Expression Plasmids

cDNA Clones

Expression Plasmids

Human

TCF7L2

P53

JNK2

TCF7

ACTIVIN A RECEPTOR TYPE IC

BAX

EGFR

JNK1

LEF1

MLH1

SMAD3

ACTIVIN A RECEPTOR TYPE IB

AKT1

BETA CATENIN

BIRC5

ERK1

FRIZZLED 6

JNK3

PI 3 KINASE P85 ALPHA

SMAD2

AKT3

AXIN 1

BAD

BCL2

CASPASE 3

CASPASE 9

DVL1

ERK2

GRB2

GSK3 BETA

KRAS

MET

PI 3 KINASE P55 GAMMA

PIK3R5

RAC1

RALGDS

TGF BETA 2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

A RAF

AKT2

APPL

AXIN 2

B RAF

C FOS

C-JUN

C-MYC

CYCLIN D1

CYTOCHROME C

DCC

DISHEVELLED 2

DISHEVELLED 3

FRIZZLED 10

FRIZZLED 2

FRIZZLED 4

FRIZZLED 5

FRIZZLED 7

FRIZZLED 8

FRIZZLED 9

FRIZZLED HOMOLOG 1

FZD3

IGF1 RECEPTOR

MEK1

MSH2

MSH3

MSH6

PDGF RECEPTOR ALPHA

PDGF RECEPTOR BETA

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P85 BETA

PIK3CB

PIK3CD

RAC2

RAC3

RAF1

SMAD4

SOS1

SOS2

TCF7L1

TGF BETA 1

TGF BETA 3

Plasmids

Myc-DDK

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL5-DDK-His

pCMV6-XL6

No

LentiORF

Druggable Genome

ES Cell Differentiation/IPS

Protein Kinase

Transcription Factors

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

GPCR

Adult stem cells

Embryonic stem cells

Secreted Protein

Stem cell relevant signaling - TGFb/BMP signaling pathway

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Regulation of actin cytoskeleton

Endocytosis

Focal adhesion

Chemokine signaling pathway

Calcium signaling pathway

Purine metabolism

Wnt signaling pathway

Huntington's disease

Neurotrophin signaling pathway

Alzheimer's disease

Ubiquitin mediated proteolysis

Jak-STAT signaling pathway

Axon guidance

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Cell adhesion molecules (CAMs)

Progesterone-mediated oocyte maturation

Tight junction

Cell cycle

Leukocyte transendothelial migration

Lysosome

Oocyte meiosis

T cell receptor signaling pathway

ErbB signaling pathway

Adherens junction

Fc gamma R-mediated phagocytosis

Prostate cancer

Toll-like receptor signaling pathway

Apoptosis

Hematopoietic cell lineage

Melanogenesis

Spliceosome

Vascular smooth muscle contraction

Oxidative phosphorylation

GnRH signaling pathway

Parkinson's disease

Dilated cardiomyopathy

Systemic lupus erythematosus

Colorectal cancer

Hypertrophic cardiomyopathy (HCM)

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

VEGF signaling pathway

Pyrimidine metabolism

Melanoma

B cell receptor signaling pathway

Gap junction

TGF-beta signaling pathway

PPAR signaling pathway

p53 signaling pathway

Chronic myeloid leukemia

Small cell lung cancer

Renal cell carcinoma

Antigen processing and presentation

Fc epsilon RI signaling pathway

Viral myocarditis

Acute myeloid leukemia

Complement and coagulation cascades

Glioma

RIG-I-like receptor signaling pathway

Adipocytokine signaling pathway

NOD-like receptor signaling pathway

Long-term potentiation

Phosphatidylinositol signaling system

Ribosome

Long-term depression

Epithelial cell signaling in Helicobacter pylori infection

Glycerophospholipid metabolism

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Drug metabolism - cytochrome P450

ECM-receptor interaction

Metabolism of xenobiotics by cytochrome P450

Pathogenic Escherichia coli infection

Non-small cell lung cancer

Vibrio cholerae infection

Basal cell carcinoma

mTOR signaling pathway

Bladder cancer

Cytosolic DNA-sensing pathway

Inositol phosphate metabolism

Drug metabolism - other enzymes

Retinol metabolism

Arginine and proline metabolism

Valine

Hedgehog signaling pathway

Arachidonic acid metabolism

Starch and sucrose metabolism

Glutathione metabolism

RNA degradation

Thyroid cancer

N-Glycan biosynthesis

Sphingolipid metabolism

Type II diabetes mellitus

Glycerolipid metabolism

Amino sugar and nucleotide sugar metabolism

Tyrosine metabolism

Fatty acid metabolism

leucine and isoleucine degradation

Autoimmune thyroid disease

Pyruvate metabolism

Lysine degradation

Cysteine and methionine metabolism

Primary immunodeficiency

Proteasome

Taste transduction

ABC transporters

Base excision repair

Nucleotide excision repair

Tryptophan metabolism

Type I diabetes mellitus

Notch signaling pathway

SNARE interactions in vesicular transport

Ether lipid metabolism

Alanine

aspartate and glutamate metabolism

Androgen and estrogen metabolism

Porphyrin and chlorophyll metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Prion diseases

Aminoacyl-tRNA biosynthesis

Butanoate metabolism

Glycine

serine and threonine metabolism

Citrate cycle (TCA cycle)

Allograft rejection

Glycosphingolipid biosynthesis - lacto and neolacto series

Propanoate metabolism

Basal transcription factors

DNA replication

Galactose metabolism

Pentose phosphate pathway

Selenoamino acid metabolism

Nitrogen metabolism

Histidine metabolism

Glycosaminoglycan degradation

Homologous recombination

O-Glycan biosynthesis

Regulation of autophagy

Linoleic acid metabolism

Maturity onset diabetes of the young

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Nicotinate and nicotinamide metabolism

Dorso-ventral axis formation

Mismatch repair

Phenylalanine metabolism

RNA polymerase

Asthma

Pentose and glucuronate interconversions

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Keratan sulfate biosynthesis

Ascorbate and aldarate metabolism

Pantothenate and CoA biosynthesis

One carbon pool by folate

Renin-angiotensin system

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Other glycan degradation

Sulfur metabolism

alpha-Linolenic acid metabolism

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

Glyoxylate and dicarboxylate metabolism

Glycosphingolipid biosynthesis - ganglio series

Cyanoamino acid metabolism

Limonene and pinene degradation

Taurine and hypotaurine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

Folate biosynthesis

Caffeine metabolism

Synthesis and degradation of ketone bodies

Protein export

Thiamine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Fatty acid biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

Lysine biosynthesis

D-Glutamine and D-glutamate metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

Puromycin

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