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Species
Target Symbol
- RET (182)
- FGFR1 (73)
- CACNA1G (56)
- UTY (50)
- EGFR (49)
- CACNA1C (46)
- FLT4 (38)
- EMA (36)
- ST3GAL3 (32)
- NRG1 (29)
- DYSFERLIN (28)
- ALPHA DYSTROGLYCAN (26)
- MU OPIOID RECEPTOR (26)
- GROWTH HORMONE RECEPTOR (24)
- CD46 (23)
- PCDH15 (23)
- ATP2C1 (22)
- PAQR6 (22)
- BCL RAMBO (21)
- CD1E (21)
- TMEM218 (21)
- ASPARTATE BETA HYDROXYLASE (20)
- FGFR2 (20)
- PGAP2 (19)
- BDNF (18)
- CD299 (18)
- ELASTIN (18)
- ROR2 (18)
- ADAM15 (17)
- C10ORF57 (17)
- CADHERIN LIKE 23 (17)
- KCNMA1 (17)
- MYELIN OLIGODENDROCYTE GLYCOPROTEIN (17)
- SPOCK3 (17)
- TRPM3 (17)
- AMYLOID PRECURSOR PROTEIN (16)
- ANK1 (16)
- GPR56 (16)
- GPR64 (16)
- HFE (16)
- KCNJ15 (16)
- PTGER3 (16)
- RAGE (16)
- CD63 (15)
- CD89 (15)
- CMTM1 (15)
- KCNE1 (15)
- MCK10 (15)
- MET (15)
- MFF (15)
- SLITRK2 (15)
- C18ORF1 (14)
- CELL ADHESION MOLECULE 2 (14)
- METABOTROPIC GLUTAMATE RECEPTOR 4 (14)
- MFSD11 (14)
- MTLRP (14)
- OS9 (14)
- PTCH1 (14)
- TOR2A (14)
- AMHR2 (13)
- CCDC51 (13)
- CCK4 (13)
- CD133 (13)
- CD44 (13)
- CTAGE5 (13)
- CUX1 (13)
- GM CSF RECEPTOR ALPHA (13)
- MYADM (13)
- PCDH11X (13)
- RTN3 (13)
- SERCA3 (13)
- SHISA5 (13)
- SLC44A3 (13)
- STOML1 (13)
- STRA6 (13)
- TLCD5 (13)
- TMEM139 (13)
- ZNF33A (13)
- ABCG1 (12)
- ASTN2 (12)
- CD39 (12)
- CPT1B (12)
- DMT1 (12)
- DUOXA1 (12)
- FXYD3 (12)
- GPR161 (12)
- GRIA1 (12)
- HHAT (12)
- LGR7 (12)
- LINGO1 (12)
- NAV1.5 (12)
- OPALIN (12)
- PRION PROTEIN PRP (12)
- PTPRD (12)
- RAG1AP1 (12)
- SEMA6D (12)
- SLC16A3 (12)
- STEAP2 (12)
- SVH (12)
- TP53I11 (12)
Mutants
Pathways
- Metabolic pathways (867)
- Neuroactive ligand-receptor interaction (747)
- Cytokine-cytokine receptor interaction (609)
- Olfactory transduction (582)
- Pathways in cancer (545)
- Calcium signaling pathway (504)
- MAPK signaling pathway (410)
- Cell adhesion molecules (CAMs) (398)
- Endocytosis (367)
- Regulation of actin cytoskeleton (248)
- Hematopoietic cell lineage (240)
- Alzheimer's disease (225)
- Adherens junction (210)
- Focal adhesion (201)
- Dilated cardiomyopathy (196)
- Thyroid cancer (196)
- Jak-STAT signaling pathway (178)
- Hypertrophic cardiomyopathy (HCM) (174)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (172)
- Vascular smooth muscle contraction (172)
- Prostate cancer (171)
- Axon guidance (169)
- Melanoma (169)
- Natural killer cell mediated cytotoxicity (158)
- GnRH signaling pathway (147)
- ABC transporters (146)
- Lysosome (146)
- Type II diabetes mellitus (143)
- Cardiac muscle contraction (128)
- ECM-receptor interaction (128)
- Colorectal cancer (126)
- ErbB signaling pathway (120)
- Gap junction (116)
- Epithelial cell signaling in Helicobacter pylori infection (114)
- Viral myocarditis (114)
- N-Glycan biosynthesis (113)
- Oxidative phosphorylation (113)
- Huntington's disease (112)
- Chemokine signaling pathway (109)
- Antigen processing and presentation (107)
- Drug metabolism - cytochrome P450 (98)
- Leukocyte transendothelial migration (98)
- Long-term potentiation (98)
- Parkinson's disease (94)
- Retinol metabolism (88)
- Adipocytokine signaling pathway (87)
- Glycosphingolipid biosynthesis - lacto and neolacto series (87)
- Systemic lupus erythematosus (87)
- Pancreatic cancer (86)
- Metabolism of xenobiotics by cytochrome P450 (85)
- PPAR signaling pathway (81)
- Bladder cancer (80)
- Autoimmune thyroid disease (79)
- Purine metabolism (79)
- Taste transduction (79)
- SNARE interactions in vesicular transport (78)
- Graft-versus-host disease (75)
- Melanogenesis (75)
- Endometrial cancer (71)
- Long-term depression (70)
- Starch and sucrose metabolism (68)
