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Species
Target Symbol
- RET (181)
- FGFR1 (66)
- UTY (47)
- EGFR (43)
- CACNA1G (42)
- FLT4 (35)
- EMA (33)
- MU OPIOID RECEPTOR (33)
- ST3GAL3 (30)
- LINGO1 (24)
- PGAP2 (24)
- CACNA1C (23)
- NRG1 (23)
- PAQR6 (22)
- TMEM218 (22)
- ZNF33A (21)
- BCL RAMBO (20)
- BDNF (20)
- MYADM (20)
- CD46 (19)
- MACROPHAGE INFLAMMATORY PROTEIN 1 BETA (19)
- MFF (19)
- SLAMF7 (19)
- ATP2C1 (18)
- ELASTIN (18)
- IFI27 (18)
- CD1E (17)
- OPALIN (17)
- ROR2 (17)
- SLC35B2 (17)
- GROWTH HORMONE RECEPTOR (16)
- SPOCK3 (16)
- VRK2 (16)
- ASPARTATE BETA HYDROXYLASE (15)
- CD63 (15)
- DYSFERLIN (15)
- KCNMA1 (15)
- METABOTROPIC GLUTAMATE RECEPTOR 4 (15)
- MTLRP (15)
- RAG1AP1 (15)
- RAGE (15)
- ACBD5 (14)
- AMYLOID PRECURSOR PROTEIN (14)
- C10ORF57 (14)
- C18ORF1 (14)
- C19ORF12 (14)
- C1ORF43 (14)
- CCDC51 (14)
- FGFR2 (14)
- GM CSF RECEPTOR ALPHA (14)
- GPR56 (14)
- GSG1 (14)
- HEME OXYGENASE 2 (14)
- HFE (14)
- KCNE1 (14)
- KCNJ15 (14)
- P2Y6 (14)
- RHD (14)
- SLC35A2 (14)
- TP53I11 (14)
- ZFYVE27 (14)
- ALPHA DYSTROGLYCAN (13)
- AMHR2 (13)
- CYBC1 (13)
- GPR161 (13)
- GRIA1 (13)
- IL31RA (13)
- KIR5.1 (13)
- LGR7 (13)
- LILRB4 (13)
- LYSMD4 (13)
- MFSD11 (13)
- OS9 (13)
- P2X2 (13)
- PCDH15 (13)
- SHISA5 (13)
- SLC44A3 (13)
- STOML1 (13)
- SURF4 (13)
- TMEM139 (13)
- TRANSMEMBRANE PROTEIN 175 (13)
- ACSL6 (12)
- ADA2 (12)
- ADAM15 (12)
- BAX (12)
- BESTROPHIN 3 (12)
- CCDC90B (12)
- CEACAM1 (12)
- CELL ADHESION MOLECULE 2 (12)
- CUX1 (12)
- DUOXA1 (12)
- EPIGEN (12)
- GDF 9 (12)
- ITGB6 (12)
- MCK10 (12)
- NADPH OXIDASE 4 (12)
- PIGG (12)
- PTGS1 (12)
- SIGLEC10 (12)
- SLC2A14 (12)
Mutants
Pathways
- Metabolic pathways (857)
- Neuroactive ligand-receptor interaction (696)
- Olfactory transduction (658)
- Cytokine-cytokine receptor interaction (568)
- Pathways in cancer (493)
- Calcium signaling pathway (415)
- Cell adhesion molecules (CAMs) (359)
- MAPK signaling pathway (341)
- Endocytosis (325)
- Hematopoietic cell lineage (222)
- Regulation of actin cytoskeleton (218)
- Thyroid cancer (192)
- Adherens junction (183)
- Alzheimer's disease (179)
- Focal adhesion (177)
- Jak-STAT signaling pathway (168)
- Axon guidance (154)
- Dilated cardiomyopathy (151)
- Prostate cancer (148)
- Vascular smooth muscle contraction (145)
- Melanoma (144)
- Natural killer cell mediated cytotoxicity (144)
- Lysosome (142)
- Hypertrophic cardiomyopathy (HCM) (129)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (126)
- ABC transporters (122)
- GnRH signaling pathway (120)
- Chemokine signaling pathway (117)
- ECM-receptor interaction (111)
- Antigen processing and presentation (110)
- N-Glycan biosynthesis (109)
- Huntington's disease (108)
- Colorectal cancer (105)
- Gap junction (104)
- ErbB signaling pathway (101)
- Oxidative phosphorylation (99)
- Drug metabolism - cytochrome P450 (98)
- Viral myocarditis (98)
- Epithelial cell signaling in Helicobacter pylori infection (97)
- Leukocyte transendothelial migration (96)
- Glycosphingolipid biosynthesis - lacto and neolacto series (95)
- Type II diabetes mellitus (94)
- Cardiac muscle contraction (93)
- Adipocytokine signaling pathway (90)
- Retinol metabolism (88)
- Metabolism of xenobiotics by cytochrome P450 (87)
- Parkinson's disease (85)
- PPAR signaling pathway (82)
- Taste transduction (81)
- SNARE interactions in vesicular transport (79)
- Purine metabolism (78)
- Systemic lupus erythematosus (78)
- Pancreatic cancer (77)
- Long-term potentiation (73)
- Long-term depression (72)
- Autoimmune thyroid disease (71)
- Drug metabolism - other enzymes (71)
- Graft-versus-host disease (70)
- Melanogenesis (70)
