Expression Plasmids

cDNA Clones

Expression Plasmids

Human

AKT1

EGFR

LEF1

HER2

KRAS

P21 RAS

P53

PI 3 KINASE P85 ALPHA

TCF7

A RAF

AKT2

AKT3

ALPHA 1 CATENIN

AXIN 2

B RAF

BAD

BETA CATENIN

C-MYC

CASPASE 9

CYCLIN D1

E CADHERIN

EGF

ERK1

ERK2

GRB2

GSK3 BETA

INTEGRIN LINKED KINASE

MEK1

MEK2

MLH1

NRAS

PDPK1

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PIK3CB

PIK3CD

PTEN

RAF1

Plasmids

mGFP

pCMV6-Entry

pCMV6-AC-GFP

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pCMV6-XL5

pLenti-C-Myc-DDK-P2A-Puro

pCMV6-XL4

pLenti-C-mGFP

pCMV6-AC

pCMV6-XL5-DDK-His

pCMV6-XL6

No

LentiORF

Druggable Genome

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Adult stem cells

Transmembrane

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Induced pluripotent stem cells

Secreted Protein

Embryonic stem cells

Stem cell relevant signaling - Wnt Signaling pathway

Phosphatase

Protease

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Pathways in cancer

Metabolic pathways

Cytokine-cytokine receptor interaction

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Neurotrophin signaling pathway

Chemokine signaling pathway

Jak-STAT signaling pathway

Natural killer cell mediated cytotoxicity

Endocytosis

Cell adhesion molecules (CAMs)

Prostate cancer

Insulin signaling pathway

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Wnt signaling pathway

Calcium signaling pathway

Chronic myeloid leukemia

Cell cycle

Colorectal cancer

Melanoma

Pancreatic cancer

Leukocyte transendothelial migration

ErbB signaling pathway

Hematopoietic cell lineage

Apoptosis

Axon guidance

Tight junction

Alzheimer's disease

Small cell lung cancer

Adipocytokine signaling pathway

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Glioma

Progesterone-mediated oocyte maturation

Melanogenesis

Renal cell carcinoma

Huntington's disease

Oocyte meiosis

TGF-beta signaling pathway

Acute myeloid leukemia

Adherens junction

Non-small cell lung cancer

Ubiquitin mediated proteolysis

Fc gamma R-mediated phagocytosis

Bladder cancer

Endometrial cancer

Gap junction

VEGF signaling pathway

Vascular smooth muscle contraction

GnRH signaling pathway

p53 signaling pathway

NOD-like receptor signaling pathway

Antigen processing and presentation

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

RIG-I-like receptor signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Long-term depression

PPAR signaling pathway

Type II diabetes mellitus

Amyotrophic lateral sclerosis (ALS)

mTOR signaling pathway

Basal cell carcinoma

Long-term potentiation

Parkinson's disease

Systemic lupus erythematosus

Hedgehog signaling pathway

Thyroid cancer

Pathogenic Escherichia coli infection

Viral myocarditis

Cytosolic DNA-sensing pathway

Lysosome

Maturity onset diabetes of the young

Glycolysis / Gluconeogenesis

Purine metabolism

Autoimmune thyroid disease

Graft-versus-host disease

Phosphatidylinositol signaling system

Allograft rejection

Type I diabetes mellitus

Complement and coagulation cascades

Metabolism of xenobiotics by cytochrome P450

Primary immunodeficiency

Spliceosome

Arginine and proline metabolism

Glycerolipid metabolism

Arachidonic acid metabolism

Glycerophospholipid metabolism

Notch signaling pathway

Nucleotide excision repair

Prion diseases

Vibrio cholerae infection

ABC transporters

Pyruvate metabolism

Retinol metabolism

Tryptophan metabolism

Drug metabolism - cytochrome P450

Lysine degradation

Sphingolipid metabolism

Citrate cycle (TCA cycle)

Proteasome

Regulation of autophagy

Base excision repair

Dorso-ventral axis formation

Oxidative phosphorylation

Tyrosine metabolism

Asthma

Cardiac muscle contraction

Homologous recombination

Inositol phosphate metabolism

Linoleic acid metabolism

Valine

Fatty acid metabolism

Glutathione metabolism

Olfactory transduction

Pyrimidine metabolism

Ribosome

Cysteine and methionine metabolism

Glycine

Mismatch repair

O-Glycan biosynthesis

RNA degradation

SNARE interactions in vesicular transport

serine and threonine metabolism

Androgen and estrogen metabolism

Butanoate metabolism

Circadian rhythm - mammal

DNA replication

Drug metabolism - other enzymes

Propanoate metabolism

leucine and isoleucine degradation

Ether lipid metabolism

Fructose and mannose metabolism

Galactose metabolism

Glycosaminoglycan degradation

Nitrogen metabolism

Starch and sucrose metabolism

Alanine

Nicotinate and nicotinamide metabolism

Non-homologous end-joining

Other glycan degradation

Phenylalanine metabolism

Renin-angiotensin system

Taste transduction

aspartate and glutamate metabolism

beta-Alanine metabolism

C21-Steroid hormone metabolism

Glycosphingolipid biosynthesis - ganglio series

Limonene and pinene degradation

Amino sugar and nucleotide sugar metabolism

Aminoacyl-tRNA biosynthesis

Methane metabolism

One carbon pool by folate

Steroid biosynthesis

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Folate biosynthesis

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Histidine metabolism

Riboflavin metabolism

alpha-Linolenic acid metabolism

Cyanoamino acid metabolism

N-Glycan biosynthesis

Pentose and glucuronate interconversions

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

Primary bile acid biosynthesis

Protein export

Synthesis and degradation of ketone bodies

leucine and isoleucine biosynthesis

D-Glutamine and D-glutamate metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Keratan sulfate biosynthesis

Pantothenate and CoA biosynthesis

Selenoamino acid metabolism

Terpenoid backbone biosynthesis

Vitamin B6 metabolism

Caffeine metabolism

Chondroitin sulfate biosynthesis

Fatty acid elongation in mitochondria

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

O-Mannosyl glycan biosynthesis

Phenylalanine

Sulfur metabolism

Taurine and hypotaurine metabolism

Thiamine metabolism

tyrosine and tryptophan biosynthesis

Puromycin

1

Yes

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