活动过滤器
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Species
Target Symbol
- BDNF (9)
- CD44 (8)
- BIN1 (7)
- HNF 4 ALPHA (7)
- VEGFA (7)
- CD46 (6)
- CEACAM1 (6)
- EGFR (6)
- MAX (6)
- MYELIN BASIC PROTEIN (6)
- NRG2 (6)
- NUMB (6)
- TAU (6)
- TFEB (6)
- ACRV1 (5)
- ALKALINE PHOSPHATASE (5)
- CCR2 (5)
- CONSTITUTIVE ANDROSTANE RECEPTOR (5)
- EZH2 (5)
- FGFR1 (5)
- GLUCOCORTICOID RECEPTOR (5)
- IGF2 (5)
- IRF3 (5)
- MYOSIN (5)
- RIBONUCLEASE INHIBITOR (5)
- SIRT3 (5)
- SPHK1 (5)
- TGIF (5)
- TSPAN4 (5)
- 5HT4 RECEPTOR (4)
- ALPHA 1 ANTITRYPSIN (4)
- ALPHA TUBULIN (4)
- ANGIOTENSIN II TYPE 1 RECEPTOR (4)
- AURORA A (4)
- AUTS2 (4)
- BAIAP2 (4)
- BAX (4)
- BID (4)
- BMP4 (4)
- CACNB3 (4)
- CALCIPRESSIN 1 (4)
- CAMK2B (4)
- CAMK2D (4)
- CAMK2G (4)
- CASPASE 8 (4)
- CD84 (4)
- CD8A (4)
- CD95 (4)
- CDC42 (4)
- CLATHRIN LIGHT CHAIN (4)
- CREM (4)
- DCAMKL1 (4)
- DDIT3 (4)
- DENND1B (4)
- DNMT3A (4)
- ETS1 (4)
- FCGRT (4)
- FGF14 (4)
- FGFR2 (4)
- FOXM1 (4)
- FOXP2 (4)
- FYN (4)
- GAP43 (4)
- GDNF (4)
- HGF (4)
- HSD17B13 (4)
- IGF1 (4)
- IL15RA (4)
- IL1RA (4)
- IL32 (4)
- INPP4A (4)
- IRF5 (4)
- KCNK10 (4)
- LAIR1 (4)
- LAMP2 (4)
- LEF1 (4)
- LST1 (4)
- LY108 (4)
- MEIS2 (4)
- MEST (4)
- MFGE8 (4)
- MS4A6A (4)
- NDRG2 (4)
- NF2 (4)
- NFYA (4)
- NME2 (4)
- NR2F2 (4)
- NRP2 (4)
- OPA1 (4)
- P38 (4)
- PITX2 (4)
- PPAR GAMMA (4)
- PPM1B (4)
- PRKACB (4)
- PRKAR1B (4)
- QK1 (4)
- RAB23 (4)
- RGS3 (4)
- RO60 (4)
- RUNX2 (4)
Mutants
Brands
Families
- Druggable Genome (6374)
- Transmembrane (3902)
- Transcription Factors (1559)
- Secreted Protein (1129)
- Protein Kinase (520)
- ES Cell Differentiation/IPS (421)
- Protease (390)
- GPCR (343)
- Stem cell - Pluripotency (312)
- Phosphatase (165)
- Ion Channels: Other (130)
- Adult stem cells (108)
- Embryonic stem cells (86)
- Nuclear Hormone Receptor (82)
- Ion Channels: Potassium (78)
- Cancer stem cells (63)
- Induced pluripotent stem cells (48)
- P450 (48)
- Ion Channels: Cys-loop Receptors (44)
- Ion Channels: Transient receptor potential (29)
- Stem cell relevant signaling - JAK/STAT signaling pathway (29)
- Stem cell relevant signaling - DSL/Notch pathway (27)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (27)
- Stem cell relevant signaling - Wnt Signaling pathway (23)
- Ion Channels: Glutamate Receptors (18)
- Ion Channels: Sodium (15)
- Ion Channels: ATP Receptors (9)
- Ion Channels: Cyclic nucleotide gated (9)
- Ion Channels: Calcium (7)
Pathways
- Metabolic pathways (957)
- Pathways in cancer (428)
- MAPK signaling pathway (335)
- Cytokine-cytokine receptor interaction (301)
- Neuroactive ligand-receptor interaction (297)
- Regulation of actin cytoskeleton (223)
- Focal adhesion (219)
- Chemokine signaling pathway (205)
- Endocytosis (195)
- Calcium signaling pathway (187)
- Jak-STAT signaling pathway (182)
- Wnt signaling pathway (179)
- Huntington's disease (177)
- Neurotrophin signaling pathway (175)
- Alzheimer's disease (173)
- Insulin signaling pathway (156)
- Natural killer cell mediated cytotoxicity (153)
- Purine metabolism (144)
