cDNA Clones

cDNA Clones

Expression Plasmids

Human

AKT1

PPAR DELTA

KRAS

LEF1

P21 RAS

PI 3 KINASE P85 ALPHA

SKP2

SPI1

STAT3

TCF7

A RAF

AKT2

AKT3

B RAF

C-MYC

CEBP ALPHA

CYCLIN D1

ERK1

GRB2

IKK BETA

MEK1

MEK2

NF-KB P65

NFKB1

NRAS

P70 S6 KINASE BETA

PIK3CD

PIM1

PLZF

RAF1

RUNX1

S6K1

STAT5A

STAT5B

BAD

BMP2

ERK2

FLT3

IKK ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PIK3CB

PIM2

RETINOIC ACID RECEPTOR ALPHA

TCF7L2

Plasmids

mGFP

Myc-DDK

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK-P2A-Puro

No

LentiORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Stem cell relevant signaling - JAK/STAT signaling pathway

Nuclear Hormone Receptor

Adult stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Transmembrane

Cancer stem cells

Secreted Protein

Pathways in cancer

Metabolic pathways

Cytokine-cytokine receptor interaction

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Neurotrophin signaling pathway

Chemokine signaling pathway

Jak-STAT signaling pathway

Prostate cancer

Cell adhesion molecules (CAMs)

Natural killer cell mediated cytotoxicity

Endocytosis

Insulin signaling pathway

Wnt signaling pathway

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Cell cycle

Melanoma

Chronic myeloid leukemia

Calcium signaling pathway

Pancreatic cancer

Colorectal cancer

Hematopoietic cell lineage

ErbB signaling pathway

Leukocyte transendothelial migration

Tight junction

Small cell lung cancer

Apoptosis

Axon guidance

Alzheimer's disease

Glioma

TGF-beta signaling pathway

Renal cell carcinoma

B cell receptor signaling pathway

Acute myeloid leukemia

Melanogenesis

Ubiquitin mediated proteolysis

Adherens junction

Adipocytokine signaling pathway

Bladder cancer

Fc epsilon RI signaling pathway

Oocyte meiosis

Progesterone-mediated oocyte maturation

Non-small cell lung cancer

Endometrial cancer

Fc gamma R-mediated phagocytosis

p53 signaling pathway

VEGF signaling pathway

Huntington's disease

Gap junction

GnRH signaling pathway

NOD-like receptor signaling pathway

Antigen processing and presentation

Vascular smooth muscle contraction

RIG-I-like receptor signaling pathway

ECM-receptor interaction

Hypertrophic cardiomyopathy (HCM)

Dilated cardiomyopathy

PPAR signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

mTOR signaling pathway

Amyotrophic lateral sclerosis (ALS)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Long-term depression

Long-term potentiation

Systemic lupus erythematosus

Basal cell carcinoma

Type II diabetes mellitus

Cytosolic DNA-sensing pathway

Lysosome

Thyroid cancer

Hedgehog signaling pathway

Parkinson's disease

Viral myocarditis

Pathogenic Escherichia coli infection

Graft-versus-host disease

Purine metabolism

Glycolysis / Gluconeogenesis

Maturity onset diabetes of the young

Autoimmune thyroid disease

Primary immunodeficiency

Allograft rejection

Complement and coagulation cascades

Type I diabetes mellitus

Arginine and proline metabolism

Phosphatidylinositol signaling system

Notch signaling pathway

Metabolism of xenobiotics by cytochrome P450

Pyruvate metabolism

Spliceosome

Nucleotide excision repair

Glycerolipid metabolism

Prion diseases

Vibrio cholerae infection

Arachidonic acid metabolism

Proteasome

Sphingolipid metabolism

Glycerophospholipid metabolism

Regulation of autophagy

Retinol metabolism

Tryptophan metabolism

ABC transporters

Citrate cycle (TCA cycle)

Base excision repair

Lysine degradation

Dorso-ventral axis formation

Drug metabolism - cytochrome P450

Tyrosine metabolism

Asthma

Cysteine and methionine metabolism

Valine

Pyrimidine metabolism

Ribosome

Fatty acid metabolism

Glutathione metabolism

Homologous recombination

Linoleic acid metabolism

Oxidative phosphorylation

Cardiac muscle contraction

Glycosaminoglycan degradation

Propanoate metabolism

Inositol phosphate metabolism

RNA degradation

Butanoate metabolism

Circadian rhythm - mammal

Galactose metabolism

Mismatch repair

Starch and sucrose metabolism

leucine and isoleucine degradation

Fructose and mannose metabolism

Glycine

SNARE interactions in vesicular transport

serine and threonine metabolism

DNA replication

Drug metabolism - other enzymes

Nicotinate and nicotinamide metabolism

O-Glycan biosynthesis

Olfactory transduction

Other glycan degradation

Ether lipid metabolism

Renin-angiotensin system

Amino sugar and nucleotide sugar metabolism

beta-Alanine metabolism

Alanine

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Nitrogen metabolism

Phenylalanine metabolism

Taste transduction

aspartate and glutamate metabolism

Folate biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Heparan sulfate biosynthesis

Non-homologous end-joining

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

C21-Steroid hormone metabolism

Glyoxylate and dicarboxylate metabolism

Methane metabolism

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Histidine metabolism

N-Glycan biosynthesis

One carbon pool by folate

alpha-Linolenic acid metabolism

Pentose phosphate pathway

Riboflavin metabolism

leucine and isoleucine biosynthesis

Keratan sulfate biosynthesis

Pentose and glucuronate interconversions

Porphyrin and chlorophyll metabolism

Cyanoamino acid metabolism

Pantothenate and CoA biosynthesis

Primary bile acid biosynthesis

Selenoamino acid metabolism

Synthesis and degradation of ketone bodies

Protein export

Sulfur metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

Phenylalanine

Terpenoid backbone biosynthesis

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

O-Mannosyl glycan biosynthesis

Taurine and hypotaurine metabolism

Thiamine metabolism

Neomycin

None

Puromycin

1

Yes

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