Expression Plasmids

cDNA Clones

Expression Plasmids

Human

PTCH1

TCF7

LEF1

BETA CATENIN

GLI1

AXIN 1

DVL1

PTCH2

AXIN 2

BMP2

DISHEVELLED 2

DISHEVELLED 3

GLI2

GLI3

SMOOTHENED

SONIC HEDGEHOG

WNT1

WNT2

WNT3A

WNT5A

WNT6

WNT7B

WNT8A

WNT8B

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK

pLenti-C-mGFP

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

No

LentiORF

Druggable Genome

ES Cell Differentiation/IPS

Transmembrane

Transcription Factors

Secreted Protein

Adult stem cells

Cancer stem cells

GPCR

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Protein Kinase

Pathways in cancer

Cytokine-cytokine receptor interaction

Focal adhesion

MAPK signaling pathway

Wnt signaling pathway

Colorectal cancer

Hematopoietic cell lineage

Cell adhesion molecules (CAMs)

Regulation of actin cytoskeleton

Basal cell carcinoma

Jak-STAT signaling pathway

Adherens junction

Neurotrophin signaling pathway

Prostate cancer

TGF-beta signaling pathway

Pancreatic cancer

Melanoma

Endometrial cancer

ErbB signaling pathway

Hedgehog signaling pathway

Natural killer cell mediated cytotoxicity

Leukocyte transendothelial migration

Melanogenesis

Acute myeloid leukemia

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Endocytosis

Fc gamma R-mediated phagocytosis

T cell receptor signaling pathway

Glioma

Progesterone-mediated oocyte maturation

Toll-like receptor signaling pathway

Insulin signaling pathway

Maturity onset diabetes of the young

Chronic myeloid leukemia

Hypertrophic cardiomyopathy (HCM)

Fc epsilon RI signaling pathway

GnRH signaling pathway

Huntington's disease

Small cell lung cancer

ECM-receptor interaction

Adipocytokine signaling pathway

Chemokine signaling pathway

Dilated cardiomyopathy

Systemic lupus erythematosus

Tight junction

B cell receptor signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Gap junction

Metabolic pathways

Non-small cell lung cancer

Apoptosis

Renal cell carcinoma

Type II diabetes mellitus

Thyroid cancer

Axon guidance

Pathogenic Escherichia coli infection

mTOR signaling pathway

VEGF signaling pathway

Complement and coagulation cascades

Alzheimer's disease

NOD-like receptor signaling pathway

Notch signaling pathway

RIG-I-like receptor signaling pathway

Autoimmune thyroid disease

Bladder cancer

Prion diseases

p53 signaling pathway

Primary immunodeficiency

Antigen processing and presentation

Calcium signaling pathway

Cell cycle

Long-term depression

Oocyte meiosis

Amyotrophic lateral sclerosis (ALS)

Dorso-ventral axis formation

Viral myocarditis

Allograft rejection

Type I diabetes mellitus

Graft-versus-host disease

Neuroactive ligand-receptor interaction

Renin-angiotensin system

Tyrosine metabolism

Glycolysis / Gluconeogenesis

Long-term potentiation

Lysosome

Vascular smooth muscle contraction

PPAR signaling pathway

Starch and sucrose metabolism

ABC transporters

Citrate cycle (TCA cycle)

Nicotinate and nicotinamide metabolism

Parkinson's disease

Phosphatidylinositol signaling system

Pyruvate metabolism

Retinol metabolism

Vibrio cholerae infection

Amino sugar and nucleotide sugar metabolism

Asthma

Cardiac muscle contraction

Cysteine and methionine metabolism

Drug metabolism - cytochrome P450

Drug metabolism - other enzymes

Fructose and mannose metabolism

Galactose metabolism

Glutathione metabolism

Inositol phosphate metabolism

Linoleic acid metabolism

Metabolism of xenobiotics by cytochrome P450

Oxidative phosphorylation

Phenylalanine

Phenylalanine metabolism

Primary bile acid biosynthesis

Purine metabolism

Pyrimidine metabolism

Regulation of autophagy

Ubiquinone and other terpenoid-quinone biosynthesis

Ubiquitin mediated proteolysis

tyrosine and tryptophan biosynthesis

Puromycin

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