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Species
Target Symbol
- DISC1 (17)
- ALPHA DYSTROGLYCAN (13)
- NRG1 (11)
- VEGFA (11)
- FGFR1 (10)
- IGHG1 (10)
- MITF (10)
- PARD3 (10)
- BCAR1 (9)
- FAM122C (9)
- BHLHB9 (8)
- CACNA1C (8)
- CADHERIN LIKE 23 (8)
- IGLL1 (8)
- MCFD2 (8)
- OPA1 (8)
- TNIK (8)
- UBE2D3 (8)
- APBB2 (7)
- ASPARTATE BETA HYDROXYLASE (7)
- ATAXIN 3 (7)
- BIN1 (7)
- CAMK2G (7)
- HLA (7)
- MAX (7)
- NAT1 (7)
- RAD17 (7)
- SNRPN (7)
- TAU (7)
- ZBTB20 (7)
- ZNF268 (7)
- ACRV1 (6)
- AFF2 (6)
- APOL3 (6)
- ARMCX5 (6)
- C15ORF40 (6)
- CAMK2D (6)
- CAMKK2 (6)
- CPNE1 (6)
- DIAZEPAM BINDING INHIBITOR (6)
- DYSTROBREVIN ALPHA (6)
- HNF 4 ALPHA (6)
- MARK2 (6)
- MST1 (6)
- NDUFC1 (6)
- P38 (6)
- PTGER3 (6)
- RANTES (6)
- RDM1 (6)
- RPS6KA3 (6)
- SCOC (6)
- SSH3BP1 (6)
- STAU2 (6)
- TJAP1 (6)
- TRPT1 (6)
- VEPH1 (6)
- ZDHHC16 (6)
- ZNF135 (6)
- 5HT4 RECEPTOR (5)
- AREB6 (5)
- BDNF (5)
- BLCAP (5)
- CAMK2B (5)
- CASPASE 8 (5)
- CATHEPSIN B (5)
- CCRK (5)
- CD46 (5)
- CD89 (5)
- CHREBP (5)
- CKII ALPHA (5)
- CLATHRIN LIGHT CHAIN (5)
- CPEB2 (5)
- DMT1 (5)
- DPP10 (5)
- FAM104B (5)
- FCRLM1 (5)
- FOXP2 (5)
- GABPB2 (5)
- GPR64 (5)
- GSK3 BETA (5)
- HCK (5)
- HGF (5)
- IL1RAP (5)
- IRF5 (5)
- JNK1 (5)
- KCNQ5 (5)
- LIM KINASE 2 (5)
- MEPE (5)
- MIER1 (5)
- MPS1 (5)
- MYOSIN LIGHT CHAIN KINASE (5)
- NALP2 (5)
- NEU4 (5)
- P40 (5)
- PARP9 (5)
- PCDH11X (5)
- PTPRD (5)
- PYK2 (5)
- RIBONUCLEASE INHIBITOR (5)
- RIM1 (5)
Tags
Mutants
Families
- Druggable Genome (7663)
- Transmembrane (4468)
- Transcription Factors (1988)
- Secreted Protein (1262)
- Protein Kinase (968)
- Protease (515)
- ES Cell Differentiation/IPS (449)
- GPCR (369)
- Stem cell - Pluripotency (346)
- Phosphatase (223)
- Ion Channels: Other (141)
- Adult stem cells (107)
- Embryonic stem cells (86)
- Ion Channels: Potassium (86)
- Nuclear Hormone Receptor (82)
- Cancer stem cells (52)
- P450 (51)
- Induced pluripotent stem cells (49)
- Ion Channels: Cys-loop Receptors (46)
- Ion Channels: Transient receptor potential (34)
- Ion Channels: Glutamate Receptors (25)
- Stem cell relevant signaling - JAK/STAT signaling pathway (25)
- Ion Channels: Sodium (24)
- Stem cell relevant signaling - DSL/Notch pathway (23)
- Stem cell relevant signaling - Wnt Signaling pathway (23)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (22)
- Ion Channels: Calcium (19)
- Ion Channels: ATP Receptors (9)
- Ion Channels: Cyclic nucleotide gated (6)
Pathways
- Metabolic pathways (1109)
- Pathways in cancer (517)
- MAPK signaling pathway (430)
- Neuroactive ligand-receptor interaction (333)
- Cytokine-cytokine receptor interaction (314)
- Regulation of actin cytoskeleton (294)
- Focal adhesion (287)
- Chemokine signaling pathway (252)
- Neurotrophin signaling pathway (244)
- Endocytosis (243)
- Calcium signaling pathway (240)
- Wnt signaling pathway (233)
- Huntington's disease (205)
- Alzheimer's disease (203)
- Insulin signaling pathway (192)
- Tight junction (182)
- Ubiquitin mediated proteolysis (181)
- Axon guidance (178)
- ErbB signaling pathway (177)