- Bladder cancer (68)
- Starch and sucrose metabolism (67)
- Glycerophospholipid metabolism (66)
- Porphyrin and chlorophyll metabolism (66)
- Tight junction (64)
- Arachidonic acid metabolism (63)
- Endometrial cancer (63)
- Neurotrophin signaling pathway (62)
- Keratan sulfate biosynthesis (61)
- TGF-beta signaling pathway (61)
- Type I diabetes mellitus (61)
- Allograft rejection (60)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (59)
- Non-small cell lung cancer (58)
- Amyotrophic lateral sclerosis (ALS) (57)
- Apoptosis (57)
- Sphingolipid metabolism (57)
- Androgen and estrogen metabolism (54)
- Toll-like receptor signaling pathway (54)
- Glioma (53)
- Fatty acid metabolism (52)
- O-Glycan biosynthesis (52)
- Heparan sulfate biosynthesis (49)
- Wnt signaling pathway (47)
- Dorso-ventral axis formation (46)
- Pentose and glucuronate interconversions (46)
- Notch signaling pathway (45)
- Vibrio cholerae infection (45)
- p53 signaling pathway (45)
- Primary immunodeficiency (44)
- Glutathione metabolism (43)
- Chondroitin sulfate biosynthesis (42)
- Ascorbate and aldarate metabolism (41)
- Glycosphingolipid biosynthesis - ganglio series (41)
- Basal cell carcinoma (40)
- Complement and coagulation cascades (40)
- Ether lipid metabolism (40)
- Linoleic acid metabolism (40)
- T cell receptor signaling pathway (39)
- Asthma (38)
- Prion diseases (38)
- Glycosphingolipid biosynthesis - globo series (37)
- Pyrimidine metabolism (37)
- Fc gamma R-mediated phagocytosis (35)
- Cytosolic DNA-sensing pathway (31)
- Progesterone-mediated oocyte maturation (31)
- Biosynthesis of unsaturated fatty acids (29)
- Glycerolipid metabolism (29)
- Hedgehog signaling pathway (29)
- Oocyte meiosis (29)
- Tyrosine metabolism (29)
- B cell receptor signaling pathway (28)
- Steroid biosynthesis (27)
- Fc epsilon RI signaling pathway (26)
- Riboflavin metabolism (24)
- Pathogenic Escherichia coli infection (23)
- Renal cell carcinoma (23)
- Renin-angiotensin system (21)
- Small cell lung cancer (21)
- Insulin signaling pathway (20)
- Chronic myeloid leukemia (19)
- Galactose metabolism (19)
- Glycosaminoglycan degradation (19)
- Cyanoamino acid metabolism (18)
- Selenoamino acid metabolism (18)
- Taurine and hypotaurine metabolism (18)
- alpha-Linolenic acid metabolism (18)
- Amino sugar and nucleotide sugar metabolism (15)
- Inositol phosphate metabolism (15)
- Phosphatidylinositol signaling system (15)
- Ubiquitin mediated proteolysis (15)
- Nicotinate and nicotinamide metabolism (14)
- Primary bile acid biosynthesis (13)
- Protein export (13)
- VEGF signaling pathway (13)
- Phenylalanine metabolism (11)
- RIG-I-like receptor signaling pathway (10)
- Glycine (9)
- Sulfur metabolism (9)
- beta-Alanine metabolism (9)
- serine and threonine metabolism (9)
- C21-Steroid hormone metabolism (8)
- Glycolysis / Gluconeogenesis (8)
- Nitrogen metabolism (8)
- Propanoate metabolism (8)
- Caffeine metabolism (7)
- O-Mannosyl glycan biosynthesis (7)
- Tryptophan metabolism (7)
- Valine (7)
- leucine and isoleucine degradation (7)
- Acute myeloid leukemia (6)
- Citrate cycle (TCA cycle) (6)
- Limonene and pinene degradation (5)
- Maturity onset diabetes of the young (5)
- NOD-like receptor signaling pathway (5)
- Fatty acid elongation in mitochondria (4)
- Other glycan degradation (4)
- Arginine and proline metabolism (3)
- Base excision repair (3)
- Cell cycle (3)
- Histidine metabolism (3)
- Lysine degradation (3)
- Pantothenate and CoA biosynthesis (3)
- Pyruvate metabolism (3)
- Butanoate metabolism (2)
- Terpenoid backbone biosynthesis (2)
- Ubiquinone and other terpenoid-quinone biosynthesis (2)
- Fatty acid biosynthesis (1)