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Species
Target Symbol
- BRCA1 (408)
- BTK (303)
- BRCA2 (283)
- MENIN (260)
- GLUCOKINASE (256)
- MLH1 (254)
- TUBERIN (250)
- MSH2 (222)
- RET (194)
- NOTCH3 (163)
- P53 (132)
- NF2 (127)
- CREM (126)
- VEGFA (99)
- MSH6 (96)
- FGFR1 (92)
- NRG1 (89)
- CACNA1G (85)
- LKB1 (85)
- TPM1 (83)
- BDNF (79)
- DISC1 (79)
- PCDH15 (78)
- PDE9A (78)
- WILMS TUMOR PROTEIN (78)
- CACNA1C (71)
- G PROTEIN ALPHA S (70)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (70)
- FH (66)
- KCNMA1 (66)
- ST3GAL3 (64)
- CTNND1 (63)
- E4 (61)
- L2 (60)
- SYTL2 (59)
- EGFR (58)
- TCF7L2 (58)
- TNNT3 (58)
- HMGA1 (57)
- TRPM3 (57)
- BETA CATENIN (56)
- UTY (56)
- KCNQ2 (55)
- PLAGL1 (55)
- ARPP21 (53)
- FGFR2 (53)
- NDRG2 (53)
- ABLIM2 (51)
- CONSTITUTIVE ANDROSTANE RECEPTOR (51)
- FHL1 (50)
- L1 (50)
- MORTALITY FACTOR 4 LIKE 2 (50)
- PTEN (50)
- EMA (49)
- IKAROS (48)
- LDB3 (48)
- UBE2V1 (48)
- ANKS1B (47)
- B RAF (46)
- EEF1D (46)
- KCNJ15 (46)
- MEIS2 (46)
- MU OPIOID RECEPTOR (46)
- RUNX1T1 (46)
- SMOX (46)
- SYNTABULIN (46)
- GPM6B (45)
- CD46 (44)
- FLT4 (44)
- TPD52L2 (44)
- XPD (44)
- DYSFERLIN (43)
- PDE4DIP (43)
- PDLIM5 (43)
- RGS3 (43)
- CEACAM1 (42)
- GTF2IRD1 (42)
- MIER1 (42)
- ODF2 (42)
- SGK1 (42)
- SH2B1 (42)
- CD44 (41)
- DNMT3B (41)
- DYSTROPHIN (41)
- NFATC2 (41)
- PPHLN1 (41)
- PRKACB (41)
- SPHK1 (41)
- TMEM176B (41)
- TTC23 (41)
- BIN1 (40)
- IKZF3 (40)
- MBD1 (40)
- MRPL55 (40)
- PCBP2 (40)
- CELF2 (39)
- E3 (39)
- HFE (39)
- NAT1 (39)
- OXR1 (39)
Vectors
Mutants
Families
- Druggable Genome (38705)
- Transmembrane (23111)
- Transcription Factors (10787)
- Secreted Protein (5607)
- Protein Kinase (3580)
- Protease (2065)
- Stem cell - Pluripotency (2009)
- ES Cell Differentiation/IPS (1834)
- GPCR (1314)
- Phosphatase (950)
- Ion Channels: Other (671)
- Nuclear Hormone Receptor (447)
- Adult stem cells (418)
- Ion Channels: Potassium (348)
- Embryonic stem cells (339)
- Cancer stem cells (230)
- Ion Channels: Cys-loop Receptors (213)
- P450 (189)
- Induced pluripotent stem cells (178)
- Stem cell relevant signaling - JAK/STAT signaling pathway (146)
- Ion Channels: Calcium (144)
- Ion Channels: Transient receptor potential (137)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (106)
- Ion Channels: Glutamate Receptors (95)
- Stem cell relevant signaling - DSL/Notch pathway (82)
- Stem cell relevant signaling - Wnt Signaling pathway (75)
- Ion Channels: Sodium (68)
- Ion Channels: ATP Receptors (52)
- Ion Channels: Cyclic nucleotide gated (33)
Pathways
- Metabolic pathways (5563)
- Pathways in cancer (3562)
- MAPK signaling pathway (2004)
- Regulation of actin cytoskeleton (1444)
- Insulin signaling pathway (1420)
- Focal adhesion (1401)
- Colorectal cancer (1350)
- Cytokine-cytokine receptor interaction (1306)
- Neuroactive ligand-receptor interaction (1283)
- Endocytosis (1273)
- Olfactory transduction (1240)
- Ubiquitin mediated proteolysis (1213)
- Chemokine signaling pathway (1130)
- Calcium signaling pathway (1117)
- Neurotrophin signaling pathway (1067)
- Prostate cancer (1047)
- Pancreatic cancer (1039)
- Endometrial cancer (1035)
