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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

FGFR1

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

EGFR

PTEN

FGFR2

TCF7L2

BRAF

CTNNB1

KRAS

RAF1

BETA CATENIN

NRAS

HRAS

PIK3R5

P21 RAS

TCF7

HSP90AB1

IGF1

MDM2

HER2

IKK GAMMA

P21

AKT1

B RAF

INSULIN

LEF1

MAP2K2

PI 3 KINASE P85 ALPHA

A RAF

AKT2

AKT3

CDK2

NF-KB P65

PDPK1

PI 3 KINASE P55 GAMMA

PROSTATE SPECIFIC ANTIGEN

EGF

ERK1

GSK3 BETA

IKK BETA

ANDROGEN RECEPTOR

BCL2

CASPASE 9

CREB1

HSP90AA1

MAP2K1

MEK1

PDGF BETA

BAD

CYCLIN E1

E2F3

ERK2

GRB2

NFKB1

NKX3.1

PDGF AA

PIK3CB

SCDGFB

TGF ALPHA

IGF1 RECEPTOR

INSULIN RECEPTOR R

KAT3A / CBP

PDGF RECEPTOR ALPHA

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

RB1

E2F2

GRP94

IKK ALPHA

MEK2

P27 KIP 1

TP53

CDKN1B

CYCLIN D1

CYCLIN E2

E2F1

EP300

ERBB2

FOXO1

GST3

IKB ALPHA

KLK3

MTOR

PDGF RECEPTOR BETA

PDGFC

PI 3 KINASE P85 BETA

PIK3CD

RB

SOS1

SRD5A2

TCF7L1

GSK3B

PIK3CG

AR

ARAF

CDKN1A

CREBBP

IGF1R

MAPK1

Myc-DDK

Tag Free

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-AC-Myc-DDK

pCMV6-XL5

pCMV6-XL4

pCMV6-XL5-DDK-His

pCMV6-AC

pCMV6-XL6

PCMV6-Neo

No

Yes

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

Transmembrane

ES Cell Differentiation/IPS

Stem cell - Pluripotency

Secreted Protein

Adult stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Phosphatase

Protease

Embryonic stem cells

Induced pluripotent stem cells

Nuclear Hormone Receptor

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Insulin signaling pathway

Regulation of actin cytoskeleton

Colorectal cancer

Calcium signaling pathway

Chemokine signaling pathway

Neurotrophin signaling pathway

Prostate cancer

Pancreatic cancer

Endometrial cancer

Ubiquitin mediated proteolysis

Wnt signaling pathway

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Jak-STAT signaling pathway

Endocytosis

Melanoma

T cell receptor signaling pathway

B cell receptor signaling pathway

p53 signaling pathway

Natural killer cell mediated cytotoxicity

Cell cycle

Glioma

Fc epsilon RI signaling pathway

Apoptosis

Chronic myeloid leukemia

GnRH signaling pathway

Vascular smooth muscle contraction

Renal cell carcinoma

Non-small cell lung cancer

Axon guidance

Small cell lung cancer

Type II diabetes mellitus

Adherens junction

Melanogenesis

Gap junction

Leukocyte transendothelial migration

mTOR signaling pathway

Tight junction

Oocyte meiosis

VEGF signaling pathway

Toll-like receptor signaling pathway

Purine metabolism

Long-term potentiation

Thyroid cancer

Alzheimer's disease

Bladder cancer

Long-term depression

Acute myeloid leukemia

Dilated cardiomyopathy

Mismatch repair

Fc gamma R-mediated phagocytosis

Huntington's disease

Hematopoietic cell lineage

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

Adipocytokine signaling pathway

Hypertrophic cardiomyopathy (HCM)

Cell adhesion molecules (CAMs)

Amyotrophic lateral sclerosis (ALS)

Primary immunodeficiency

Lysosome

Olfactory transduction

TGF-beta signaling pathway

NOD-like receptor signaling pathway

Basal cell carcinoma

ECM-receptor interaction

Homologous recombination

Inositol phosphate metabolism

Starch and sucrose metabolism

Complement and coagulation cascades

Galactose metabolism

PPAR signaling pathway

Amino sugar and nucleotide sugar metabolism

Maturity onset diabetes of the young

Epithelial cell signaling in Helicobacter pylori infection

RIG-I-like receptor signaling pathway

Cardiac muscle contraction

Dorso-ventral axis formation

Notch signaling pathway

Viral myocarditis

Pathogenic Escherichia coli infection

Taste transduction

Hedgehog signaling pathway

Pyrimidine metabolism

Drug metabolism - cytochrome P450

ABC transporters

Metabolism of xenobiotics by cytochrome P450

Glycerophospholipid metabolism

Cytosolic DNA-sensing pathway

Valine

Vibrio cholerae infection

Arachidonic acid metabolism

Arginine and proline metabolism

Base excision repair

Nucleotide excision repair

Parkinson's disease

Tyrosine metabolism

Antigen processing and presentation

Glycerolipid metabolism

Retinol metabolism

Prion diseases

Drug metabolism - other enzymes

leucine and isoleucine degradation

Lysine degradation

Fatty acid metabolism

Pyruvate metabolism

Sphingolipid metabolism

Systemic lupus erythematosus

Autoimmune thyroid disease

Cysteine and methionine metabolism

Citrate cycle (TCA cycle)

Fructose and mannose metabolism

Glutathione metabolism

Tryptophan metabolism

Histidine metabolism

SNARE interactions in vesicular transport

Proteasome

Type I diabetes mellitus

Propanoate metabolism

Butanoate metabolism

Pentose phosphate pathway

Nitrogen metabolism

Alanine

aspartate and glutamate metabolism

Oxidative phosphorylation

Linoleic acid metabolism

Androgen and estrogen metabolism

Regulation of autophagy

Phenylalanine metabolism

Aminoacyl-tRNA biosynthesis

Ether lipid metabolism

Allograft rejection

DNA replication

Renin-angiotensin system

Selenoamino acid metabolism

Riboflavin metabolism

Porphyrin and chlorophyll metabolism

Spliceosome

Steroid biosynthesis

Glycosaminoglycan degradation

Non-homologous end-joining

Ribosome

beta-Alanine metabolism

Other glycan degradation

Graft-versus-host disease

Circadian rhythm - mammal

Glycine

serine and threonine metabolism

Pantothenate and CoA biosynthesis

leucine and isoleucine biosynthesis

N-Glycan biosynthesis

Primary bile acid biosynthesis

Basal transcription factors

C21-Steroid hormone metabolism

alpha-Linolenic acid metabolism

Terpenoid backbone biosynthesis

Folate biosynthesis

Asthma

Ascorbate and aldarate metabolism

Limonene and pinene degradation

One carbon pool by folate

Pentose and glucuronate interconversions

RNA degradation

Synthesis and degradation of ketone bodies

Glyoxylate and dicarboxylate metabolism

Protein export

Nicotinate and nicotinamide metabolism

Thiamine metabolism

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Biosynthesis of unsaturated fatty acids

Ubiquinone and other terpenoid-quinone biosynthesis

Taurine and hypotaurine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Sulfur metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Methane metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Biotin metabolism

RNA polymerase

O-Glycan biosynthesis

Vitamin B6 metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Neomycin

None

1

Yes

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