Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P53

APC11

P16INK4A

P21

14-3-3 ZETA

CHK2

ARTEMIS

C ABL

GSK3 BETA

MDM2

CDK2

DP2

14-3-3 BETA

CDK1

ORC4L

SKP1

SKP2

SMAD2

TGF BETA 2

CHK1

MPS1

PCNA

CDC20

CDK4

CDK6

E2F3

P15 INK4B

PLK1

RAD21

SA2

SECURIN

14-3-3 EPSILON

14-3-3 THETA

C-MYC

CDC25A

CDC25C

CDC7

CDK7

CYCLIN D1

CYCLIN D2

CYCLIN E1

DP1

E2F1

P107

P19 INK4D

PKMYT1

SMAD3

TGF BETA 1

WEE1

14 3 3 GAMMA

14-3-3 SIGMA

ANAPC13

APC6

BUB1

BUBR1

CDC25B

CDC27

CDC45L

DBF4

FZR1

GADD45A

GADD45B

GADD45G

HDAC1

HDAC2

MAD1

MAD2

MAD2L2

MCM2

MCM4

MCM7

P18 INK4C

P27 KIP 1

ROC1

SMAD4

TGF BETA 3

14 3 3 ETA

APC2

ATR

CDC6

CULLIN 1

CYCLIN A1

CYCLIN A2

CYCLIN B1

CYCLIN E2

MCM5

MIZ1

ORC5L

P57 KIP2

RB

APC10

APC5

ATM

BUB3

CDC23

CYCLIN D3

E2F2

E2F5

EP300

KAT3A / CBP

Plasmids

Myc-DDK

Tag Free

TurboGFP

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK

pCMV6-XL5

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK-P2A-Puro

pCMV6-XL4

pCMV6-AC

pLenti-C-mGFP

pCMV6-XL6

PCMV6-Neo

No

Yes

LentiORF

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Stem cell relevant signaling - JAK/STAT signaling pathway

Secreted Protein

Phosphatase

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Cancer stem cells

Transmembrane

Stem cell relevant signaling - Wnt Signaling pathway

Induced pluripotent stem cells

Adult stem cells

Protease

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Endocytosis

Neurotrophin signaling pathway

Calcium signaling pathway

Wnt signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Insulin signaling pathway

Alzheimer's disease

Huntington's disease

Cell adhesion molecules (CAMs)

Ubiquitin mediated proteolysis

Axon guidance

T cell receptor signaling pathway

Cell cycle

Prostate cancer

Leukocyte transendothelial migration

Tight junction

Toll-like receptor signaling pathway

ErbB signaling pathway

Purine metabolism

Oocyte meiosis

Progesterone-mediated oocyte maturation

Melanogenesis

Apoptosis

Colorectal cancer

GnRH signaling pathway

Hematopoietic cell lineage

Pancreatic cancer

Fc gamma R-mediated phagocytosis

Vascular smooth muscle contraction

Olfactory transduction

Melanoma

Adherens junction

Lysosome

Chronic myeloid leukemia

Small cell lung cancer

VEGF signaling pathway

Gap junction

B cell receptor signaling pathway

Renal cell carcinoma

TGF-beta signaling pathway

Parkinson's disease

Systemic lupus erythematosus

Fc epsilon RI signaling pathway

Glioma

Spliceosome

Dilated cardiomyopathy

p53 signaling pathway

Adipocytokine signaling pathway

Acute myeloid leukemia

Antigen processing and presentation

Hypertrophic cardiomyopathy (HCM)

NOD-like receptor signaling pathway

Long-term potentiation

RIG-I-like receptor signaling pathway

Non-small cell lung cancer

Oxidative phosphorylation

Epithelial cell signaling in Helicobacter pylori infection

Endometrial cancer

Pyrimidine metabolism

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Long-term depression

ECM-receptor interaction

PPAR signaling pathway

Viral myocarditis

Complement and coagulation cascades

Bladder cancer

Amyotrophic lateral sclerosis (ALS)

mTOR signaling pathway

Ribosome

Glycolysis / Gluconeogenesis

Type II diabetes mellitus

Basal cell carcinoma

Pathogenic Escherichia coli infection

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Phosphatidylinositol signaling system

Cardiac muscle contraction

Glycerophospholipid metabolism

Vibrio cholerae infection

Metabolism of xenobiotics by cytochrome P450

Arginine and proline metabolism

Drug metabolism - cytochrome P450

Autoimmune thyroid disease

Thyroid cancer

Type I diabetes mellitus

Arachidonic acid metabolism

Retinol metabolism

Valine

Notch signaling pathway

Graft-versus-host disease

Primary immunodeficiency

Glutathione metabolism

Inositol phosphate metabolism

Pyruvate metabolism

RNA degradation

Allograft rejection

Prion diseases

Tyrosine metabolism

Proteasome

Sphingolipid metabolism

Glycerolipid metabolism

Nucleotide excision repair

Lysine degradation

leucine and isoleucine degradation

Maturity onset diabetes of the young

Taste transduction

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Fatty acid metabolism

N-Glycan biosynthesis

Tryptophan metabolism

Starch and sucrose metabolism

ABC transporters

Cysteine and methionine metabolism

Base excision repair

SNARE interactions in vesicular transport

Alanine

Fructose and mannose metabolism

aspartate and glutamate metabolism

Regulation of autophagy

Citrate cycle (TCA cycle)

Ether lipid metabolism

Androgen and estrogen metabolism

Propanoate metabolism

Dorso-ventral axis formation

DNA replication

Asthma

Butanoate metabolism

Galactose metabolism

Homologous recombination

Porphyrin and chlorophyll metabolism

Glycine

serine and threonine metabolism

Aminoacyl-tRNA biosynthesis

Pentose phosphate pathway

Glycosphingolipid biosynthesis - lacto and neolacto series

Nicotinate and nicotinamide metabolism

Linoleic acid metabolism

O-Glycan biosynthesis

Glycosaminoglycan degradation

Histidine metabolism

Nitrogen metabolism

Phenylalanine metabolism

Selenoamino acid metabolism

Mismatch repair

Basal transcription factors

beta-Alanine metabolism

Renin-angiotensin system

RNA polymerase

Heparan sulfate biosynthesis

Biosynthesis of unsaturated fatty acids

Circadian rhythm - mammal

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Other glycan degradation

Riboflavin metabolism

Non-homologous end-joining

Steroid biosynthesis

Glycosphingolipid biosynthesis - globo series

Keratan sulfate biosynthesis

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - ganglio series

One carbon pool by folate

alpha-Linolenic acid metabolism

Glyoxylate and dicarboxylate metabolism

Sulfur metabolism

Chondroitin sulfate biosynthesis

Limonene and pinene degradation

Pantothenate and CoA biosynthesis

Terpenoid backbone biosynthesis

C21-Steroid hormone metabolism

Folate biosynthesis

leucine and isoleucine biosynthesis

Taurine and hypotaurine metabolism

Cyanoamino acid metabolism

Protein export

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Methane metabolism

Thiamine metabolism

Caffeine metabolism

Fatty acid biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Phenylalanine

Vitamin B6 metabolism

tyrosine and tryptophan biosynthesis

D-Glutamine and D-glutamate metabolism

Lipoic acid metabolism

Lysine biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

D-Arginine and D-ornithine metabolism

Neomycin

None

Puromycin

1

Yes

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