- Cell adhesion molecules (CAMs) (143)
- Ubiquitin mediated proteolysis (142)
- T cell receptor signaling pathway (136)
- Cell cycle (133)
- Oocyte meiosis (132)
- Toll-like receptor signaling pathway (132)
- Apoptosis (131)
- Axon guidance (131)
- Leukocyte transendothelial migration (127)
- Melanogenesis (127)
- Progesterone-mediated oocyte maturation (127)
- Tight junction (127)
- Prostate cancer (125)
- ErbB signaling pathway (124)
- GnRH signaling pathway (122)
- Colorectal cancer (117)
- Systemic lupus erythematosus (116)
- Vascular smooth muscle contraction (115)
- Parkinson's disease (113)
- Hematopoietic cell lineage (111)
- Fc gamma R-mediated phagocytosis (109)
- Pancreatic cancer (107)
- Gap junction (104)
- Spliceosome (104)
- Lysosome (102)
- Oxidative phosphorylation (102)
- Renal cell carcinoma (100)
- Adherens junction (99)
- Dilated cardiomyopathy (97)
- TGF-beta signaling pathway (97)
- VEGF signaling pathway (97)
- p53 signaling pathway (96)
- B cell receptor signaling pathway (95)
- Chronic myeloid leukemia (95)
- Small cell lung cancer (95)
- Fc epsilon RI signaling pathway (94)
- Melanoma (94)
- Antigen processing and presentation (92)
- Pyrimidine metabolism (90)
- Adipocytokine signaling pathway (89)
- Hypertrophic cardiomyopathy (HCM) (89)
- Olfactory transduction (89)
- Long-term potentiation (87)
- Glioma (85)
- Acute myeloid leukemia (84)
- Epithelial cell signaling in Helicobacter pylori infection (83)
- NOD-like receptor signaling pathway (82)
- PPAR signaling pathway (81)
- RIG-I-like receptor signaling pathway (80)
- Long-term depression (79)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (78)
- ECM-receptor interaction (76)
- Endometrial cancer (74)
- Complement and coagulation cascades (73)
- Amyotrophic lateral sclerosis (ALS) (72)
- Cardiac muscle contraction (70)
- Non-small cell lung cancer (70)
- Viral myocarditis (70)
- Pathogenic Escherichia coli infection (66)
- mTOR signaling pathway (66)
- Basal cell carcinoma (65)
- Ribosome (64)
- Glycolysis / Gluconeogenesis (63)
- Phosphatidylinositol signaling system (63)
- Type II diabetes mellitus (61)
- Cytosolic DNA-sensing pathway (60)
- Hedgehog signaling pathway (60)
- Glycerophospholipid metabolism (59)
- Vibrio cholerae infection (58)
- Bladder cancer (55)
- Autoimmune thyroid disease (54)
- Arachidonic acid metabolism (52)
- Drug metabolism - cytochrome P450 (51)
- Type I diabetes mellitus (51)
- Arginine and proline metabolism (49)
- Graft-versus-host disease (49)
- Metabolism of xenobiotics by cytochrome P450 (48)
- Notch signaling pathway (48)
- RNA degradation (48)
- Valine (48)
- Inositol phosphate metabolism (47)
- Thyroid cancer (47)
- Glutathione metabolism (46)
- Taste transduction (46)
- Allograft rejection (44)
- Proteasome (43)
- Retinol metabolism (43)
- SNARE interactions in vesicular transport (41)
- leucine and isoleucine degradation (41)
- Fatty acid metabolism (40)
- Nucleotide excision repair (40)
- Primary immunodeficiency (40)
- Tyrosine metabolism (40)
- Amino sugar and nucleotide sugar metabolism (39)
