Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

14-3-3 ZETA

APC11

DP2

P16INK4A

CHK2

ORC4L

SMAD2

ARTEMIS

CDK1

CYCLIN A1

CYCLIN D3

MDM2

SMAD3

14-3-3 BETA

C ABL

CDC25B

CDC7

CDK2

CHK1

FZR1

GSK3 BETA

MAD1

P107

P19 INK4D

P21

PCNA

SA2

SKP1

TGF BETA 2

APC5

APC6

CDC14A

CDC14B

CDC25A

CDC25C

CDC27

CDC45L

CDK6

CYCLIN E1

E2F5

MCM4

MCM7

MPS1

ORC3L

ORC5L

P15 INK4B

P18 INK4C

PKMYT1

SKP2

WEE1

14 3 3 ETA

14 3 3 GAMMA

14-3-3 EPSILON

14-3-3 SIGMA

14-3-3 THETA

APC10

APC2

APC4

APC7

BUB1

BUB3

BUBR1

C-MYC

CDC20

CDC23

CDC6

CDK4

CDK7

CULLIN 1

CYCLIN A2

CYCLIN B1

CYCLIN B3

CYCLIN D1

CYCLIN D2

CYCLIN E2

DBF4

DP1

E2F1

E2F3

GADD45A

GADD45B

GADD45G

HDAC1

HDAC2

MAD2

MAD2L2

MCM2

MCM5

MCM6

MIZ1

ORC1

ORC2

P27 KIP 1

P57 KIP2

PLK1

RAD21

RB2 P130

ROC1

SECURIN

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-Myc-DDK

No

LentiORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Phosphatase

Stem cell relevant signaling - JAK/STAT signaling pathway

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Transmembrane

Stem cell relevant signaling - Wnt Signaling pathway

Adult stem cells

Induced pluripotent stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Endocytosis

Chemokine signaling pathway

Calcium signaling pathway

Wnt signaling pathway

Olfactory transduction

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Huntington's disease

Purine metabolism

Alzheimer's disease

Ubiquitin mediated proteolysis

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Axon guidance

Cell adhesion molecules (CAMs)

Leukocyte transendothelial migration

Progesterone-mediated oocyte maturation

Tight junction

T cell receptor signaling pathway

Cell cycle

Oocyte meiosis

ErbB signaling pathway

Toll-like receptor signaling pathway

Prostate cancer

Melanogenesis

Lysosome

Apoptosis

Adherens junction

GnRH signaling pathway

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

Colorectal cancer

Hematopoietic cell lineage

Pancreatic cancer

Dilated cardiomyopathy

Parkinson's disease

VEGF signaling pathway

Spliceosome

B cell receptor signaling pathway

Melanoma

Chronic myeloid leukemia

Systemic lupus erythematosus

Hypertrophic cardiomyopathy (HCM)

TGF-beta signaling pathway

Gap junction

Oxidative phosphorylation

Small cell lung cancer

Renal cell carcinoma

Fc epsilon RI signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

p53 signaling pathway

RIG-I-like receptor signaling pathway

Acute myeloid leukemia

Glioma

Adipocytokine signaling pathway

Antigen processing and presentation

NOD-like receptor signaling pathway

Long-term potentiation

PPAR signaling pathway

Pyrimidine metabolism

Viral myocarditis

Long-term depression

Complement and coagulation cascades

Epithelial cell signaling in Helicobacter pylori infection

Endometrial cancer

Amyotrophic lateral sclerosis (ALS)

Non-small cell lung cancer

Phosphatidylinositol signaling system

ECM-receptor interaction

Ribosome

mTOR signaling pathway

Glycolysis / Gluconeogenesis

Glycerophospholipid metabolism

Cardiac muscle contraction

Basal cell carcinoma

Pathogenic Escherichia coli infection

Bladder cancer

Drug metabolism - cytochrome P450

Hedgehog signaling pathway

Metabolism of xenobiotics by cytochrome P450

Vibrio cholerae infection

Cytosolic DNA-sensing pathway

Type II diabetes mellitus

Arginine and proline metabolism

Retinol metabolism

Inositol phosphate metabolism

Valine

Thyroid cancer

Drug metabolism - other enzymes

Arachidonic acid metabolism

Starch and sucrose metabolism

Autoimmune thyroid disease

Glutathione metabolism

RNA degradation

N-Glycan biosynthesis

Sphingolipid metabolism

Tyrosine metabolism

Amino sugar and nucleotide sugar metabolism

Lysine degradation

leucine and isoleucine degradation

Primary immunodeficiency

Glycerolipid metabolism

Notch signaling pathway

Pyruvate metabolism

Fatty acid metabolism

ABC transporters

Nucleotide excision repair

Type I diabetes mellitus

Tryptophan metabolism

Proteasome

Taste transduction

Cysteine and methionine metabolism

Prion diseases

Base excision repair

Graft-versus-host disease

Ether lipid metabolism

Androgen and estrogen metabolism

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Alanine

aspartate and glutamate metabolism

Citrate cycle (TCA cycle)

Allograft rejection

Regulation of autophagy

Porphyrin and chlorophyll metabolism

Propanoate metabolism

Butanoate metabolism

Glycine

serine and threonine metabolism

Maturity onset diabetes of the young

Galactose metabolism

Aminoacyl-tRNA biosynthesis

DNA replication

Glycosphingolipid biosynthesis - lacto and neolacto series

Nitrogen metabolism

Dorso-ventral axis formation

Pentose phosphate pathway

Histidine metabolism

Glycosaminoglycan degradation

Homologous recombination

Linoleic acid metabolism

O-Glycan biosynthesis

Basal transcription factors

Selenoamino acid metabolism

Asthma

Phenylalanine metabolism

Nicotinate and nicotinamide metabolism

Mismatch repair

beta-Alanine metabolism

Biosynthesis of unsaturated fatty acids

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Pentose and glucuronate interconversions

Renin-angiotensin system

Primary bile acid biosynthesis

RNA polymerase

Ascorbate and aldarate metabolism

One carbon pool by folate

Keratan sulfate biosynthesis

Riboflavin metabolism

Other glycan degradation

alpha-Linolenic acid metabolism

Non-homologous end-joining

Pantothenate and CoA biosynthesis

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Terpenoid backbone biosynthesis

Chondroitin sulfate biosynthesis

Sulfur metabolism

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

C21-Steroid hormone metabolism

leucine and isoleucine biosynthesis

Folate biosynthesis

Taurine and hypotaurine metabolism

Cyanoamino acid metabolism

Protein export

Caffeine metabolism

Thiamine metabolism

Fatty acid elongation in mitochondria

Methane metabolism

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Vitamin B6 metabolism

Lipoic acid metabolism

O-Mannosyl glycan biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Puromycin

None

1

Yes

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