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Species
Target Symbol
- CD44 (12)
- FOXM1 (11)
- AKT1 (10)
- HNF 4 ALPHA (10)
- IRF5 (10)
- STAT3 (10)
- P63 (9)
- DNMT3A (8)
- GATA2 (8)
- MU OPIOID RECEPTOR (8)
- TRPA1 (8)
- AMYLOID PRECURSOR PROTEIN (7)
- BIRC5 (7)
- CREB1 (7)
- CXCR4 (7)
- DNMT1 (7)
- FGFR2 (7)
- GPBAR1 (7)
- LAMP2 (7)
- MGMT (7)
- MITF (7)
- P53 (7)
- PD-L1 (7)
- RUNX2 (7)
- SLC22A12 (7)
- SLC22A6 (7)
- SOD2 (7)
- TMEM16A (7)
- UCP2 (7)
- VEGFA (7)
- ABCG2 (6)
- ALDH1A1 (6)
- ARF1 (6)
- BACE1 (6)
- BMP7 (6)
- CD63 (6)
- CERAMIDE SYNTHASE 2 (6)
- CHRNA3 (6)
- CONSTITUTIVE ANDROSTANE RECEPTOR (6)
- CTLA4 (6)
- DDIT3 (6)
- EGFR (6)
- FOXA2 (6)
- GLUCOCORTICOID RECEPTOR (6)
- IRF1 (6)
- KLF4 (6)
- KRAS (6)
- LDHA (6)
- MCL1 (6)
- MET (6)
- NLRP3 (6)
- NOR1 (6)
- NUMB (6)
- PODXL (6)
- PPAR GAMMA (6)
- PRKACA (6)
- RAB5 (6)
- SIRT1 (6)
- SOX6 (6)
- SPHK1 (6)
- SQSTM1 (6)
- STAT1 (6)
- TLR4 (6)
- TRPV4 (6)
- VR1 (6)
- ADAM17 (5)
- ADAR1 (5)
- APE1 (5)
- APOLIPOPROTEIN L 1 (5)
- ASS1 (5)
- ATG16L1 (5)
- ATG5 (5)
- BDNF (5)
- CAMK2A (5)
- CATHEPSIN L (5)
- CD163 (5)
- DUSP6 (5)
- E2F1 (5)
- EGR1 (5)
- ELASTIN (5)
- ENDOTHELIN B RECEPTOR (5)
- ENPP1 (5)
- ERK2 (5)
- ETS1 (5)
- EZH2 (5)
- FGFR1 (5)
- FOXA1 (5)
- FOXO3 (5)
- FOXP3 (5)
- FSTL1 (5)
- FURIN (5)
- FYN (5)
- GAPDH (5)
- GATA3 (5)
- GATA4 (5)
- GATA6 (5)
- GBA (5)
- GLP1R (5)
- HER2 (5)
- HES1 (5)
Vectors
Mutants
Families
- Druggable Genome (4832)
- Transmembrane (2408)
- Transcription Factors (1313)
- Secreted Protein (698)
- ES Cell Differentiation/IPS (544)
- Protein Kinase (476)
- GPCR (273)
- Stem cell - Pluripotency (264)
- Protease (261)
- Adult stem cells (141)
- Embryonic stem cells (114)
- Nuclear Hormone Receptor (107)
- Phosphatase (90)
- Cancer stem cells (83)
- Ion Channels: Potassium (78)
- Induced pluripotent stem cells (76)
- Ion Channels: Other (72)
- P450 (47)
- Ion Channels: Transient receptor potential (43)
- Stem cell relevant signaling - DSL/Notch pathway (43)
- Stem cell relevant signaling - JAK/STAT signaling pathway (42)
- Ion Channels: Cys-loop Receptors (41)
- Stem cell relevant signaling - Wnt Signaling pathway (33)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (24)
- Ion Channels: Sodium (23)
- Ion Channels: Glutamate Receptors (19)
- Ion Channels: ATP Receptors (11)
- Ion Channels: Calcium (9)
- Ion Channels: Cyclic nucleotide gated (2)
Pathways
- Metabolic pathways (611)
- Pathways in cancer (549)
- MAPK signaling pathway (327)
- Neuroactive ligand-receptor interaction (247)
- Focal adhesion (246)
- Cytokine-cytokine receptor interaction (233)
- Regulation of actin cytoskeleton (220)
- Chemokine signaling pathway (210)
- Endocytosis (195)
- Prostate cancer (189)
- Wnt signaling pathway (181)
- Neurotrophin signaling pathway (178)
- Calcium signaling pathway (174)
- Jak-STAT signaling pathway (174)
- Insulin signaling pathway (168)
- Colorectal cancer (161)
- Alzheimer's disease (155)
- T cell receptor signaling pathway (155)
- ErbB signaling pathway (154)
