Expression Plasmids

cDNA Clones

Expression Plasmids

Human

PTCH1

WNT16

BMP2

IHH

PTCH2

SMOOTHENED

SONIC HEDGEHOG

WNT1

WNT10A

WNT11

WNT3

WNT6

WNT7A

WNT7B

WNT9A

WNT9B

WNT4

Plasmids

Myc-DDK

mGFP

pLenti-C-mGFP-P2A-Puro

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Secreted Protein

ES Cell Differentiation/IPS

Protein Kinase

Transmembrane

Cancer stem cells

Adult stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Transcription Factors

Stem cell relevant signaling - DSL/Notch pathway

Protease

Metabolic pathways

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Olfactory transduction

Cell adhesion molecules (CAMs)

Calcium signaling pathway

Pathways in cancer

Hematopoietic cell lineage

MAPK signaling pathway

Regulation of actin cytoskeleton

Natural killer cell mediated cytotoxicity

Jak-STAT signaling pathway

Alzheimer's disease

Endocytosis

Dilated cardiomyopathy

Leukocyte transendothelial migration

Chemokine signaling pathway

Axon guidance

Antigen processing and presentation

ECM-receptor interaction

Huntington's disease

Hypertrophic cardiomyopathy (HCM)

Lysosome

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Focal adhesion

N-Glycan biosynthesis

ABC transporters

Oxidative phosphorylation

Vascular smooth muscle contraction

Viral myocarditis

Melanogenesis

Parkinson's disease

Adherens junction

Colorectal cancer

Retinol metabolism

Drug metabolism - cytochrome P450

Systemic lupus erythematosus

Tight junction

Wnt signaling pathway

Apoptosis

Cardiac muscle contraction

ErbB signaling pathway

SNARE interactions in vesicular transport

Graft-versus-host disease

Neurotrophin signaling pathway

Adipocytokine signaling pathway

PPAR signaling pathway

Autoimmune thyroid disease

Basal cell carcinoma

Purine metabolism

Gap junction

Glycerophospholipid metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Metabolism of xenobiotics by cytochrome P450

Prostate cancer

Sphingolipid metabolism

Toll-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

O-Glycan biosynthesis

Allograft rejection

Vibrio cholerae infection

Melanoma

TGF-beta signaling pathway

Type I diabetes mellitus

Androgen and estrogen metabolism

Drug metabolism - other enzymes

Epithelial cell signaling in Helicobacter pylori infection

Primary immunodeficiency

Taste transduction

Starch and sucrose metabolism

T cell receptor signaling pathway

Pancreatic cancer

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Arachidonic acid metabolism

Complement and coagulation cascades

Hedgehog signaling pathway

Heparan sulfate biosynthesis

Asthma

Fc gamma R-mediated phagocytosis

Keratan sulfate biosynthesis

B cell receptor signaling pathway

Ether lipid metabolism

GnRH signaling pathway

Porphyrin and chlorophyll metabolism

Long-term depression

Fatty acid metabolism

Long-term potentiation

Glycerolipid metabolism

p53 signaling pathway

Ascorbate and aldarate metabolism

Notch signaling pathway

Renin-angiotensin system

Glycosphingolipid biosynthesis - globo series

Linoleic acid metabolism

Pentose and glucuronate interconversions

Chondroitin sulfate biosynthesis

Small cell lung cancer

Chronic myeloid leukemia

Pyrimidine metabolism

Glycosphingolipid biosynthesis - ganglio series

Tyrosine metabolism

Fc epsilon RI signaling pathway

Prion diseases

Steroid biosynthesis

Bladder cancer

Glutathione metabolism

Progesterone-mediated oocyte maturation

Biosynthesis of unsaturated fatty acids

Renal cell carcinoma

Glioma

Pathogenic Escherichia coli infection

Insulin signaling pathway

Oocyte meiosis

Non-small cell lung cancer

Riboflavin metabolism

Ubiquitin mediated proteolysis

Endometrial cancer

Nicotinate and nicotinamide metabolism

Primary bile acid biosynthesis

RIG-I-like receptor signaling pathway

Cytosolic DNA-sensing pathway

Galactose metabolism

Glycosaminoglycan degradation

Type II diabetes mellitus

Thyroid cancer

VEGF signaling pathway

alpha-Linolenic acid metabolism

Tryptophan metabolism

Phosphatidylinositol signaling system

C21-Steroid hormone metabolism

Caffeine metabolism

Cyanoamino acid metabolism

Glycolysis / Gluconeogenesis

Nitrogen metabolism

Phenylalanine metabolism

Selenoamino acid metabolism

Taurine and hypotaurine metabolism

Amino sugar and nucleotide sugar metabolism

Inositol phosphate metabolism

NOD-like receptor signaling pathway

beta-Alanine metabolism

Glycine

Limonene and pinene degradation

O-Mannosyl glycan biosynthesis

serine and threonine metabolism

Acute myeloid leukemia

Arginine and proline metabolism

Cell cycle

Dorso-ventral axis formation

Histidine metabolism

Propanoate metabolism

Valine

leucine and isoleucine degradation

Citrate cycle (TCA cycle)

Lysine degradation

Protein export

Sulfur metabolism

Base excision repair

Butanoate metabolism

Other glycan degradation

Pantothenate and CoA biosynthesis

Pyruvate metabolism

Terpenoid backbone biosynthesis

Fatty acid elongation in mitochondria

Maturity onset diabetes of the young

Ubiquinone and other terpenoid-quinone biosynthesis

Puromycin

None

1

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