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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

PRKACB

TCF7L2

CTNNB1

CAMK2B

NFAT1

BETA CATENIN

CAMK2D

NFAT2

PRKCG

CAMK2G

PPP2R5C

JNK1

NFAT5

TCF7

JNK2

PPP2R1B

CYCLIN D3

NFATC4

PPAR DELTA

CASEIN KINASE 1 ALPHA

PPP3CB

TAK1

LEF1

SMAD3

PPP2R5E

CKII ALPHA

JNK3

APC

BETA TRCP

BETA TRCP2

FRA1

FRIZZLED 6

GSK3 BETA

NFAT4

PPP3CC

PRICKLE

SMAD2

CALCINEURIN A

CAMK2A

MPS1

PHOSPHOLIPASE C BETA 4

SIAH1

CK1 EPSILON

PKC BETA 1

RAC1

AXIN 1

CTNNBIP1

DVL1

NKD2

NLK

PHOSPHOLIPASE C BETA 1

PHOSPHOLIPASE C BETA 2

PP2A-BETA

PPP2R5A

PRKACA

SKP1

WNT5A

AXIN1

FZD3

KAT3A / CBP

LRP5

PHOSPHOLIPASE C BETA 3

PPP2R1A

PRESENILIN 1

AXIN 2

CALCINEURIN B

CASEIN KINASE 2 BETA

CSNK2A2

FRAT2

FRIZZLED 7

FRIZZLED 9

LRP6

MMP7

NFATC1

PKC ALPHA

PKC GAMMA

PRKACG

PRKX

RAC2

ROCK2

SENP2

TBLR1

TP53

WNT3

AXIN2

C-JUN

C-MYC

CSNK1A1L

CULLIN 1

CXXC4

CYCLIN D1

CYCLIN D2

DISHEVELLED 2

DISHEVELLED 3

DKK1

DKK2

DKK4

EP300

FRAT1

Myc-DDK

Tag Free

TurboGFP

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-XL5

pCMV6-AC-Myc-DDK

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

PCMV6-Neo

No

Yes

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Stem cell - Pluripotency

Transmembrane

Phosphatase

Secreted Protein

Stem cell relevant signaling - Wnt Signaling pathway

Cancer stem cells

Adult stem cells

GPCR

Stem cell relevant signaling - JAK/STAT signaling pathway

Embryonic stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Induced pluripotent stem cells

Nuclear Hormone Receptor

Protease

Stem cell relevant signaling - DSL/Notch pathway

Pathways in cancer

Metabolic pathways

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Focal adhesion

Insulin signaling pathway

Regulation of actin cytoskeleton

Colorectal cancer

Calcium signaling pathway

Chemokine signaling pathway

Neurotrophin signaling pathway

Prostate cancer

Pancreatic cancer

Endometrial cancer

Ubiquitin mediated proteolysis

Wnt signaling pathway

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Jak-STAT signaling pathway

Endocytosis

Melanoma

T cell receptor signaling pathway

B cell receptor signaling pathway

p53 signaling pathway

Natural killer cell mediated cytotoxicity

Cell cycle

Glioma

Fc epsilon RI signaling pathway

Apoptosis

Chronic myeloid leukemia

GnRH signaling pathway

Vascular smooth muscle contraction

Renal cell carcinoma

Non-small cell lung cancer

Axon guidance

Small cell lung cancer

Type II diabetes mellitus

Adherens junction

Melanogenesis

Gap junction

Leukocyte transendothelial migration

mTOR signaling pathway

Tight junction

Oocyte meiosis

VEGF signaling pathway

Toll-like receptor signaling pathway

Purine metabolism

Long-term potentiation

Thyroid cancer

Alzheimer's disease

Bladder cancer

Long-term depression

Acute myeloid leukemia

Dilated cardiomyopathy

Mismatch repair

Fc gamma R-mediated phagocytosis

Huntington's disease

Hematopoietic cell lineage

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

Adipocytokine signaling pathway

Hypertrophic cardiomyopathy (HCM)

Cell adhesion molecules (CAMs)

Amyotrophic lateral sclerosis (ALS)

Primary immunodeficiency

Lysosome

Olfactory transduction

TGF-beta signaling pathway

NOD-like receptor signaling pathway

Basal cell carcinoma

ECM-receptor interaction

Homologous recombination

Inositol phosphate metabolism

Starch and sucrose metabolism

Complement and coagulation cascades

Galactose metabolism

PPAR signaling pathway

Amino sugar and nucleotide sugar metabolism

Maturity onset diabetes of the young

Epithelial cell signaling in Helicobacter pylori infection

RIG-I-like receptor signaling pathway

Cardiac muscle contraction

Dorso-ventral axis formation

Notch signaling pathway

Viral myocarditis

Pathogenic Escherichia coli infection

Taste transduction

Hedgehog signaling pathway

Pyrimidine metabolism

Drug metabolism - cytochrome P450

ABC transporters

Metabolism of xenobiotics by cytochrome P450

Glycerophospholipid metabolism

Cytosolic DNA-sensing pathway

Valine

Vibrio cholerae infection

Arachidonic acid metabolism

Arginine and proline metabolism

Base excision repair

Nucleotide excision repair

Parkinson's disease

Tyrosine metabolism

Antigen processing and presentation

Glycerolipid metabolism

Retinol metabolism

Prion diseases

Drug metabolism - other enzymes

leucine and isoleucine degradation

Lysine degradation

Fatty acid metabolism

Pyruvate metabolism

Sphingolipid metabolism

Systemic lupus erythematosus

Autoimmune thyroid disease

Cysteine and methionine metabolism

Citrate cycle (TCA cycle)

Fructose and mannose metabolism

Glutathione metabolism

Tryptophan metabolism

Histidine metabolism

SNARE interactions in vesicular transport

Proteasome

Type I diabetes mellitus

Propanoate metabolism

Butanoate metabolism

Pentose phosphate pathway

Nitrogen metabolism

Alanine

aspartate and glutamate metabolism

Oxidative phosphorylation

Linoleic acid metabolism

Androgen and estrogen metabolism

Regulation of autophagy

Phenylalanine metabolism

Aminoacyl-tRNA biosynthesis

Ether lipid metabolism

Allograft rejection

DNA replication

Renin-angiotensin system

Selenoamino acid metabolism

Riboflavin metabolism

Porphyrin and chlorophyll metabolism

Spliceosome

Steroid biosynthesis

Glycosaminoglycan degradation

Non-homologous end-joining

Ribosome

beta-Alanine metabolism

Other glycan degradation

Graft-versus-host disease

Circadian rhythm - mammal

Glycine

serine and threonine metabolism

Pantothenate and CoA biosynthesis

leucine and isoleucine biosynthesis

N-Glycan biosynthesis

Primary bile acid biosynthesis

Basal transcription factors

C21-Steroid hormone metabolism

alpha-Linolenic acid metabolism

Terpenoid backbone biosynthesis

Folate biosynthesis

Asthma

Ascorbate and aldarate metabolism

Limonene and pinene degradation

One carbon pool by folate

Pentose and glucuronate interconversions

RNA degradation

Synthesis and degradation of ketone bodies

Glyoxylate and dicarboxylate metabolism

Protein export

Nicotinate and nicotinamide metabolism

Thiamine metabolism

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - ganglio series

Biosynthesis of unsaturated fatty acids

Ubiquinone and other terpenoid-quinone biosynthesis

Taurine and hypotaurine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Sulfur metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Methane metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Biotin metabolism

RNA polymerase

O-Glycan biosynthesis

Vitamin B6 metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Neomycin

None

1

Yes

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