- Cell adhesion molecules (CAMs) (175)
- Jak-STAT signaling pathway (175)
- Cell cycle (172)
- Natural killer cell mediated cytotoxicity (168)
- Progesterone-mediated oocyte maturation (167)
- Oocyte meiosis (164)
- T cell receptor signaling pathway (164)
- GnRH signaling pathway (160)
- Melanogenesis (159)
- Purine metabolism (158)
- Leukocyte transendothelial migration (155)
- Toll-like receptor signaling pathway (154)
- Vascular smooth muscle contraction (154)
- Prostate cancer (148)
- Colorectal cancer (137)
- Fc gamma R-mediated phagocytosis (137)
- Lysosome (135)
- Pancreatic cancer (135)
- Parkinson's disease (135)
- Apoptosis (133)
- Melanoma (132)
- Oxidative phosphorylation (131)
- Adherens junction (130)
- Spliceosome (128)
- Long-term potentiation (124)
- VEGF signaling pathway (124)
- Fc epsilon RI signaling pathway (119)
- Hematopoietic cell lineage (119)
- Chronic myeloid leukemia (118)
- Small cell lung cancer (118)
- Glioma (117)
- Gap junction (116)
- Renal cell carcinoma (116)
- Dilated cardiomyopathy (113)
- Pyrimidine metabolism (111)
- B cell receptor signaling pathway (109)
- TGF-beta signaling pathway (108)
- p53 signaling pathway (108)
- Viral myocarditis (107)
- Ribosome (105)
- Hypertrophic cardiomyopathy (HCM) (104)
- NOD-like receptor signaling pathway (104)
- Epithelial cell signaling in Helicobacter pylori infection (101)
- Acute myeloid leukemia (100)
- Antigen processing and presentation (99)
- Adipocytokine signaling pathway (98)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (96)
- ECM-receptor interaction (96)
- mTOR signaling pathway (96)
- Long-term depression (95)
- Non-small cell lung cancer (95)
- Systemic lupus erythematosus (95)
- RIG-I-like receptor signaling pathway (94)
- Endometrial cancer (91)
- PPAR signaling pathway (89)
- Complement and coagulation cascades (86)
- Amyotrophic lateral sclerosis (ALS) (83)
- Bladder cancer (82)
- Type II diabetes mellitus (81)
- Hedgehog signaling pathway (79)
- Phosphatidylinositol signaling system (77)
- Cardiac muscle contraction (76)
- Olfactory transduction (72)
- Basal cell carcinoma (71)
- Glycolysis / Gluconeogenesis (70)
- Drug metabolism - cytochrome P450 (67)
- Vibrio cholerae infection (67)
- Glycerophospholipid metabolism (64)
- Pathogenic Escherichia coli infection (64)
- Cytosolic DNA-sensing pathway (63)
- Metabolism of xenobiotics by cytochrome P450 (63)
- Type I diabetes mellitus (57)
- Graft-versus-host disease (56)
- Arachidonic acid metabolism (55)
- Autoimmune thyroid disease (55)
- Inositol phosphate metabolism (55)
- Valine (55)
- Notch signaling pathway (53)
- Prion diseases (53)
- Drug metabolism - other enzymes (52)
- Retinol metabolism (52)
- Lysine degradation (51)
- Starch and sucrose metabolism (50)
- Allograft rejection (49)
- Primary immunodeficiency (49)
- Sphingolipid metabolism (49)
- Glutathione metabolism (48)
- Glycerolipid metabolism (48)
- Amino sugar and nucleotide sugar metabolism (46)
- Proteasome (46)
- N-Glycan biosynthesis (45)
- Nucleotide excision repair (45)
- Pyruvate metabolism (45)
- Arginine and proline metabolism (44)