- Wnt signaling pathway (992)
- Huntington's disease (940)
- Tight junction (913)
- Natural killer cell mediated cytotoxicity (912)
- Melanoma (898)
- Purine metabolism (892)
- B cell receptor signaling pathway (880)
- Progesterone-mediated oocyte maturation (877)
- p53 signaling pathway (868)
- ErbB signaling pathway (841)
- Jak-STAT signaling pathway (835)
- Alzheimer's disease (832)
- Cell cycle (823)
- Fc epsilon RI signaling pathway (816)
- Leukocyte transendothelial migration (810)
- Axon guidance (803)
- T cell receptor signaling pathway (796)
- Glioma (790)
- Chronic myeloid leukemia (767)
- Vascular smooth muscle contraction (760)
- mTOR signaling pathway (750)
- GnRH signaling pathway (734)
- Apoptosis (727)
- Melanogenesis (724)
- Adherens junction (710)
- Non-small cell lung cancer (710)
- Small cell lung cancer (696)
- Thyroid cancer (691)
- Renal cell carcinoma (684)
- Gap junction (673)
- Type II diabetes mellitus (665)
- Oocyte meiosis (664)
- Mismatch repair (661)
- Fc gamma R-mediated phagocytosis (644)
- VEGF signaling pathway (642)
- Cell adhesion molecules (CAMs) (638)
- Dilated cardiomyopathy (633)
- Lysosome (620)
- Long-term depression (605)
- Acute myeloid leukemia (593)
- Bladder cancer (593)
- Toll-like receptor signaling pathway (593)
- Glycolysis / Gluconeogenesis (589)
- Long-term potentiation (580)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (561)
- Hypertrophic cardiomyopathy (HCM) (533)
- Spliceosome (510)
- Hematopoietic cell lineage (497)
- Pyrimidine metabolism (497)
- Phosphatidylinositol signaling system (495)
- Systemic lupus erythematosus (492)
- Amino sugar and nucleotide sugar metabolism (489)
- Parkinson's disease (484)
- Primary immunodeficiency (479)
- Starch and sucrose metabolism (476)
- Oxidative phosphorylation (475)
- Adipocytokine signaling pathway (460)
- Viral myocarditis (431)
- Amyotrophic lateral sclerosis (ALS) (420)
- Homologous recombination (420)
- PPAR signaling pathway (413)
- Basal cell carcinoma (408)
- TGF-beta signaling pathway (396)
- ECM-receptor interaction (391)
- Inositol phosphate metabolism (383)
- Cardiac muscle contraction (382)
- Galactose metabolism (382)
- Antigen processing and presentation (381)
- Epithelial cell signaling in Helicobacter pylori infection (360)
- Glycerophospholipid metabolism (360)
- Maturity onset diabetes of the young (358)
- NOD-like receptor signaling pathway (358)
- Notch signaling pathway (356)
- Vibrio cholerae infection (346)
- Complement and coagulation cascades (341)
- Dorso-ventral axis formation (341)
- Pathogenic Escherichia coli infection (341)
- RIG-I-like receptor signaling pathway (337)
- Ribosome (328)
- Drug metabolism - cytochrome P450 (323)
- Metabolism of xenobiotics by cytochrome P450 (318)
- Arginine and proline metabolism (288)
- RNA degradation (283)
- Taste transduction (282)
- Cytosolic DNA-sensing pathway (273)
- Glutathione metabolism (264)
- Arachidonic acid metabolism (257)
- Retinol metabolism (256)
- Drug metabolism - other enzymes (255)
- Valine (254)
- Nucleotide excision repair (246)
- Hedgehog signaling pathway (234)
- Citrate cycle (TCA cycle) (230)
- Tyrosine metabolism (230)
