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cDNA Clones

Mutant ORF Clones

Expression Plasmids

Human

P53

CDKN2A

CDKN1C

BUB1B

CDC25B

APC10

APC11

ARTEMIS

CYCLIN D3

RB1

SA2

CDK4

MDM2

P21

CDK1

CDKN1B

CYCLIN A1

DP2

MIZ1

P57 KIP2

PKMYT1

ANAPC13

APC4

APC7

BUB1

CDC14B

CDC25C

CDC27

CDC45L

CHK2

CYCLIN B3

CYCLIN E1

E2F5

GADD45A

MCM7

MYC

ORC1

ORC3L

ORC4L

ORC5L

P16INK4A

SECURIN

SKP2

SMAD3

14-3-3 ZETA

APC1

APC5

ATM

ATR

BUBR1

CDC14A

CDC25A

CDK2

CDK7

CHK1

CYCLIN B1

CYCLIN H

E2F2

E2F3

EP300

KAT3A / CBP

MCM3

MPS1

P107

P27 KIP 1

SEPARASE

SMC1

SMC1L2

SMC3

TGF BETA 1

TGF BETA 2

WEE1

Myc-DDK

TurboGFP

pCMV6-Entry

pCMV6-AC-Myc-DDK

Yes

No

TrueORF

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Stem cell - Pluripotency

Protein Kinase

Phosphatase

Embryonic stem cells

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

ES Cell Differentiation/IPS

Cancer stem cells

Induced pluripotent stem cells

Secreted Protein

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Protease

Transmembrane

Pathways in cancer

Metabolic pathways

Colorectal cancer

Insulin signaling pathway

Endometrial cancer

MAPK signaling pathway

Pancreatic cancer

Prostate cancer

Focal adhesion

Ubiquitin mediated proteolysis

Melanoma

Regulation of actin cytoskeleton

Mismatch repair

B cell receptor signaling pathway

Fc epsilon RI signaling pathway

p53 signaling pathway

mTOR signaling pathway

Glioma

Endocytosis

Thyroid cancer

Non-small cell lung cancer

Chronic myeloid leukemia

Neurotrophin signaling pathway

Type II diabetes mellitus

ErbB signaling pathway

Chemokine signaling pathway

Bladder cancer

Natural killer cell mediated cytotoxicity

Calcium signaling pathway

Renal cell carcinoma

Cytokine-cytokine receptor interaction

Tight junction

Progesterone-mediated oocyte maturation

Wnt signaling pathway

T cell receptor signaling pathway

Primary immunodeficiency

Small cell lung cancer

Neuroactive ligand-receptor interaction

Gap junction

Melanogenesis

Vascular smooth muscle contraction

GnRH signaling pathway

Homologous recombination

Long-term depression

Glycolysis / Gluconeogenesis

Acute myeloid leukemia

Adherens junction

Cell cycle

Olfactory transduction

Starch and sucrose metabolism

Amino sugar and nucleotide sugar metabolism

Apoptosis

VEGF signaling pathway

Leukocyte transendothelial migration

Huntington's disease

Maturity onset diabetes of the young

Galactose metabolism

Long-term potentiation

Jak-STAT signaling pathway

Axon guidance

Dorso-ventral axis formation

Fc gamma R-mediated phagocytosis

Phosphatidylinositol signaling system

Basal cell carcinoma

Notch signaling pathway

Alzheimer's disease

Toll-like receptor signaling pathway

Dilated cardiomyopathy

Purine metabolism

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Amyotrophic lateral sclerosis (ALS)

Inositol phosphate metabolism

Adipocytokine signaling pathway

Cell adhesion molecules (CAMs)

Oocyte meiosis

Hypertrophic cardiomyopathy (HCM)

Vibrio cholerae infection

Viral myocarditis

Lysosome

Epithelial cell signaling in Helicobacter pylori infection

Taste transduction

ECM-receptor interaction

Pyrimidine metabolism

Citrate cycle (TCA cycle)

Pathogenic Escherichia coli infection

Hematopoietic cell lineage

Parkinson's disease

Oxidative phosphorylation

PPAR signaling pathway

Spliceosome

TGF-beta signaling pathway

Cardiac muscle contraction

Nucleotide excision repair

Glycerophospholipid metabolism

NOD-like receptor signaling pathway

ABC transporters

Drug metabolism - cytochrome P450

RIG-I-like receptor signaling pathway

Metabolism of xenobiotics by cytochrome P450

Systemic lupus erythematosus

RNA degradation

Prion diseases

Glutathione metabolism

Retinol metabolism

Complement and coagulation cascades

Drug metabolism - other enzymes

Cytosolic DNA-sensing pathway

N-Glycan biosynthesis

Arachidonic acid metabolism

Arginine and proline metabolism

Lysine degradation

Ribosome

Base excision repair

Tyrosine metabolism

Antigen processing and presentation

Hedgehog signaling pathway

Pyruvate metabolism

Fatty acid metabolism

Glycerolipid metabolism

Sphingolipid metabolism

Cysteine and methionine metabolism

Autoimmune thyroid disease

Porphyrin and chlorophyll metabolism

Type I diabetes mellitus

Valine

DNA replication

Basal transcription factors

Tryptophan metabolism

RNA polymerase

Aminoacyl-tRNA biosynthesis

Proteasome

leucine and isoleucine degradation

Androgen and estrogen metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Pentose and glucuronate interconversions

Phenylalanine metabolism

Propanoate metabolism

Allograft rejection

Histidine metabolism

Fructose and mannose metabolism

Graft-versus-host disease

Nitrogen metabolism

Selenoamino acid metabolism

Ether lipid metabolism

Glycine

Steroid biosynthesis

serine and threonine metabolism

SNARE interactions in vesicular transport

Ascorbate and aldarate metabolism

Glycosaminoglycan degradation

Keratan sulfate biosynthesis

Alanine

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

One carbon pool by folate

aspartate and glutamate metabolism

Pantothenate and CoA biosynthesis

Pentose phosphate pathway

Nicotinate and nicotinamide metabolism

Chondroitin sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

Regulation of autophagy

Biosynthesis of unsaturated fatty acids

Butanoate metabolism

Cyanoamino acid metabolism

Riboflavin metabolism

Circadian rhythm - mammal

Heparan sulfate biosynthesis

Primary bile acid biosynthesis

Protein export

Asthma

Glycosphingolipid biosynthesis - ganglio series

Other glycan degradation

beta-Alanine metabolism

Taurine and hypotaurine metabolism

Limonene and pinene degradation

O-Glycan biosynthesis

alpha-Linolenic acid metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Renin-angiotensin system

Terpenoid backbone biosynthesis

Lysine biosynthesis

Thiamine metabolism

leucine and isoleucine biosynthesis

Fatty acid biosynthesis

Folate biosynthesis

O-Mannosyl glycan biosynthesis

Biotin metabolism

Sulfur metabolism

Lipoic acid metabolism

Methane metabolism

Phenylalanine

Synthesis and degradation of ketone bodies

tyrosine and tryptophan biosynthesis

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

C21-Steroid hormone metabolism

Vitamin B6 metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Neomycin

None

1

Yes

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