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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

CBL

CBLB

STAT1

TPOR

TYK2

AKT1

MYC

Myc-DDK

pCMV6-Entry

Yes

TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

Transmembrane

ES Cell Differentiation/IPS

Embryonic stem cells

Induced pluripotent stem cells

Stem cell - Pluripotency

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Pathways in cancer

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

Pancreatic cancer

Mismatch repair

Prostate cancer

Melanoma

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

Thyroid cancer

Glioma

mTOR signaling pathway

Ubiquitin mediated proteolysis

p53 signaling pathway

Non-small cell lung cancer

Chronic myeloid leukemia

Focal adhesion

MAPK signaling pathway

Bladder cancer

Metabolic pathways

Type II diabetes mellitus

ErbB signaling pathway

Neurotrophin signaling pathway

Regulation of actin cytoskeleton

Endocytosis

Primary immunodeficiency

Renal cell carcinoma

Homologous recombination

Amino sugar and nucleotide sugar metabolism

Galactose metabolism

Glycolysis / Gluconeogenesis

Maturity onset diabetes of the young

Starch and sucrose metabolism

Natural killer cell mediated cytotoxicity

Dorso-ventral axis formation

Small cell lung cancer

Chemokine signaling pathway

Acute myeloid leukemia

Melanogenesis

Long-term depression

T cell receptor signaling pathway

Gap junction

VEGF signaling pathway

GnRH signaling pathway

Tight junction

Wnt signaling pathway

Apoptosis

Long-term potentiation

Progesterone-mediated oocyte maturation

Notch signaling pathway

Adherens junction

Cell cycle

Vascular smooth muscle contraction

Basal cell carcinoma

Leukocyte transendothelial migration

Phosphatidylinositol signaling system

Fc gamma R-mediated phagocytosis

Jak-STAT signaling pathway

Inositol phosphate metabolism

Calcium signaling pathway

Cytokine-cytokine receptor interaction

Amyotrophic lateral sclerosis (ALS)

Toll-like receptor signaling pathway

Huntington's disease

Adipocytokine signaling pathway

Axon guidance

Citrate cycle (TCA cycle)

Vibrio cholerae infection

Pathogenic Escherichia coli infection

Epithelial cell signaling in Helicobacter pylori infection

Dilated cardiomyopathy

Taste transduction

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Nucleotide excision repair

Prion diseases

TGF-beta signaling pathway

Oocyte meiosis

Cell adhesion molecules (CAMs)

Glutathione metabolism

Neuroactive ligand-receptor interaction

Base excision repair

Metabolism of xenobiotics by cytochrome P450

Complement and coagulation cascades

Hematopoietic cell lineage

PPAR signaling pathway

Neomycin

1

Yes

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