- N-Glycan biosynthesis (228)
- Fatty acid metabolism (224)
- Pyruvate metabolism (222)
- leucine and isoleucine degradation (216)
- Glycerolipid metabolism (215)
- Lysine degradation (209)
- Proteasome (207)
- Base excision repair (206)
- ABC transporters (204)
- Autoimmune thyroid disease (202)
- Sphingolipid metabolism (199)
- Prion diseases (195)
- Cysteine and methionine metabolism (187)
- Tryptophan metabolism (181)
- Type I diabetes mellitus (181)
- Porphyrin and chlorophyll metabolism (168)
- Fructose and mannose metabolism (165)
- DNA replication (162)
- Alanine (161)
- Propanoate metabolism (161)
- aspartate and glutamate metabolism (161)
- Glycosphingolipid biosynthesis - lacto and neolacto series (160)
- Aminoacyl-tRNA biosynthesis (159)
- Graft-versus-host disease (157)
- SNARE interactions in vesicular transport (155)
- Androgen and estrogen metabolism (153)
- Ether lipid metabolism (149)
- Histidine metabolism (149)
- Basal transcription factors (146)
- Selenoamino acid metabolism (144)
- Pentose phosphate pathway (142)
- Butanoate metabolism (141)
- Allograft rejection (140)
- Glycine (140)
- serine and threonine metabolism (140)
- Nitrogen metabolism (136)
- RNA polymerase (126)
- Regulation of autophagy (124)
- Glycosaminoglycan degradation (120)
- Phenylalanine metabolism (119)
- Linoleic acid metabolism (113)
- Pentose and glucuronate interconversions (112)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (109)
- O-Glycan biosynthesis (108)
- Nicotinate and nicotinamide metabolism (104)
- Pantothenate and CoA biosynthesis (101)
- Keratan sulfate biosynthesis (100)
- One carbon pool by folate (98)
- beta-Alanine metabolism (95)
- Ascorbate and aldarate metabolism (94)
- Steroid biosynthesis (94)
- Asthma (91)
- Heparan sulfate biosynthesis (91)
- Biosynthesis of unsaturated fatty acids (90)
- Chondroitin sulfate biosynthesis (82)
- Primary bile acid biosynthesis (82)
- Riboflavin metabolism (82)
- Other glycan degradation (80)
- Sulfur metabolism (78)
- alpha-Linolenic acid metabolism (75)
- Terpenoid backbone biosynthesis (72)
- Glycosphingolipid biosynthesis - ganglio series (71)
- Non-homologous end-joining (71)
- Glyoxylate and dicarboxylate metabolism (70)
- Glycosphingolipid biosynthesis - globo series (68)
- Renin-angiotensin system (68)
- Circadian rhythm - mammal (65)
- Limonene and pinene degradation (65)
- Cyanoamino acid metabolism (61)
- Taurine and hypotaurine metabolism (61)
- leucine and isoleucine biosynthesis (60)
- Protein export (53)
- Folate biosynthesis (47)
- Thiamine metabolism (44)
- C21-Steroid hormone metabolism (43)
- Fatty acid elongation in mitochondria (38)
- Caffeine metabolism (36)
- Synthesis and degradation of ketone bodies (36)
- Fatty acid biosynthesis (31)
- Methane metabolism (28)
- Ubiquinone and other terpenoid-quinone biosynthesis (28)
- Lipoic acid metabolism (27)
- Lysine biosynthesis (27)
- O-Mannosyl glycan biosynthesis (22)
- Phenylalanine (21)
- tyrosine and tryptophan biosynthesis (21)
- D-Glutamine and D-glutamate metabolism (18)
- Biotin metabolism (16)
- Vitamin B6 metabolism (15)
- D-Arginine and D-ornithine metabolism (3)