- Chronic myeloid leukemia (146)
- Axon guidance (144)
- Cell cycle (144)
- Toll-like receptor signaling pathway (144)
- Huntington's disease (139)
- Melanoma (137)
- Pancreatic cancer (136)
- Melanogenesis (134)
- Apoptosis (130)
- Leukocyte transendothelial migration (129)
- Cell adhesion molecules (CAMs) (126)
- Renal cell carcinoma (126)
- Small cell lung cancer (126)
- Glioma (123)
- Adherens junction (122)
- Natural killer cell mediated cytotoxicity (122)
- Endometrial cancer (118)
- Tight junction (118)
- Acute myeloid leukemia (117)
- Fc gamma R-mediated phagocytosis (115)
- Hematopoietic cell lineage (112)
- Non-small cell lung cancer (112)
- TGF-beta signaling pathway (111)
- Progesterone-mediated oocyte maturation (107)
- VEGF signaling pathway (107)
- p53 signaling pathway (107)
- Ubiquitin mediated proteolysis (106)
- GnRH signaling pathway (105)
- Gap junction (104)
- B cell receptor signaling pathway (100)
- Lysosome (98)
- Adipocytokine signaling pathway (97)
- Bladder cancer (96)
- Vascular smooth muscle contraction (95)
- Oocyte meiosis (91)
- Fc epsilon RI signaling pathway (89)
- Purine metabolism (87)
- Basal cell carcinoma (83)
- NOD-like receptor signaling pathway (83)
- Dilated cardiomyopathy (81)
- Long-term potentiation (81)
- Parkinson's disease (78)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (77)
- Epithelial cell signaling in Helicobacter pylori infection (77)
- Hypertrophic cardiomyopathy (HCM) (77)
- Amyotrophic lateral sclerosis (ALS) (75)
- mTOR signaling pathway (75)
- RIG-I-like receptor signaling pathway (74)
- Long-term depression (72)
- Type II diabetes mellitus (72)
- Pathogenic Escherichia coli infection (70)
- Spliceosome (69)
- ECM-receptor interaction (68)
- PPAR signaling pathway (68)
- Thyroid cancer (65)
- Antigen processing and presentation (62)
- Hedgehog signaling pathway (60)
- Metabolism of xenobiotics by cytochrome P450 (60)
- Notch signaling pathway (59)
- Glycolysis / Gluconeogenesis (57)
- Cytosolic DNA-sensing pathway (55)
- Viral myocarditis (55)
- Maturity onset diabetes of the young (54)
- Drug metabolism - cytochrome P450 (52)
- Prion diseases (52)
- Systemic lupus erythematosus (52)
- Oxidative phosphorylation (50)
- Vibrio cholerae infection (49)
- Glutathione metabolism (43)
- Arachidonic acid metabolism (42)
- Cardiac muscle contraction (42)
- Dorso-ventral axis formation (41)
- Phosphatidylinositol signaling system (41)
- Retinol metabolism (41)
- Arginine and proline metabolism (40)
- Complement and coagulation cascades (40)
- Sphingolipid metabolism (39)
- Pyruvate metabolism (38)
- Type I diabetes mellitus (37)
- Citrate cycle (TCA cycle) (36)
- Cysteine and methionine metabolism (36)
- Autoimmune thyroid disease (35)
- Pyrimidine metabolism (34)
- Primary immunodeficiency (33)
- Glycerophospholipid metabolism (32)
- Inositol phosphate metabolism (32)
- Tryptophan metabolism (32)
- Allograft rejection (30)
- Androgen and estrogen metabolism (30)
- Base excision repair (30)
- Drug metabolism - other enzymes (29)
