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Species
Target Symbol
- BRCA1 (416)
- BTK (305)
- BRCA2 (284)
- MENIN (265)
- MLH1 (261)
- GLUCOKINASE (260)
- TUBERIN (252)
- MSH2 (224)
- RET (196)
- NOTCH3 (164)
- CREM (144)
- P53 (143)
- NF2 (133)
- CACNA1G (113)
- VEGFA (112)
- FGFR1 (105)
- NRG1 (103)
- MSH6 (97)
- CACNA1C (96)
- DISC1 (96)
- BDNF (92)
- PCDH15 (89)
- PDE9A (88)
- LKB1 (87)
- TPM1 (87)
- CTNND1 (84)
- WILMS TUMOR PROTEIN (82)
- UTY (81)
- ST3GAL3 (77)
- G PROTEIN ALPHA S (75)
- KCNMA1 (75)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- EGFR (66)
- EMA (66)
- FH (66)
- FGFR2 (65)
- MORTALITY FACTOR 4 LIKE 2 (65)
- SYTL2 (65)
- TRPM3 (65)
- TCF7L2 (64)
- SYNTABULIN (62)
- E4 (61)
- HMGA1 (61)
- IKAROS (61)
- PLAGL1 (61)
- TNNT3 (61)
- ARPP21 (60)
- KCNQ2 (60)
- L2 (60)
- NDRG2 (60)
- ANKS1B (58)
- BETA CATENIN (57)
- RUNX1T1 (57)
- DYSFERLIN (54)
- DYSTROPHIN (54)
- UBE2V1 (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- KCNJ15 (53)
- ABLIM2 (52)
- FHL1 (52)
- MBD1 (52)
- MEIS2 (52)
- LDB3 (51)
- MU OPIOID RECEPTOR (51)
- PTEN (51)
- RGS3 (51)
- TPD52L2 (51)
- IKZF3 (50)
- L1 (50)
- PDLIM5 (50)
- PRKACB (50)
- BIM (49)
- BORIS (49)
- CD46 (49)
- EEF1D (49)
- FLT4 (49)
- PDE4DIP (49)
- ZNF83 (49)
- ATP2C1 (48)
- ESTROGEN RELATED RECEPTOR GAMMA (48)
- MIER1 (48)
- MYADM (48)
- SMOX (48)
- B RAF (47)
- BIN1 (47)
- DNMT3B (47)
- FGF1 (47)
- NAT1 (47)
- PARD3 (47)
- SH2B1 (47)
- TTC23 (47)
- ALPHA 1 ANTITRYPSIN (46)
- GLUCOCORTICOID RECEPTOR (46)
- GPM6B (46)
- MRPL55 (46)
- ODF2 (46)
- TNIK (46)
- CD44 (45)
- DYNC1I2 (45)
- DYSTROBREVIN ALPHA (45)
Tags
Vectors
- pCMV6-Entry (151934)
- pCMV6-AC-GFP (60634)
- pCMV6-XL5 (11545)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5165)
- pCMV6-AC (3791)
- pCMV6-XL6 (791)
- PCMV6-Neo (248)
- pCMV6-AC-Myc-DDK (151)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (49800)
- Transmembrane (29703)
- Transcription Factors (13878)
- Secreted Protein (7336)
- Protein Kinase (4870)
- Protease (2754)
- Stem cell - Pluripotency (2512)
- ES Cell Differentiation/IPS (2437)
- GPCR (1763)
- Phosphatase (1245)
- Ion Channels: Other (870)
- Nuclear Hormone Receptor (591)
- Adult stem cells (564)
- Ion Channels: Potassium (465)
- Embryonic stem cells (458)
- Cancer stem cells (291)
- Ion Channels: Cys-loop Receptors (279)
- P450 (251)
- Induced pluripotent stem cells (244)
- Ion Channels: Calcium (213)
- Ion Channels: Transient receptor potential (191)
- Stem cell relevant signaling - JAK/STAT signaling pathway (181)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (133)
- Ion Channels: Glutamate Receptors (128)
- Stem cell relevant signaling - DSL/Notch pathway (108)
- Stem cell relevant signaling - Wnt Signaling pathway (103)
- Ion Channels: Sodium (93)
- Ion Channels: ATP Receptors (66)
- Ion Channels: Cyclic nucleotide gated (41)
- Secreted (2)
Pathways
- Metabolic pathways (7068)
- Pathways in cancer (4282)
- MAPK signaling pathway (2658)
- Regulation of actin cytoskeleton (1887)
- Focal adhesion (1811)
- Cytokine-cytokine receptor interaction (1731)
- Neuroactive ligand-receptor interaction (1723)
- Insulin signaling pathway (1687)
- Endocytosis (1629)
- Colorectal cancer (1543)
- Calcium signaling pathway (1497)
- Ubiquitin mediated proteolysis (1492)
