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cDNA Clones

Mutant ORF Clones

Expression Plasmids

Human

P53

EVI1

PIK3R5

MDM2

P21

PI 3 KINASE P85 ALPHA

SHC

ACTIVIN A RECEPTOR TYPE IC

SMAD3

A RAF

ACTIVIN A RECEPTOR TYPE IB

AKT2

AKT3

IKK BETA

NF-KB P65

P16INK4A

RUNX1

STAT5A

IKK GAMMA

PI 3 KINASE P55 GAMMA

PIK3CB

SHP2

AKT1

BCR

E2F3

ERK1

ERK2

NFKB1

P21 RAS

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

B RAF

BAD

BCL X

C ABL

CBL C

CDK6

E2F2

GAB2

GRB2

KRAS

P38

PI 3 KINASE CATALYTIC SUBUNIT ALPHA

PI 3 KINASE P85 BETA

SOS1

TGF BETA 1

TGF BETA 2

C-MYC

CBL

CBLB

CDK4

CRKL

CYCLIN D1

E2F1

HDAC1

HDAC2

IKB ALPHA

IKK ALPHA

MEK1

MEK2

NRAS

P27 KIP 1

PIK3CD

RAF1

RB

SMAD4

STAT5B

TGF BETA 3

TurboGFP

Myc-DDK

pCMV6-AC-GFP

pCMV6-Entry

No

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

ES Cell Differentiation/IPS

Stem cell - Pluripotency

Transmembrane

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Cancer stem cells

Secreted Protein

Phosphatase

Adult stem cells

Induced pluripotent stem cells

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Neuroactive ligand-receptor interaction

Cytokine-cytokine receptor interaction

Calcium signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Chemokine signaling pathway

Progesterone-mediated oocyte maturation

Jak-STAT signaling pathway

Wnt signaling pathway

Neurotrophin signaling pathway

Insulin signaling pathway

Axon guidance

Alzheimer's disease

Apoptosis

Endocytosis

Purine metabolism

T cell receptor signaling pathway

Ubiquitin mediated proteolysis

Vascular smooth muscle contraction

Natural killer cell mediated cytotoxicity

Cell cycle

Prostate cancer

ErbB signaling pathway

Adherens junction

GnRH signaling pathway

Oocyte meiosis

Dilated cardiomyopathy

Leukocyte transendothelial migration

Colorectal cancer

Toll-like receptor signaling pathway

Small cell lung cancer

Hematopoietic cell lineage

Type II diabetes mellitus

Pancreatic cancer

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Gap junction

p53 signaling pathway

Cell adhesion molecules (CAMs)

Hypertrophic cardiomyopathy (HCM)

Long-term potentiation

Melanogenesis

VEGF signaling pathway

Renal cell carcinoma

Melanoma

Tight junction

B cell receptor signaling pathway

Olfactory transduction

Fc gamma R-mediated phagocytosis

Huntington's disease

Chronic myeloid leukemia

ECM-receptor interaction

Long-term depression

Endometrial cancer

Glioma

Acute myeloid leukemia

Adipocytokine signaling pathway

Lysosome

NOD-like receptor signaling pathway

Phosphatidylinositol signaling system

Amyotrophic lateral sclerosis (ALS)

TGF-beta signaling pathway

Bladder cancer

Non-small cell lung cancer

Fc epsilon RI signaling pathway

PPAR signaling pathway

Complement and coagulation cascades

Viral myocarditis

Cardiac muscle contraction

mTOR signaling pathway

RIG-I-like receptor signaling pathway

ABC transporters

Basal cell carcinoma

Inositol phosphate metabolism

Epithelial cell signaling in Helicobacter pylori infection

Glycolysis / Gluconeogenesis

Pyrimidine metabolism

Taste transduction

Hedgehog signaling pathway

Drug metabolism - cytochrome P450

Glycerophospholipid metabolism

Thyroid cancer

Arachidonic acid metabolism

Metabolism of xenobiotics by cytochrome P450

Pathogenic Escherichia coli infection

Base excision repair

Cytosolic DNA-sensing pathway

Tyrosine metabolism

Parkinson's disease

Arginine and proline metabolism

Retinol metabolism

Glycerolipid metabolism

Drug metabolism - other enzymes

Valine

Primary immunodeficiency

Antigen processing and presentation

Lysine degradation

Fatty acid metabolism

Cysteine and methionine metabolism

Prion diseases

Notch signaling pathway

Nucleotide excision repair

Autoimmune thyroid disease

leucine and isoleucine degradation

Glutathione metabolism

Pyruvate metabolism

Systemic lupus erythematosus

Vibrio cholerae infection

Sphingolipid metabolism

Tryptophan metabolism

Type I diabetes mellitus

Starch and sucrose metabolism

Histidine metabolism

Homologous recombination

Fructose and mannose metabolism

Galactose metabolism

SNARE interactions in vesicular transport

Mismatch repair

Amino sugar and nucleotide sugar metabolism

Maturity onset diabetes of the young

Propanoate metabolism

Dorso-ventral axis formation

Proteasome

Nitrogen metabolism

Butanoate metabolism

Phenylalanine metabolism

Alanine

Aminoacyl-tRNA biosynthesis

aspartate and glutamate metabolism

Allograft rejection

Linoleic acid metabolism

Oxidative phosphorylation

Pentose phosphate pathway

Androgen and estrogen metabolism

Citrate cycle (TCA cycle)

Ether lipid metabolism

Renin-angiotensin system

DNA replication

Riboflavin metabolism

Selenoamino acid metabolism

Regulation of autophagy

Steroid biosynthesis

Graft-versus-host disease

Spliceosome

Non-homologous end-joining

Porphyrin and chlorophyll metabolism

Glycosaminoglycan degradation

beta-Alanine metabolism

Other glycan degradation

Circadian rhythm - mammal

Pantothenate and CoA biosynthesis

Glycine

serine and threonine metabolism

Primary bile acid biosynthesis

Ribosome

N-Glycan biosynthesis

leucine and isoleucine biosynthesis

Terpenoid backbone biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

C21-Steroid hormone metabolism

RNA degradation

Asthma

Ascorbate and aldarate metabolism

Folate biosynthesis

Limonene and pinene degradation

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Protein export

Fatty acid biosynthesis

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Glycosphingolipid biosynthesis - ganglio series

Glyoxylate and dicarboxylate metabolism

Thiamine metabolism

Biosynthesis of unsaturated fatty acids

Taurine and hypotaurine metabolism

Glycosphingolipid biosynthesis - globo series

Glycosphingolipid biosynthesis - lacto and neolacto series

Phenylalanine

tyrosine and tryptophan biosynthesis

Caffeine metabolism

Heparan sulfate biosynthesis

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid elongation in mitochondria

Sulfur metabolism

Biotin metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Methane metabolism

Chondroitin sulfate biosynthesis

RNA polymerase

Lysine biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

Neomycin

1

Yes

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