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Species
Target Symbol
- BDNF (16)
- CONSTITUTIVE ANDROSTANE RECEPTOR (13)
- PDE9A (11)
- ALPHA 1 ANTITRYPSIN (10)
- BIN1 (8)
- CD59 (8)
- CHRM2 (8)
- NAT1 (8)
- NCALD (8)
- NDRG2 (8)
- ABLIM2 (7)
- APC11 (7)
- BANP (7)
- CACNB2 (7)
- GABA A RECEPTOR ALPHA 1 (7)
- HMGA1 (7)
- NRG1 (7)
- PPP2R2B (7)
- RIBONUCLEASE INHIBITOR (7)
- TCF7L2 (7)
- TTC23 (7)
- UBE2D3 (7)
- ZFYVE27 (7)
- ALKALINE PHOSPHATASE (6)
- APOL3 (6)
- APRATAXIN (6)
- ARCHAEMETZINCIN 2 (6)
- AURORA A (6)
- CABYR (6)
- CAMK2B (6)
- DISC1 (6)
- DYSTROBREVIN ALPHA (6)
- FHL1 (6)
- HNRNP F (6)
- IL32 (6)
- IRF5 (6)
- MBNL1 (6)
- MTH1 (6)
- MU OPIOID RECEPTOR (6)
- NEK6 (6)
- OSBPL9 (6)
- PQBP1 (6)
- PRKAR1B (6)
- RBFOX1 (6)
- RNASE9 (6)
- SSH3BP1 (6)
- STEROL CARRIER PROTEIN 2 (6)
- TPM1 (6)
- TSPAN4 (6)
- ZBTB20 (6)
- 14-3-3 ZETA (5)
- ACRV1 (5)
- B3GALT5 (5)
- CAMKK2 (5)
- CATHEPSIN B (5)
- CD1E (5)
- CD32B (5)
- CERKL (5)
- CHID1 (5)
- CLAUDIN 14 (5)
- CLDND1 (5)
- CREM (5)
- CRISP2 (5)
- CUG BP1 (5)
- DGLUCY (5)
- DYSTROPHIN (5)
- EEF1D (5)
- ER81 (5)
- FGFR1 (5)
- FXYD6 (5)
- GABPB2 (5)
- GCNT1 (5)
- GM CSF RECEPTOR ALPHA (5)
- HNRNP Q (5)
- IMPDH1 (5)
- KCNMB3 (5)
- MEIS2 (5)
- MGAT1 (5)
- MSF (5)
- MYOSIN (5)
- NFYC (5)
- OPA1 (5)
- P2X2 (5)
- P38 (5)
- P63 (5)
- PAX2 (5)
- PCBP2 (5)
- PPHLN1 (5)
- PRAME (5)
- RAD17 (5)
- RASGRP 4 (5)
- S100 CALCIUM BINDING PROTEIN A13 (5)
- SEPTIN4 (5)
- SHUGOSHIN (5)
- SNRPN (5)
- SULT1A1 (5)
- TGIF (5)
- THYN1 (5)
- TRKB (5)
- WDR21A (5)
Tags
Mutants
Families
- Druggable Genome (7446)
- Transmembrane (4411)
- Transcription Factors (1887)
- Secreted Protein (1352)
- Protein Kinase (577)
- Protease (485)
- ES Cell Differentiation/IPS (423)
- Stem cell - Pluripotency (383)
- GPCR (275)
- Phosphatase (205)
- Ion Channels: Other (157)
- Adult stem cells (113)
- Embryonic stem cells (94)
- Nuclear Hormone Receptor (84)
- Ion Channels: Potassium (76)
- Induced pluripotent stem cells (55)
- Cancer stem cells (54)
- P450 (50)
- Ion Channels: Cys-loop Receptors (40)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (31)
- Stem cell relevant signaling - JAK/STAT signaling pathway (30)
- Stem cell relevant signaling - Wnt Signaling pathway (25)
- Ion Channels: Transient receptor potential (19)
- Stem cell relevant signaling - DSL/Notch pathway (15)
- Ion Channels: Glutamate Receptors (13)
- Ion Channels: ATP Receptors (11)
- Ion Channels: Sodium (7)
- Ion Channels: Cyclic nucleotide gated (5)
- Ion Channels: Calcium (3)
Pathways
- Metabolic pathways (1245)
- Pathways in cancer (432)
- MAPK signaling pathway (357)
- Cytokine-cytokine receptor interaction (284)
- Regulation of actin cytoskeleton (256)
- Neuroactive ligand-receptor interaction (254)
- Focal adhesion (220)
- Endocytosis (219)
- Chemokine signaling pathway (215)
- Neurotrophin signaling pathway (196)
- Wnt signaling pathway (196)
- Purine metabolism (193)
- Huntington's disease (188)
- Calcium signaling pathway (180)
- Alzheimer's disease (172)
- Ubiquitin mediated proteolysis (170)
- Jak-STAT signaling pathway (166)
- Insulin signaling pathway (161)
