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Species
Target Symbol
- BRCA1 (388)
- BTK (292)
- BRCA2 (273)
- GCK (249)
- TSC2 (240)
- MEN1 (237)
- MLH1 (233)
- MSH2 (212)
- RET (179)
- NOTCH3 (156)
- P53 (95)
- NF2 (87)
- MSH6 (83)
- STK11 (78)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (66)
- WT1 (62)
- FH (60)
- FGFR1 (55)
- GNAS (47)
- PTEN (43)
- EGFR (39)
- ERCC2 (37)
- BRAF (34)
- FLT4 (34)
- CTNNB1 (32)
- TERT (30)
- CBL (24)
- CDKN2A (23)
- KRAS (21)
- PRKCG (21)
- RAF1 (20)
- HRAS (18)
- NRAS (17)
- ROR2 (17)
- BETA CATENIN (14)
- ALK (13)
- MAP2K2 (12)
- GPC3 (11)
- CDKN1C (10)
- GRK1 (10)
- MYCN (10)
- AMHR2 (9)
- B RAF (9)
- BUB1B (9)
- MET (9)
- CDH1 (8)
- ACTIVIN RECEPTOR TYPE IA (7)
- CDK4 (7)
- LPAR6 (7)
- MAP2K1 (7)
- MERTK (7)
- GATA1 (6)
- P21 RAS (6)
- ZAP70 (6)
- AXIN1 (5)
- CBLB (5)
- ISOCITRATE DEHYDROGENASE (5)
- LKB1 (5)
- PAK3 (5)
- RB1 (5)
- TYK2 (5)
- DDR2 (4)
- EPHX1 (4)
- MEK1 (4)
- STAT1 (4)
- TPOR (4)
- XRCC1 (4)
- ACVR1 (3)
- AKT1 (3)
- AURKA (3)
- AXIN2 (3)
- CAMK2D (3)
- CDKN1B (3)
- GRK4 (3)
- IDH2 (3)
- LYN (3)
- MAF (3)
- MEK5 (3)
- RPS6KA3 (3)
- RSK4 (3)
- SERPIND1 (3)
- BLK (2)
- CAMK2A (2)
- CAMK2G (2)
- CAMKK2 (2)
- CASEIN KINASE 1 DELTA (2)
- CCRK (2)
- CDK2 (2)
- CDK7 (2)
- CKII ALPHA (2)
- CLK1 (2)
- CLK3 (2)
- CLK4 (2)
- DYRK2 (2)
- FGFR2 (2)
- FGFR4 (2)
- FLT3 (2)
- GRK5 (2)
- GSK3B (2)
- HER2 (2)
Brands
Families
- Druggable Genome (4118)
- Protein Kinase (1258)
- Transcription Factors (942)
- Transmembrane (426)
- Stem cell - Pluripotency (424)
- ES Cell Differentiation/IPS (141)
- Secreted Protein (93)
- Adult stem cells (46)
- Phosphatase (43)
- Stem cell relevant signaling - JAK/STAT signaling pathway (42)
- Cancer stem cells (39)
- GPCR (7)
- Stem cell relevant signaling - Wnt Signaling pathway (7)
- Induced pluripotent stem cells (5)
- Protease (4)
- Embryonic stem cells (3)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (2)
Pathways
- Pathways in cancer (1698)
- Colorectal cancer (908)
- Insulin signaling pathway (765)
- Endometrial cancer (704)
- Pancreatic cancer (629)
- Mismatch repair (528)
- Prostate cancer (525)
- Melanoma (510)
- Fc epsilon RI signaling pathway (488)
- B cell receptor signaling pathway (481)
- Glioma (469)
- Thyroid cancer (460)
- mTOR signaling pathway (457)
- MAPK signaling pathway (431)
- Non-small cell lung cancer (422)
- Ubiquitin mediated proteolysis (420)
- p53 signaling pathway (416)
- Focal adhesion (396)
- Chronic myeloid leukemia (395)
- Neurotrophin signaling pathway (370)
- ErbB signaling pathway (354)
- Bladder cancer (339)
- Regulation of actin cytoskeleton (335)
- Type II diabetes mellitus (325)
- Metabolic pathways (318)
- Endocytosis (314)
- Renal cell carcinoma (302)
- Primary immunodeficiency (299)
- Homologous recombination (273)
- Chemokine signaling pathway (252)
- Natural killer cell mediated cytotoxicity (251)
- Amino sugar and nucleotide sugar metabolism (249)
- Galactose metabolism (249)
- Glycolysis / Gluconeogenesis (249)
- Maturity onset diabetes of the young (249)
- Starch and sucrose metabolism (249)
- T cell receptor signaling pathway (245)
- Melanogenesis (239)
- Acute myeloid leukemia (235)
- Small cell lung cancer (235)
- Gap junction (230)
- Dorso-ventral axis formation (228)
- Long-term depression (225)
- GnRH signaling pathway (221)
- VEGF signaling pathway (211)
- Wnt signaling pathway (202)
- Tight junction (197)
- Long-term potentiation (196)
- Progesterone-mediated oocyte maturation (195)
- Apoptosis (180)
- Cell cycle (176)
- Vascular smooth muscle contraction (173)
- Adherens junction (172)
- Notch signaling pathway (157)
- Basal cell carcinoma (152)
- Leukocyte transendothelial migration (144)
- Fc gamma R-mediated phagocytosis (139)
- Calcium signaling pathway (135)
- Phosphatidylinositol signaling system (134)
- Toll-like receptor signaling pathway (121)
- Cytokine-cytokine receptor interaction (117)
- Jak-STAT signaling pathway (117)
- Inositol phosphate metabolism (111)
- Amyotrophic lateral sclerosis (ALS) (101)
- Adipocytokine signaling pathway (99)
- Axon guidance (99)
- Huntington's disease (95)
- Vibrio cholerae infection (74)
- Citrate cycle (TCA cycle) (68)
- Epithelial cell signaling in Helicobacter pylori infection (63)
- Pathogenic Escherichia coli infection (56)
- Dilated cardiomyopathy (51)
- Taste transduction (51)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (46)
- Oocyte meiosis (45)
- Nucleotide excision repair (39)
- TGF-beta signaling pathway (33)
- Prion diseases (30)
- Hedgehog signaling pathway (14)
- Olfactory transduction (14)
- RIG-I-like receptor signaling pathway (14)
- NOD-like receptor signaling pathway (13)
- Cell adhesion molecules (CAMs) (8)
- Glutathione metabolism (8)
- Neuroactive ligand-receptor interaction (7)
- Alzheimer's disease (6)
- Cytosolic DNA-sensing pathway (5)
- Hematopoietic cell lineage (5)
- Base excision repair (4)
- Metabolism of xenobiotics by cytochrome P450 (4)
- Regulation of autophagy (4)
- Circadian rhythm - mammal (3)
- Complement and coagulation cascades (3)
- Hypertrophic cardiomyopathy (HCM) (2)
- Viral myocarditis (2)
- PPAR signaling pathway (1)
- Parkinson's disease (1)