cDNA Clones

cDNA Clones

Expression Plasmids

Human

WNT2B

AXIN 2

BETA CATENIN

BMP4

DVL1

FRIZZLED 7

GLI1

GSK3 BETA

LEF1

P53

SONIC HEDGEHOG

TCF7

TCF7L2

WNT10B

WNT16

WNT3

WNT4

WNT5A

WNT7A

WNT7B

WNT9B

Plasmids

Myc-DDK

pCMV6-Entry

pCMV6-AC-Myc-DDK

pCMV6-AC-GFP

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pCMV6-XL5

pCMV6-XL4

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP

pCMV6-AC

pCMV6-XL6

No

LentiORF

Druggable Genome

Secreted Protein

ES Cell Differentiation/IPS

Transmembrane

Transcription Factors

Adult stem cells

Cancer stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - Wnt Signaling pathway

Protein Kinase

Stem cell - Pluripotency

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Pathways in cancer

Metabolic pathways

Cytokine-cytokine receptor interaction

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Prostate cancer

Jak-STAT signaling pathway

Cell adhesion molecules (CAMs)

Natural killer cell mediated cytotoxicity

Cell cycle

Wnt signaling pathway

Melanoma

Insulin signaling pathway

Chronic myeloid leukemia

Endocytosis

Hematopoietic cell lineage

Pancreatic cancer

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Calcium signaling pathway

ErbB signaling pathway

Colorectal cancer

Leukocyte transendothelial migration

TGF-beta signaling pathway

Tight junction

Glioma

Small cell lung cancer

Renal cell carcinoma

Bladder cancer

Ubiquitin mediated proteolysis

Acute myeloid leukemia

Apoptosis

Axon guidance

Alzheimer's disease

B cell receptor signaling pathway

Adherens junction

p53 signaling pathway

Melanogenesis

Endometrial cancer

NOD-like receptor signaling pathway

Non-small cell lung cancer

Oocyte meiosis

Fc gamma R-mediated phagocytosis

VEGF signaling pathway

Adipocytokine signaling pathway

Fc epsilon RI signaling pathway

Progesterone-mediated oocyte maturation

Antigen processing and presentation

Gap junction

GnRH signaling pathway

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Huntington's disease

PPAR signaling pathway

Systemic lupus erythematosus

mTOR signaling pathway

Amyotrophic lateral sclerosis (ALS)

Long-term potentiation

Vascular smooth muscle contraction

Cytosolic DNA-sensing pathway

Epithelial cell signaling in Helicobacter pylori infection

Hypertrophic cardiomyopathy (HCM)

Long-term depression

Dilated cardiomyopathy

Lysosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Basal cell carcinoma

Graft-versus-host disease

Thyroid cancer

Viral myocarditis

Hedgehog signaling pathway

Pathogenic Escherichia coli infection

Primary immunodeficiency

Type II diabetes mellitus

Parkinson's disease

Purine metabolism

Autoimmune thyroid disease

Glycolysis / Gluconeogenesis

Complement and coagulation cascades

Allograft rejection

Pyruvate metabolism

Type I diabetes mellitus

Arginine and proline metabolism

Maturity onset diabetes of the young

Notch signaling pathway

Proteasome

Regulation of autophagy

Sphingolipid metabolism

Nucleotide excision repair

Base excision repair

Citrate cycle (TCA cycle)

Spliceosome

Cysteine and methionine metabolism

Dorso-ventral axis formation

Metabolism of xenobiotics by cytochrome P450

Phosphatidylinositol signaling system

Prion diseases

Retinol metabolism

Tryptophan metabolism

Vibrio cholerae infection

Arachidonic acid metabolism

Glycerolipid metabolism

Glycosaminoglycan degradation

Lysine degradation

ABC transporters

Asthma

Glycerophospholipid metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Pyrimidine metabolism

Ribosome

Tyrosine metabolism

Valine

Drug metabolism - cytochrome P450

Fatty acid metabolism

Galactose metabolism

Glutathione metabolism

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Butanoate metabolism

Circadian rhythm - mammal

Fructose and mannose metabolism

Heparan sulfate biosynthesis

Homologous recombination

Linoleic acid metabolism

Nicotinate and nicotinamide metabolism

Other glycan degradation

RNA degradation

leucine and isoleucine degradation

Cardiac muscle contraction

Folate biosynthesis

Glycosphingolipid biosynthesis - globo series

Mismatch repair

Oxidative phosphorylation

Renin-angiotensin system

DNA replication

Drug metabolism - other enzymes

Ether lipid metabolism

Glycine

Inositol phosphate metabolism

SNARE interactions in vesicular transport

beta-Alanine metabolism

serine and threonine metabolism

Alanine

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

N-Glycan biosynthesis

O-Glycan biosynthesis

Phenylalanine metabolism

Steroid biosynthesis

Taste transduction

aspartate and glutamate metabolism

Aminoacyl-tRNA biosynthesis

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Histidine metabolism

Keratan sulfate biosynthesis

Methane metabolism

Nitrogen metabolism

Olfactory transduction

Pentose phosphate pathway

alpha-Linolenic acid metabolism

leucine and isoleucine biosynthesis

Androgen and estrogen metabolism

C21-Steroid hormone metabolism

Non-homologous end-joining

One carbon pool by folate

Pantothenate and CoA biosynthesis

Pentose and glucuronate interconversions

Porphyrin and chlorophyll metabolism

Riboflavin metabolism

Selenoamino acid metabolism

Sulfur metabolism

Cyanoamino acid metabolism

D-Arginine and D-ornithine metabolism

Fatty acid elongation in mitochondria

Phenylalanine

Primary bile acid biosynthesis

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Puromycin

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