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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

CTNNB1

PRKCG

CTNND1

BETA CATENIN

RHOH

BCAR1

CTNNA2

G PROTEIN ALPHA INHIBITOR 2

ALPHA 1 CATENIN

EPAC2

MMP2

PIK3R5

RAP1B

SDF1

MRCL3

PI 3 KINASE P85 ALPHA

ACTN2

ALPHA ACTININ

CLAUDIN 10

CLAUDIN 15

CLAUDIN18

CLDN19

JUNCTIONAL ADHESION MOLECULE 2

L AFADIN

OLIGODENDROCYTE SPECIFIC PROTEIN

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

PI 3 KINASE P55 GAMMA

PIK3CB

RAP1A

RHOGAP

SHC

SHP2

SIPA1

VAV1

VCAM1

ACTN3

CD11A

CD11B

CD18

CD90

CD99

CLAUDIN 2

CLAUDIN 5

CLAUDIN 7

CLAUDIN 9

CLDN16

CTNNA3

CXCR4

CYBB

EPAC1

FAK

G PROTEIN ALPHA INHIBITOR 1

GAMMA ACTIN

GRLF1

JUNCTIONAL ADHESION MOLECULE C

NORE1

NOX1

P38

PAXILLIN

PHOSPHOLIPASE C GAMMA 1

PI 3 KINASE P85 BETA

PIK3CA

PKC ALPHA

PYK2

RAC2

ROCK1

SAPK3

TXK

VASP

VAV2

VE CADHERIN

VINCULIN

Myc-DDK

TurboGFP

pCMV6-Entry

No

Yes

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

ES Cell Differentiation/IPS

Transcription Factors

Protein Kinase

Transmembrane

Protease

Secreted Protein

Ion Channels: Other

Phosphatase

Stem cell - Pluripotency

GPCR

Pathways in cancer

Metabolic pathways

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

MAPK signaling pathway

Pancreatic cancer

Prostate cancer

Focal adhesion

Ubiquitin mediated proteolysis

Melanoma

Regulation of actin cytoskeleton

Mismatch repair

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

p53 signaling pathway

mTOR signaling pathway

Glioma

Endocytosis

Thyroid cancer

Non-small cell lung cancer

Chronic myeloid leukemia

Neurotrophin signaling pathway

Type II diabetes mellitus

ErbB signaling pathway

Chemokine signaling pathway

Bladder cancer

Natural killer cell mediated cytotoxicity

Calcium signaling pathway

Renal cell carcinoma

Cytokine-cytokine receptor interaction

Tight junction

Progesterone-mediated oocyte maturation

Wnt signaling pathway

T cell receptor signaling pathway

Small cell lung cancer

Primary immunodeficiency

Neuroactive ligand-receptor interaction

Gap junction

Melanogenesis

GnRH signaling pathway

Vascular smooth muscle contraction

Homologous recombination

Long-term depression

Glycolysis / Gluconeogenesis

Acute myeloid leukemia

Adherens junction

Cell cycle

Olfactory transduction

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Apoptosis

VEGF signaling pathway

Leukocyte transendothelial migration

Huntington's disease

Maturity onset diabetes of the young

Long-term potentiation

Galactose metabolism

Jak-STAT signaling pathway

Axon guidance

Dorso-ventral axis formation

Fc gamma R-mediated phagocytosis

Phosphatidylinositol signaling system

Alzheimer's disease

Basal cell carcinoma

Notch signaling pathway

Toll-like receptor signaling pathway

Purine metabolism

Dilated cardiomyopathy

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Amyotrophic lateral sclerosis (ALS)

Inositol phosphate metabolism

Adipocytokine signaling pathway

Cell adhesion molecules (CAMs)

Oocyte meiosis

Hypertrophic cardiomyopathy (HCM)

Lysosome

Vibrio cholerae infection

Viral myocarditis

Epithelial cell signaling in Helicobacter pylori infection

ECM-receptor interaction

Pyrimidine metabolism

Taste transduction

Pathogenic Escherichia coli infection

Citrate cycle (TCA cycle)

Hematopoietic cell lineage

Parkinson's disease

Oxidative phosphorylation

PPAR signaling pathway

Spliceosome

Cardiac muscle contraction

TGF-beta signaling pathway

Nucleotide excision repair

Glycerophospholipid metabolism

NOD-like receptor signaling pathway

ABC transporters

Drug metabolism - cytochrome P450

RIG-I-like receptor signaling pathway

Metabolism of xenobiotics by cytochrome P450

Systemic lupus erythematosus

RNA degradation

Prion diseases

Glutathione metabolism

Complement and coagulation cascades

Retinol metabolism

Drug metabolism - other enzymes

Cytosolic DNA-sensing pathway

N-Glycan biosynthesis

Arachidonic acid metabolism

Lysine degradation

Ribosome

Arginine and proline metabolism

Base excision repair

Tyrosine metabolism

Antigen processing and presentation

Hedgehog signaling pathway

Pyruvate metabolism

Fatty acid metabolism

Glycerolipid metabolism

Sphingolipid metabolism

Cysteine and methionine metabolism

Autoimmune thyroid disease

Porphyrin and chlorophyll metabolism

Type I diabetes mellitus

Valine

DNA replication

Basal transcription factors

Tryptophan metabolism

Proteasome

RNA polymerase

Aminoacyl-tRNA biosynthesis

leucine and isoleucine degradation

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pentose and glucuronate interconversions

Phenylalanine metabolism

Propanoate metabolism

Histidine metabolism

Allograft rejection

Fructose and mannose metabolism

Graft-versus-host disease

Nitrogen metabolism

Selenoamino acid metabolism

Ether lipid metabolism

Glycine

Steroid biosynthesis

serine and threonine metabolism

SNARE interactions in vesicular transport

Alanine

Ascorbate and aldarate metabolism

Glycosaminoglycan degradation

Keratan sulfate biosynthesis

Pantothenate and CoA biosynthesis

aspartate and glutamate metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

One carbon pool by folate

Pentose phosphate pathway

Nicotinate and nicotinamide metabolism

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

Regulation of autophagy

Riboflavin metabolism

Biosynthesis of unsaturated fatty acids

Butanoate metabolism

Cyanoamino acid metabolism

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Protein export

beta-Alanine metabolism

Circadian rhythm - mammal

Glycosphingolipid biosynthesis - ganglio series

Other glycan degradation

Asthma

Taurine and hypotaurine metabolism

Limonene and pinene degradation

O-Glycan biosynthesis

Renin-angiotensin system

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Terpenoid backbone biosynthesis

Lysine biosynthesis

Thiamine metabolism

leucine and isoleucine biosynthesis

Fatty acid biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

Folate biosynthesis

Sulfur metabolism

Lipoic acid metabolism

Methane metabolism

Phenylalanine

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

C21-Steroid hormone metabolism

Vitamin B6 metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

1

Yes

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