- Graft-versus-host disease (29)
- Lysine degradation (29)
- Starch and sucrose metabolism (29)
- Tyrosine metabolism (29)
- Glycerolipid metabolism (28)
- ABC transporters (27)
- Alanine (27)
- Nicotinate and nicotinamide metabolism (27)
- aspartate and glutamate metabolism (27)
- Fatty acid metabolism (26)
- Proteasome (26)
- Regulation of autophagy (26)
- DNA replication (23)
- Olfactory transduction (23)
- Valine (23)
- Fructose and mannose metabolism (21)
- Linoleic acid metabolism (21)
- N-Glycan biosynthesis (21)
- Taste transduction (21)
- Galactose metabolism (20)
- Glycine (19)
- Mismatch repair (19)
- Nitrogen metabolism (19)
- Nucleotide excision repair (19)
- Propanoate metabolism (19)
- RNA degradation (19)
- leucine and isoleucine degradation (19)
- serine and threonine metabolism (19)
- Phenylalanine metabolism (18)
- SNARE interactions in vesicular transport (18)
- Butanoate metabolism (16)
- Homologous recombination (16)
- Pentose phosphate pathway (16)
- Selenoamino acid metabolism (16)
- Amino sugar and nucleotide sugar metabolism (15)
- C21-Steroid hormone metabolism (15)
- Histidine metabolism (15)
- Porphyrin and chlorophyll metabolism (15)
- Renin-angiotensin system (15)
- Ribosome (15)
- Aminoacyl-tRNA biosynthesis (14)
- Asthma (14)
- Ether lipid metabolism (13)
- Glycosaminoglycan degradation (13)
- Steroid biosynthesis (13)
- Glycosphingolipid biosynthesis - lacto and neolacto series (11)
- Ascorbate and aldarate metabolism (10)
- Biosynthesis of unsaturated fatty acids (10)
- Glyoxylate and dicarboxylate metabolism (10)
- Limonene and pinene degradation (10)
- Pantothenate and CoA biosynthesis (10)
- beta-Alanine metabolism (10)
- Glycosphingolipid biosynthesis - globo series (9)
- O-Glycan biosynthesis (9)
- Other glycan degradation (9)
- Heparan sulfate biosynthesis (8)
- Non-homologous end-joining (8)
- Pentose and glucuronate interconversions (8)
- Riboflavin metabolism (8)
- Chondroitin sulfate biosynthesis (7)
- Circadian rhythm - mammal (7)
- Glycosphingolipid biosynthesis - ganglio series (7)
- Keratan sulfate biosynthesis (7)
- Primary bile acid biosynthesis (7)
- leucine and isoleucine biosynthesis (7)
- Folate biosynthesis (6)
- Methane metabolism (6)
- One carbon pool by folate (6)
- RNA polymerase (6)
- Sulfur metabolism (6)
- alpha-Linolenic acid metabolism (6)
- Basal transcription factors (5)
- D-Glutamine and D-glutamate metabolism (5)
- Phenylalanine (4)
- Synthesis and degradation of ketone bodies (4)
- Taurine and hypotaurine metabolism (4)
- tyrosine and tryptophan biosynthesis (4)
- Caffeine metabolism (3)
- Fatty acid elongation in mitochondria (3)
- Terpenoid backbone biosynthesis (3)
- Biotin metabolism (2)
- Cyanoamino acid metabolism (2)
- Fatty acid biosynthesis (2)
- Protein export (2)
- Thiamine metabolism (2)
- D-Arginine and D-ornithine metabolism (1)
- Lipoic acid metabolism (1)
- Lysine biosynthesis (1)
- O-Mannosyl glycan biosynthesis (1)
- Ubiquinone and other terpenoid-quinone biosynthesis (1)
- Vitamin B6 metabolism (1)