- Cysteine and methionine metabolism (39)
- Glycerolipid metabolism (39)
- Prion diseases (39)
- Pyruvate metabolism (39)
- N-Glycan biosynthesis (37)
- Drug metabolism - other enzymes (36)
- Fructose and mannose metabolism (36)
- Maturity onset diabetes of the young (36)
- Sphingolipid metabolism (36)
- Base excision repair (34)
- Ether lipid metabolism (34)
- Tryptophan metabolism (34)
- Alanine (33)
- Aminoacyl-tRNA biosynthesis (33)
- Lysine degradation (33)
- Starch and sucrose metabolism (33)
- aspartate and glutamate metabolism (33)
- ABC transporters (32)
- Androgen and estrogen metabolism (30)
- Dorso-ventral axis formation (30)
- Asthma (29)
- Regulation of autophagy (29)
- Nicotinate and nicotinamide metabolism (28)
- Galactose metabolism (27)
- Glycosphingolipid biosynthesis - lacto and neolacto series (27)
- Propanoate metabolism (27)
- Glycine (26)
- Homologous recombination (26)
- Pentose phosphate pathway (26)
- serine and threonine metabolism (26)
- Butanoate metabolism (25)
- Citrate cycle (TCA cycle) (25)
- DNA replication (25)
- RNA polymerase (25)
- Histidine metabolism (24)
- Linoleic acid metabolism (23)
- Porphyrin and chlorophyll metabolism (23)
- Selenoamino acid metabolism (23)
- Basal transcription factors (22)
- Glycosaminoglycan degradation (21)
- Heparan sulfate biosynthesis (21)
- O-Glycan biosynthesis (21)
- Phenylalanine metabolism (20)
- beta-Alanine metabolism (20)
- Renin-angiotensin system (19)
- Mismatch repair (18)
- Nitrogen metabolism (18)
- Riboflavin metabolism (17)
- Glycosphingolipid biosynthesis - globo series (16)
- Biosynthesis of unsaturated fatty acids (15)
- Chondroitin sulfate biosynthesis (15)
- Glycosphingolipid biosynthesis - ganglio series (15)
- Keratan sulfate biosynthesis (15)
- Non-homologous end-joining (15)
- Primary bile acid biosynthesis (15)
- Circadian rhythm - mammal (14)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (14)
- Steroid biosynthesis (14)
- Terpenoid backbone biosynthesis (14)
- alpha-Linolenic acid metabolism (14)
- C21-Steroid hormone metabolism (13)
- Other glycan degradation (13)
- Pantothenate and CoA biosynthesis (13)
- Sulfur metabolism (13)
- Glyoxylate and dicarboxylate metabolism (12)
- One carbon pool by folate (12)
- Limonene and pinene degradation (11)
- Pentose and glucuronate interconversions (11)
- Folate biosynthesis (10)
- Ascorbate and aldarate metabolism (9)
- Taurine and hypotaurine metabolism (9)
- leucine and isoleucine biosynthesis (9)
- Cyanoamino acid metabolism (8)
- Synthesis and degradation of ketone bodies (8)
- Caffeine metabolism (7)
- Fatty acid elongation in mitochondria (7)
- Thiamine metabolism (7)
- Methane metabolism (6)
- Protein export (6)
- Fatty acid biosynthesis (5)
- Lipoic acid metabolism (5)
- Ubiquinone and other terpenoid-quinone biosynthesis (5)
- Vitamin B6 metabolism (5)
- Phenylalanine (4)
- tyrosine and tryptophan biosynthesis (4)
- D-Glutamine and D-glutamate metabolism (3)
- Biotin metabolism (2)
- O-Mannosyl glycan biosynthesis (2)
- Lysine biosynthesis (1)