pathway

Drug metabolism - other enzymes

Glycerolipid metabolism

Cysteine and methionine metabolism

Fatty acid metabolism

Valine

Systemic lupus erythematosus

Autoimmune thyroid disease

Pyruvate metabolism

Histidine metabolism

Type I diabetes mellitus

leucine and isoleucine degradation

Antigen processing and presentation

Sphingolipid metabolism

Tryptophan metabolism

Glutathione metabolism

Propanoate metabolism

Nitrogen metabolism

Phenylalanine metabolism

Steroid biosynthesis

SNARE interactions in vesicular transport

Allograft rejection

Fructose and mannose metabolism

Proteasome

Aminoacyl-tRNA biosynthesis

Non-homologous end-joining

Riboflavin metabolism

DNA replication

Oxidative phosphorylation

Androgen and estrogen metabolism

Circadian rhythm - mammal

Graft-versus-host disease

Linoleic acid metabolism

Selenoamino acid metabolism

Alanine

Butanoate metabolism

Pentose phosphate pathway

Renin-angiotensin system

Spliceosome

aspartate and glutamate metabolism

Ether lipid metabolism

Glycine

Glycosaminoglycan degradation

Other glycan degradation

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

beta-Alanine metabolism

serine and threonine metabolism

N-Glycan biosynthesis

Regulation of autophagy

Pantothenate and CoA biosynthesis

Fatty acid biosynthesis

One carbon pool by folate

Protein export

RNA degradation

Terpenoid backbone biosynthesis

leucine and isoleucine biosynthesis

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - ganglio series

Nicotinate and nicotinamide metabolism

Pentose and glucuronate interconversions

Asthma

Basal transcription factors

Limonene and pinene degradation

alpha-Linolenic acid metabolism

Biotin metabolism

Folate biosynthesis

Glyoxylate and dicarboxylate metabolism

Ribosome

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

C21-Steroid hormone metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - globo series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Lysine biosynthesis

Neomycin

1

Yes

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