- Cell cycle (160)
- Oocyte meiosis (154)
- Tight junction (149)
- Leukocyte transendothelial migration (146)
- Axon guidance (145)
- Lysosome (143)
- Natural killer cell mediated cytotoxicity (143)
- Olfactory transduction (143)
- Progesterone-mediated oocyte maturation (140)
- T cell receptor signaling pathway (134)
- Spliceosome (133)
- Systemic lupus erythematosus (132)
- Cell adhesion molecules (CAMs) (131)
- Hematopoietic cell lineage (123)
- ErbB signaling pathway (122)
- Melanogenesis (122)
- Apoptosis (120)
- Oxidative phosphorylation (119)
- Toll-like receptor signaling pathway (119)
- Parkinson's disease (118)
- Prostate cancer (117)
- Fc gamma R-mediated phagocytosis (116)
- GnRH signaling pathway (116)
- Antigen processing and presentation (115)
- Vascular smooth muscle contraction (115)
- Dilated cardiomyopathy (112)
- Hypertrophic cardiomyopathy (HCM) (109)
- Pyrimidine metabolism (109)
- Colorectal cancer (106)
- Adherens junction (104)
- Small cell lung cancer (103)
- TGF-beta signaling pathway (103)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (97)
- Pancreatic cancer (97)
- B cell receptor signaling pathway (95)
- Ribosome (95)
- Chronic myeloid leukemia (94)
- Gap junction (94)
- Melanoma (94)
- VEGF signaling pathway (92)
- Complement and coagulation cascades (91)
- PPAR signaling pathway (91)
- Fc epsilon RI signaling pathway (90)
- p53 signaling pathway (90)
- Adipocytokine signaling pathway (89)
- Renal cell carcinoma (88)
- Glycolysis / Gluconeogenesis (87)
- Glioma (85)
- Cardiac muscle contraction (84)
- Acute myeloid leukemia (83)
- Long-term potentiation (79)
- NOD-like receptor signaling pathway (79)
- Pathogenic Escherichia coli infection (79)
- Epithelial cell signaling in Helicobacter pylori infection (78)
- Phosphatidylinositol signaling system (78)
- Long-term depression (77)
- RIG-I-like receptor signaling pathway (77)
- Glycerophospholipid metabolism (76)
- Metabolism of xenobiotics by cytochrome P450 (74)
- Drug metabolism - cytochrome P450 (73)
- Viral myocarditis (73)
- Endometrial cancer (72)
- Non-small cell lung cancer (72)
- ECM-receptor interaction (71)
- Valine (68)
- Arginine and proline metabolism (67)
- Vibrio cholerae infection (67)
- Amyotrophic lateral sclerosis (ALS) (63)
- Basal cell carcinoma (63)
- Hedgehog signaling pathway (63)
- Cytosolic DNA-sensing pathway (62)
- RNA degradation (60)
- mTOR signaling pathway (60)
- Drug metabolism - other enzymes (58)
- leucine and isoleucine degradation (57)
- Amino sugar and nucleotide sugar metabolism (56)
- Glutathione metabolism (56)
- Inositol phosphate metabolism (56)
- Thyroid cancer (56)
- Proteasome (55)
- Arachidonic acid metabolism (54)
- Retinol metabolism (54)
- Autoimmune thyroid disease (52)
- Pyruvate metabolism (52)
- Fatty acid metabolism (51)
- Nucleotide excision repair (51)
- Starch and sucrose metabolism (50)
- Bladder cancer (48)
- Glycerolipid metabolism (48)
- Tyrosine metabolism (47)
- Type II diabetes mellitus (46)
- Notch signaling pathway (45)
- Tryptophan metabolism (45)
- Alanine (44)
- Fructose and mannose metabolism (44)
