Expression Plasmids

cDNA Clones

Expression Plasmids

Human

P16INK4A

P21

P53

C ABL

CHK2

MDM2

SKP2

14-3-3 BETA

14-3-3 ZETA

C-MYC

CDC20

CDC25A

CDK2

CYCLIN D1

CYCLIN D2

E2F1

GSK3 BETA

MPS1

PCNA

PLK1

RAD21

SKP1

TGF BETA 1

TGF BETA 2

14-3-3 EPSILON

14-3-3 SIGMA

14-3-3 THETA

BUBR1

CDK1

CDK4

CDK6

CDK7

CHK1

DBF4

DP1

E2F3

GADD45A

GADD45B

GADD45G

HDAC1

HDAC2

MAD2

MCM2

P15 INK4B

P27 KIP 1

ROC1

SECURIN

SMAD2

SMAD3

SMAD4

TGF BETA 3

WEE1

14 3 3 ETA

14 3 3 GAMMA

BUB1

CDC25C

CDC6

CULLIN 1

CYCLIN A2

CYCLIN B1

CYCLIN E1

CYCLIN E2

MAD2L2

MIZ1

P107

P18 INK4C

P19 INK4D

RB

SA1

APC10

APC11

APC2

APC4

APC6

ARTEMIS

ATR

CDC23

CDC25B

CDC27

CDC7

CYCLIN A1

CYCLIN D3

DP2

E2F2

EP300

FZR1

KAT3A / CBP

MAD1

MCM4

MCM5

MCM6

MCM7

ORC2

ORC4L

ORC5L

P57 KIP2

PKMYT1

RB2 P130

SECURIN 2

SMC1L2

Plasmids

Myc-DDK

mGFP

pLenti-C-Myc-DDK

pLenti-C-mGFP-P2A-Puro

pLenti-C-Myc-DDK-P2A-Puro

pLenti-C-mGFP

No

LentiORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Secreted Protein

Stem cell relevant signaling - JAK/STAT signaling pathway

ES Cell Differentiation/IPS

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Phosphatase

Transmembrane

Cancer stem cells

Induced pluripotent stem cells

Adult stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Neurotrophin signaling pathway

Jak-STAT signaling pathway

Endocytosis

Natural killer cell mediated cytotoxicity

Wnt signaling pathway

Cell adhesion molecules (CAMs)

Insulin signaling pathway

Calcium signaling pathway

Prostate cancer

T cell receptor signaling pathway

Toll-like receptor signaling pathway

Leukocyte transendothelial migration

ErbB signaling pathway

Colorectal cancer

Cell cycle

Pancreatic cancer

Axon guidance

Tight junction

Melanoma

Chronic myeloid leukemia

Alzheimer's disease

Apoptosis

Ubiquitin mediated proteolysis

Hematopoietic cell lineage

Melanogenesis

B cell receptor signaling pathway

Progesterone-mediated oocyte maturation

Small cell lung cancer

Huntington's disease

Fc gamma R-mediated phagocytosis

Adherens junction

Fc epsilon RI signaling pathway

Oocyte meiosis

TGF-beta signaling pathway

Renal cell carcinoma

Glioma

GnRH signaling pathway

VEGF signaling pathway

Acute myeloid leukemia

Adipocytokine signaling pathway

Vascular smooth muscle contraction

Gap junction

Non-small cell lung cancer

Endometrial cancer

p53 signaling pathway

Bladder cancer

NOD-like receptor signaling pathway

RIG-I-like receptor signaling pathway

Antigen processing and presentation

Lysosome

Dilated cardiomyopathy

Hypertrophic cardiomyopathy (HCM)

Long-term potentiation

Epithelial cell signaling in Helicobacter pylori infection

Purine metabolism

Systemic lupus erythematosus

mTOR signaling pathway

Parkinson's disease

Amyotrophic lateral sclerosis (ALS)

Long-term depression

ECM-receptor interaction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

PPAR signaling pathway

Type II diabetes mellitus

Basal cell carcinoma

Viral myocarditis

Hedgehog signaling pathway

Cytosolic DNA-sensing pathway

Spliceosome

Pathogenic Escherichia coli infection

Complement and coagulation cascades

Thyroid cancer

Glycolysis / Gluconeogenesis

Autoimmune thyroid disease

Phosphatidylinositol signaling system

Maturity onset diabetes of the young

Primary immunodeficiency

Arginine and proline metabolism

Vibrio cholerae infection

Graft-versus-host disease

Notch signaling pathway

Type I diabetes mellitus

Metabolism of xenobiotics by cytochrome P450

Allograft rejection

Oxidative phosphorylation

Glycerophospholipid metabolism

Retinol metabolism

Arachidonic acid metabolism

Prion diseases

Pyruvate metabolism

Sphingolipid metabolism

Nucleotide excision repair

Pyrimidine metabolism

Regulation of autophagy

Tryptophan metabolism

Ribosome

Drug metabolism - cytochrome P450

Lysine degradation

Proteasome

Cardiac muscle contraction

Glycerolipid metabolism

Tyrosine metabolism

ABC transporters

Citrate cycle (TCA cycle)

Glutathione metabolism

Valine

Dorso-ventral axis formation

Olfactory transduction

Inositol phosphate metabolism

Base excision repair

Starch and sucrose metabolism

Cysteine and methionine metabolism

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Fructose and mannose metabolism

RNA degradation

Drug metabolism - other enzymes

Fatty acid metabolism

Propanoate metabolism

Asthma

Ether lipid metabolism

Linoleic acid metabolism

Taste transduction

Galactose metabolism

N-Glycan biosynthesis

Alanine

Homologous recombination

aspartate and glutamate metabolism

SNARE interactions in vesicular transport

Androgen and estrogen metabolism

Butanoate metabolism

Glycosaminoglycan degradation

Circadian rhythm - mammal

Glycine

serine and threonine metabolism

DNA replication

Nitrogen metabolism

O-Glycan biosynthesis

Phenylalanine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Renin-angiotensin system

Mismatch repair

Nicotinate and nicotinamide metabolism

beta-Alanine metabolism

Histidine metabolism

Other glycan degradation

Pentose phosphate pathway

Porphyrin and chlorophyll metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Limonene and pinene degradation

Heparan sulfate biosynthesis

Steroid biosynthesis

Aminoacyl-tRNA biosynthesis

Non-homologous end-joining

alpha-Linolenic acid metabolism

One carbon pool by folate

Ascorbate and aldarate metabolism

Folate biosynthesis

Riboflavin metabolism

Glyoxylate and dicarboxylate metabolism

C21-Steroid hormone metabolism

Keratan sulfate biosynthesis

Pentose and glucuronate interconversions

Methane metabolism

Primary bile acid biosynthesis

Selenoamino acid metabolism

Terpenoid backbone biosynthesis

Basal transcription factors

leucine and isoleucine biosynthesis

Pantothenate and CoA biosynthesis

Protein export

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Sulfur metabolism

Cyanoamino acid metabolism

RNA polymerase

Fatty acid elongation in mitochondria

Synthesis and degradation of ketone bodies

Chondroitin sulfate biosynthesis

Taurine and hypotaurine metabolism

Thiamine metabolism

Vitamin B6 metabolism

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid biosynthesis

Phenylalanine

tyrosine and tryptophan biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

D-Arginine and D-ornithine metabolism

O-Mannosyl glycan biosynthesis

Biotin metabolism

Lipoic acid metabolism

Lysine biosynthesis

None

Puromycin

1

Yes

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