- Chemokine signaling pathway (1454)
- Neurotrophin signaling pathway (1391)
- Olfactory transduction (1336)
- Wnt signaling pathway (1292)
- Prostate cancer (1274)
- Huntington's disease (1230)
- Pancreatic cancer (1223)
- Endometrial cancer (1166)
- Tight junction (1163)
- Natural killer cell mediated cytotoxicity (1144)
- Progesterone-mediated oocyte maturation (1139)
- Alzheimer's disease (1133)
- Purine metabolism (1132)
- Jak-STAT signaling pathway (1092)
- Melanoma (1084)
- Axon guidance (1076)
- ErbB signaling pathway (1072)
- Cell cycle (1064)
- p53 signaling pathway (1032)
- B cell receptor signaling pathway (1028)
- Leukocyte transendothelial migration (1023)
- T cell receptor signaling pathway (1021)
- Vascular smooth muscle contraction (986)
- Fc epsilon RI signaling pathway (958)
- Glioma (949)
- GnRH signaling pathway (947)
- Apoptosis (932)
- Chronic myeloid leukemia (930)
- Melanogenesis (918)
- Adherens junction (914)
- Oocyte meiosis (902)
- mTOR signaling pathway (882)
- Small cell lung cancer (870)
- Cell adhesion molecules (CAMs) (864)
- Renal cell carcinoma (848)
- Non-small cell lung cancer (840)
- Fc gamma R-mediated phagocytosis (836)
- Gap junction (825)
- Dilated cardiomyopathy (823)
- Type II diabetes mellitus (820)
- Lysosome (815)
- VEGF signaling pathway (809)
- Toll-like receptor signaling pathway (779)
- Thyroid cancer (756)
- Long-term potentiation (753)
- Acute myeloid leukemia (738)
- Long-term depression (727)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (726)
- Bladder cancer (711)
- Hypertrophic cardiomyopathy (HCM) (706)
- Mismatch repair (705)
- Glycolysis / Gluconeogenesis (684)
- Spliceosome (677)
- Parkinson's disease (658)
- Hematopoietic cell lineage (656)
- Pyrimidine metabolism (647)
- Oxidative phosphorylation (642)
- Systemic lupus erythematosus (609)
- Phosphatidylinositol signaling system (602)
- Adipocytokine signaling pathway (594)
- Viral myocarditis (591)
- Amino sugar and nucleotide sugar metabolism (563)
- PPAR signaling pathway (544)
- Primary immunodeficiency (542)
- Starch and sucrose metabolism (542)
- Amyotrophic lateral sclerosis (ALS) (539)
- TGF-beta signaling pathway (533)
- ECM-receptor interaction (526)
- Antigen processing and presentation (504)
- Cardiac muscle contraction (503)
- Basal cell carcinoma (501)
- NOD-like receptor signaling pathway (496)
- Epithelial cell signaling in Helicobacter pylori infection (492)
- Ribosome (476)
- Homologous recombination (462)
- Glycerophospholipid metabolism (457)
- Inositol phosphate metabolism (452)
- RIG-I-like receptor signaling pathway (449)
- Complement and coagulation cascades (445)
- Vibrio cholerae infection (435)
- Notch signaling pathway (426)
- Pathogenic Escherichia coli infection (421)
- Galactose metabolism (419)
- Drug metabolism - cytochrome P450 (411)
- Maturity onset diabetes of the young (406)
- Metabolism of xenobiotics by cytochrome P450 (400)
- Dorso-ventral axis formation (385)
- RNA degradation (356)
- Cytosolic DNA-sensing pathway (355)
- Arginine and proline metabolism (351)
- Taste transduction (349)
- Hedgehog signaling pathway (337)
- Arachidonic acid metabolism (335)
- Glutathione metabolism (335)
- Drug metabolism - other enzymes (328)