- Graft-versus-host disease (44)
- Primary immunodeficiency (44)
- Taste transduction (44)
- Type I diabetes mellitus (44)
- aspartate and glutamate metabolism (44)
- N-Glycan biosynthesis (43)
- Sphingolipid metabolism (43)
- Base excision repair (42)
- SNARE interactions in vesicular transport (42)
- Cysteine and methionine metabolism (41)
- Butanoate metabolism (40)
- Glycosphingolipid biosynthesis - lacto and neolacto series (39)
- Lysine degradation (39)
- Propanoate metabolism (39)
- Aminoacyl-tRNA biosynthesis (38)
- Androgen and estrogen metabolism (38)
- DNA replication (38)
- Pentose phosphate pathway (38)
- Porphyrin and chlorophyll metabolism (38)
- Allograft rejection (37)
- Citrate cycle (TCA cycle) (37)
- Ether lipid metabolism (37)
- Prion diseases (37)
- Regulation of autophagy (37)
- Galactose metabolism (34)
- Histidine metabolism (34)
- Glycine (33)
- O-Glycan biosynthesis (33)
- Selenoamino acid metabolism (33)
- serine and threonine metabolism (33)
- Basal transcription factors (31)
- Linoleic acid metabolism (31)
- Nitrogen metabolism (31)
- Asthma (29)
- Maturity onset diabetes of the young (29)
- Glycosaminoglycan degradation (28)
- Homologous recombination (28)
- RNA polymerase (28)
- Dorso-ventral axis formation (27)
- beta-Alanine metabolism (27)
- Nicotinate and nicotinamide metabolism (26)
- Sulfur metabolism (26)
- Mismatch repair (25)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (24)
- Heparan sulfate biosynthesis (24)
- Primary bile acid biosynthesis (24)
- Biosynthesis of unsaturated fatty acids (23)
- Phenylalanine metabolism (23)
- Pantothenate and CoA biosynthesis (21)
- Pentose and glucuronate interconversions (21)
- Riboflavin metabolism (21)
- Keratan sulfate biosynthesis (20)
- Terpenoid backbone biosynthesis (20)
- alpha-Linolenic acid metabolism (20)
- Chondroitin sulfate biosynthesis (19)
- Glycosphingolipid biosynthesis - globo series (19)
- One carbon pool by folate (19)
- Other glycan degradation (19)
- Ascorbate and aldarate metabolism (18)
- Glyoxylate and dicarboxylate metabolism (18)
- Renin-angiotensin system (17)
- C21-Steroid hormone metabolism (16)
- Glycosphingolipid biosynthesis - ganglio series (16)
- Steroid biosynthesis (16)
- leucine and isoleucine biosynthesis (16)
- ABC transporters (15)
- Non-homologous end-joining (15)
- Folate biosynthesis (14)
- Limonene and pinene degradation (14)
- Taurine and hypotaurine metabolism (14)
- Caffeine metabolism (13)
- Circadian rhythm - mammal (13)
- Thiamine metabolism (12)
- Cyanoamino acid metabolism (11)
- Fatty acid elongation in mitochondria (11)
- Protein export (9)
- Synthesis and degradation of ketone bodies (9)
- Ubiquinone and other terpenoid-quinone biosynthesis (9)
- Methane metabolism (7)
- Fatty acid biosynthesis (6)
- Lipoic acid metabolism (6)
- D-Glutamine and D-glutamate metabolism (4)
- Lysine biosynthesis (4)
- Phenylalanine (4)
- Vitamin B6 metabolism (4)
- tyrosine and tryptophan biosynthesis (4)
- O-Mannosyl glycan biosynthesis (3)
- Biotin metabolism (2)
- D-Arginine and D-ornithine metabolism (1)