- Taste transduction (44)
- Fatty acid metabolism (43)
- SNARE interactions in vesicular transport (43)
- leucine and isoleucine degradation (43)
- RNA degradation (42)
- Thyroid cancer (42)
- Tyrosine metabolism (42)
- ABC transporters (41)
- Androgen and estrogen metabolism (41)
- Cysteine and methionine metabolism (41)
- Tryptophan metabolism (41)
- Asthma (39)
- Ether lipid metabolism (39)
- Fructose and mannose metabolism (39)
- Propanoate metabolism (39)
- Alanine (37)
- Maturity onset diabetes of the young (37)
- aspartate and glutamate metabolism (37)
- DNA replication (36)
- Aminoacyl-tRNA biosynthesis (35)
- Glycine (35)
- serine and threonine metabolism (35)
- Base excision repair (33)
- Butanoate metabolism (33)
- Regulation of autophagy (32)
- Basal transcription factors (31)
- Pentose phosphate pathway (31)
- Porphyrin and chlorophyll metabolism (31)
- Galactose metabolism (30)
- Citrate cycle (TCA cycle) (29)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (28)
- Homologous recombination (28)
- Mismatch repair (28)
- Nicotinate and nicotinamide metabolism (27)
- O-Glycan biosynthesis (27)
- Glycosaminoglycan degradation (26)
- RNA polymerase (26)
- Dorso-ventral axis formation (25)
- Histidine metabolism (25)
- Linoleic acid metabolism (25)
- Selenoamino acid metabolism (25)
- beta-Alanine metabolism (25)
- Biosynthesis of unsaturated fatty acids (23)
- Riboflavin metabolism (23)
- Glycosphingolipid biosynthesis - lacto and neolacto series (22)
- Nitrogen metabolism (22)
- Phenylalanine metabolism (22)
- Heparan sulfate biosynthesis (21)
- Other glycan degradation (21)
- Renin-angiotensin system (21)
- Ascorbate and aldarate metabolism (20)
- Primary bile acid biosynthesis (19)
- alpha-Linolenic acid metabolism (18)
- Chondroitin sulfate biosynthesis (17)
- Pentose and glucuronate interconversions (17)
- Sulfur metabolism (17)
- Keratan sulfate biosynthesis (16)
- One carbon pool by folate (16)
- Terpenoid backbone biosynthesis (16)
- Non-homologous end-joining (15)
- Pantothenate and CoA biosynthesis (15)
- Steroid biosynthesis (15)
- Glycosphingolipid biosynthesis - ganglio series (14)
- Glycosphingolipid biosynthesis - globo series (14)
- leucine and isoleucine biosynthesis (14)
- Circadian rhythm - mammal (13)
- Glyoxylate and dicarboxylate metabolism (13)
- C21-Steroid hormone metabolism (12)
- Caffeine metabolism (12)
- Limonene and pinene degradation (12)
- Protein export (12)
- Taurine and hypotaurine metabolism (12)
- Cyanoamino acid metabolism (11)
- Folate biosynthesis (9)
- Methane metabolism (9)
- Synthesis and degradation of ketone bodies (9)
- Thiamine metabolism (9)
- Fatty acid biosynthesis (8)
- Phenylalanine (6)
- Ubiquinone and other terpenoid-quinone biosynthesis (6)
- Vitamin B6 metabolism (6)
- tyrosine and tryptophan biosynthesis (6)
- Fatty acid elongation in mitochondria (5)
- D-Glutamine and D-glutamate metabolism (4)
- Lipoic acid metabolism (3)
- O-Mannosyl glycan biosynthesis (3)
- Biotin metabolism (2)
- Lysine biosynthesis (2)
- D-Arginine and D-ornithine metabolism (1)
