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cDNA Clones

Expression Plasmids

Human

TCF7L2

P53

PTCH1

TCF7

LEF1

APC

BETA CATENIN

BMP4

FRIZZLED 6

GLI1

AXIN 1

DVL1

FZD3

GSK3 BETA

PTCH2

STK36

SUPPRESSOR OF FUSED

WNT5A

AXIN 2

BMP2

DISHEVELLED 2

DISHEVELLED 3

FRIZZLED 10

FRIZZLED 2

FRIZZLED 4

FRIZZLED 5

FRIZZLED 7

FRIZZLED 8

FRIZZLED 9

FRIZZLED HOMOLOG 1

GLI2

GLI3

SMOOTHENED

SONIC HEDGEHOG

TCF7L1

WNT1

WNT10B

WNT3

WNT3A

WNT4

WNT7A

TurboGFP

pCMV6-Entry

pCMV6-AC-GFP

pCMV6-AC-Myc-DDK

pCMV6-XL5

pCMV6-XL4

pCMV6-AC

pCMV6-XL6

No

TrueORF

Druggable Genome

ES Cell Differentiation/IPS

Transcription Factors

Transmembrane

Secreted Protein

Adult stem cells

Cancer stem cells

Stem cell - Pluripotency

GPCR

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Protein Kinase

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Calcium signaling pathway

Regulation of actin cytoskeleton

Focal adhesion

Chemokine signaling pathway

Jak-STAT signaling pathway

Neurotrophin signaling pathway

Wnt signaling pathway

Progesterone-mediated oocyte maturation

Insulin signaling pathway

Purine metabolism

T cell receptor signaling pathway

Apoptosis

Cell cycle

Alzheimer's disease

Natural killer cell mediated cytotoxicity

Endocytosis

ErbB signaling pathway

Axon guidance

Prostate cancer

Ubiquitin mediated proteolysis

Vascular smooth muscle contraction

GnRH signaling pathway

Oocyte meiosis

Toll-like receptor signaling pathway

Adherens junction

Leukocyte transendothelial migration

Dilated cardiomyopathy

Colorectal cancer

Hematopoietic cell lineage

Small cell lung cancer

Pancreatic cancer

Melanogenesis

Hypertrophic cardiomyopathy (HCM)

Cell adhesion molecules (CAMs)

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Renal cell carcinoma

Tight junction

VEGF signaling pathway

p53 signaling pathway

Long-term potentiation

Melanoma

Gap junction

Type II diabetes mellitus

B cell receptor signaling pathway

Chronic myeloid leukemia

Huntington's disease

Fc gamma R-mediated phagocytosis

Olfactory transduction

TGF-beta signaling pathway

Lysosome

Glioma

Acute myeloid leukemia

Adipocytokine signaling pathway

ECM-receptor interaction

NOD-like receptor signaling pathway

Endometrial cancer

Long-term depression

Fc epsilon RI signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

Complement and coagulation cascades

Non-small cell lung cancer

PPAR signaling pathway

Bladder cancer

RIG-I-like receptor signaling pathway

Cardiac muscle contraction

mTOR signaling pathway

Viral myocarditis

Basal cell carcinoma

Glycolysis / Gluconeogenesis

Epithelial cell signaling in Helicobacter pylori infection

Inositol phosphate metabolism

Hedgehog signaling pathway

Pyrimidine metabolism

Thyroid cancer

Drug metabolism - cytochrome P450

ABC transporters

Glycerophospholipid metabolism

Metabolism of xenobiotics by cytochrome P450

Taste transduction

Arachidonic acid metabolism

Pathogenic Escherichia coli infection

Antigen processing and presentation

Cytosolic DNA-sensing pathway

Glycerolipid metabolism

Base excision repair

Valine

Tyrosine metabolism

Arginine and proline metabolism

Parkinson's disease

Retinol metabolism

Drug metabolism - other enzymes

Primary immunodeficiency

Fatty acid metabolism

Lysine degradation

leucine and isoleucine degradation

Autoimmune thyroid disease

Nucleotide excision repair

Glutathione metabolism

Prion diseases

Pyruvate metabolism

Sphingolipid metabolism

Vibrio cholerae infection

Cysteine and methionine metabolism

Notch signaling pathway

Systemic lupus erythematosus

Tryptophan metabolism

Fructose and mannose metabolism

SNARE interactions in vesicular transport

Type I diabetes mellitus

Galactose metabolism

Histidine metabolism

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Homologous recombination

Butanoate metabolism

Propanoate metabolism

Proteasome

Alanine

aspartate and glutamate metabolism

Maturity onset diabetes of the young

Linoleic acid metabolism

Mismatch repair

Nitrogen metabolism

Pentose phosphate pathway

Aminoacyl-tRNA biosynthesis

Dorso-ventral axis formation

Oxidative phosphorylation

Androgen and estrogen metabolism

Ether lipid metabolism

Phenylalanine metabolism

Allograft rejection

Regulation of autophagy

Renin-angiotensin system

Citrate cycle (TCA cycle)

Selenoamino acid metabolism

DNA replication

Porphyrin and chlorophyll metabolism

Spliceosome

Graft-versus-host disease

Riboflavin metabolism

Ribosome

Glycosaminoglycan degradation

beta-Alanine metabolism

Other glycan degradation

Pantothenate and CoA biosynthesis

Non-homologous end-joining

leucine and isoleucine biosynthesis

Glycine

Steroid biosynthesis

serine and threonine metabolism

C21-Steroid hormone metabolism

Circadian rhythm - mammal

N-Glycan biosynthesis

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Terpenoid backbone biosynthesis

Asthma

Folate biosynthesis

RNA degradation

Limonene and pinene degradation

Ascorbate and aldarate metabolism

Synthesis and degradation of ketone bodies

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Pentose and glucuronate interconversions

Protein export

Fatty acid biosynthesis

Glyoxylate and dicarboxylate metabolism

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

Glycosphingolipid biosynthesis - ganglio series

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - lacto and neolacto series

Taurine and hypotaurine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Caffeine metabolism

Phenylalanine

Sulfur metabolism

tyrosine and tryptophan biosynthesis

Fatty acid elongation in mitochondria

Heparan sulfate biosynthesis

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Methane metabolism

RNA polymerase

Chondroitin sulfate biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Lysine biosynthesis

Neomycin

1

Yes

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