- Retinol metabolism (321)
- Valine (318)
- Nucleotide excision repair (310)
- Tyrosine metabolism (296)
- N-Glycan biosynthesis (290)
- Pyruvate metabolism (289)
- Glycerolipid metabolism (284)
- Fatty acid metabolism (283)
- Lysine degradation (275)
- Autoimmune thyroid disease (274)
- Proteasome (272)
- Citrate cycle (TCA cycle) (271)
- leucine and isoleucine degradation (266)
- Base excision repair (262)
- Sphingolipid metabolism (262)
- ABC transporters (260)
- Prion diseases (260)
- Type I diabetes mellitus (257)
- Cysteine and methionine metabolism (242)
- Tryptophan metabolism (240)
- Graft-versus-host disease (226)
- Fructose and mannose metabolism (216)
- Porphyrin and chlorophyll metabolism (213)
- Propanoate metabolism (212)
- DNA replication (210)
- Aminoacyl-tRNA biosynthesis (209)
- SNARE interactions in vesicular transport (209)
- Glycosphingolipid biosynthesis - lacto and neolacto series (208)
- Alanine (206)
- aspartate and glutamate metabolism (206)
- Androgen and estrogen metabolism (202)
- Allograft rejection (201)
- Ether lipid metabolism (192)
- Basal transcription factors (191)
- Histidine metabolism (190)
- Selenoamino acid metabolism (181)
- Glycine (179)
- serine and threonine metabolism (179)
- Pentose phosphate pathway (178)
- Butanoate metabolism (177)
- Nitrogen metabolism (168)
- Regulation of autophagy (164)
- RNA polymerase (160)
- Phenylalanine metabolism (156)
- Glycosaminoglycan degradation (154)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (147)
- O-Glycan biosynthesis (143)
- Linoleic acid metabolism (142)
- Pentose and glucuronate interconversions (136)
- Asthma (135)
- Nicotinate and nicotinamide metabolism (135)
- Keratan sulfate biosynthesis (130)
- One carbon pool by folate (125)
- beta-Alanine metabolism (123)
- Ascorbate and aldarate metabolism (121)
- Biosynthesis of unsaturated fatty acids (120)
- Pantothenate and CoA biosynthesis (120)
- Steroid biosynthesis (117)
- Heparan sulfate biosynthesis (114)
- Riboflavin metabolism (110)
- Chondroitin sulfate biosynthesis (107)
- Primary bile acid biosynthesis (107)
- Other glycan degradation (104)
- Sulfur metabolism (97)
- alpha-Linolenic acid metabolism (96)
- Terpenoid backbone biosynthesis (94)
- Renin-angiotensin system (93)
- Glyoxylate and dicarboxylate metabolism (92)
- Non-homologous end-joining (91)
- Glycosphingolipid biosynthesis - ganglio series (88)
- Glycosphingolipid biosynthesis - globo series (88)
- Limonene and pinene degradation (86)
- Circadian rhythm - mammal (79)
- Cyanoamino acid metabolism (79)
- Taurine and hypotaurine metabolism (79)
- Protein export (77)
- leucine and isoleucine biosynthesis (76)
- Folate biosynthesis (61)
- Thiamine metabolism (60)
- C21-Steroid hormone metabolism (57)
- Caffeine metabolism (50)
- Synthesis and degradation of ketone bodies (46)
- Fatty acid elongation in mitochondria (45)
- Fatty acid biosynthesis (41)
- Methane metabolism (39)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Lipoic acid metabolism (32)
- Lysine biosynthesis (30)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- O-Mannosyl glycan biosynthesis (28)
- D-Glutamine and D-glutamate metabolism (22)
- Vitamin B6 metabolism (21)
- Biotin metabolism (20)
- D-Arginine and D-ornithine metabolism (4)