- Type I diabetes mellitus (66)
- Drug metabolism - other enzymes (65)
- Tight junction (65)
- Glycerophospholipid metabolism (64)
- Non-small cell lung cancer (64)
- Amyotrophic lateral sclerosis (ALS) (63)
- Apoptosis (63)
- Glioma (63)
- Keratan sulfate biosynthesis (63)
- Allograft rejection (62)
- Neurotrophin signaling pathway (62)
- TGF-beta signaling pathway (62)
- Toll-like receptor signaling pathway (62)
- Arachidonic acid metabolism (61)
- Porphyrin and chlorophyll metabolism (60)
- Androgen and estrogen metabolism (59)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (58)
- Sphingolipid metabolism (57)
- Dorso-ventral axis formation (53)
- Wnt signaling pathway (53)
- Basal cell carcinoma (52)
- Notch signaling pathway (51)
- O-Glycan biosynthesis (51)
- Vibrio cholerae infection (51)
- Fatty acid metabolism (50)
- Complement and coagulation cascades (49)
- T cell receptor signaling pathway (47)
- Primary immunodeficiency (46)
- Pentose and glucuronate interconversions (45)
- Fc gamma R-mediated phagocytosis (44)
- Ascorbate and aldarate metabolism (43)
- Chondroitin sulfate biosynthesis (42)
- Ether lipid metabolism (42)
- Heparan sulfate biosynthesis (42)
- p53 signaling pathway (42)
- Prion diseases (38)
- Pyrimidine metabolism (38)
- Glutathione metabolism (37)
- Asthma (36)
- Glycerolipid metabolism (35)
- Hedgehog signaling pathway (35)
- Linoleic acid metabolism (35)
- Tyrosine metabolism (35)
- B cell receptor signaling pathway (33)
- Glycosphingolipid biosynthesis - ganglio series (32)
- Glycosphingolipid biosynthesis - globo series (32)
- Progesterone-mediated oocyte maturation (30)
- Oocyte meiosis (29)
- Renal cell carcinoma (28)
- Renin-angiotensin system (28)
- Fc epsilon RI signaling pathway (27)
- Steroid biosynthesis (27)
- Biosynthesis of unsaturated fatty acids (26)
- Pathogenic Escherichia coli infection (26)
- Cytosolic DNA-sensing pathway (24)
- Insulin signaling pathway (24)
- Small cell lung cancer (24)
- Chronic myeloid leukemia (22)
- Riboflavin metabolism (22)
- Galactose metabolism (19)
- Glycosaminoglycan degradation (18)
- Nicotinate and nicotinamide metabolism (17)
- Primary bile acid biosynthesis (16)
- Ubiquitin mediated proteolysis (16)
- Protein export (14)
- alpha-Linolenic acid metabolism (14)
- Cyanoamino acid metabolism (13)
- Phosphatidylinositol signaling system (13)
- Selenoamino acid metabolism (13)
- Taurine and hypotaurine metabolism (13)
- VEGF signaling pathway (13)
- Amino sugar and nucleotide sugar metabolism (12)
- RIG-I-like receptor signaling pathway (12)
- Inositol phosphate metabolism (11)
- Phenylalanine metabolism (11)
- O-Mannosyl glycan biosynthesis (10)
- Acute myeloid leukemia (9)
- Glycolysis / Gluconeogenesis (9)
- C21-Steroid hormone metabolism (8)
- Caffeine metabolism (8)
- Citrate cycle (TCA cycle) (8)
- Glycine (8)
- Sulfur metabolism (8)
- serine and threonine metabolism (8)
- Propanoate metabolism (7)
- Tryptophan metabolism (7)
- beta-Alanine metabolism (7)
- Limonene and pinene degradation (6)
- Nitrogen metabolism (6)
- Base excision repair (5)
- NOD-like receptor signaling pathway (5)
- Valine (5)
- leucine and isoleucine degradation (5)
- Arginine and proline metabolism (4)
- Fatty acid elongation in mitochondria (4)
- Histidine metabolism (4)
- Maturity onset diabetes of the young (4)
- Pantothenate and CoA biosynthesis (4)
- Pyruvate metabolism (4)
- Terpenoid backbone biosynthesis (4)
- Cell cycle (3)
- Lysine degradation (3)
- Other glycan degradation (3)
- Butanoate metabolism (2)
- Fatty acid biosynthesis (2)
- Ubiquinone and other terpenoid-quinone biosynthesis (2)