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Target Symbol
- DISC1 (15)
- IGHG1 (10)
- MITF (10)
- PARD3 (10)
- FAM122C (9)
- BCAR1 (8)
- HLA (8)
- ALPHA DYSTROGLYCAN (7)
- ATXN3 (7)
- CDH23 (7)
- NAT1 (7)
- NRG1 (7)
- SNRPN (7)
- TNIK (7)
- ZBTB20 (7)
- ACRV1 (6)
- APBB2 (6)
- ARMCX5 (6)
- C15ORF40 (6)
- DYSTROBREVIN ALPHA (6)
- IGLL1 (6)
- MARK2 (6)
- MCFD2 (6)
- NDUFC1 (6)
- RDM1 (6)
- SCOC (6)
- TAU (6)
- TJAP1 (6)
- TRPT1 (6)
- UBE2D3 (6)
- VEGFA (6)
- VEPH1 (6)
- ZNF135 (6)
- ZNF268 (6)
- ABI1 (5)
- AFF2 (5)
- APOL3 (5)
- BLCAP (5)
- CAMK2D (5)
- CPNE1 (5)
- DAG1 (5)
- DBI (5)
- FAM104B (5)
- FGFR1 (5)
- HNF 4 ALPHA (5)
- IRF5 (5)
- MEPE (5)
- MST1 (5)
- NEU4 (5)
- PCDH11X (5)
- RANTES (5)
- RIM1 (5)
- SEC23B (5)
- SFTPA1 (5)
- SH2B1 (5)
- SHMT2 (5)
- SYNRG (5)
- TJP2 (5)
- ADGRG2 (4)
- AMCASE (4)
- ASPH (4)
- BAX (4)
- BDNF (4)
- BEX2 (4)
- CACNA1C (4)
- CAMTA2 (4)
- CARD8 (4)
- CD44 (4)
- CDK1 (4)
- CDK2 (4)
- CDK4 (4)
- CLCN2 (4)
- COPS7A (4)
- CPEB2 (4)
- DACH1 (4)
- DPP10 (4)
- EWSR1 (4)
- FCRLA (4)
- FGF8 (4)
- FGFR4 (4)
- FXYD6 (4)
- GEMIN 1 (4)
- HCK (4)
- HDAC8 (4)
- HGF (4)
- HOPX (4)
- KCNQ5 (4)
- KIAA0040 (4)
- KIAA0319 (4)
- KLHL13 (4)
- KLHL7 (4)
- LYRM4 (4)
- M-CSF (4)
- MAGEA2 (4)
- MASTL (4)
- MAX (4)
- MIB2 (4)
- MIER1 (4)
- MLH1 (4)
- MTHFSD (4)
Mutants
Families
- Druggable Genome (4641)
- Transmembrane (2755)
- Transcription Factors (1281)
- Secreted Protein (796)
- Protein Kinase (476)
- Protease (294)
- ES Cell Differentiation/IPS (273)
- Stem cell - Pluripotency (236)
- GPCR (157)
- Phosphatase (116)
- Ion Channels: Other (82)
- Adult stem cells (67)
- Embryonic stem cells (60)
- Nuclear Hormone Receptor (45)
- Ion Channels: Potassium (39)
- Ion Channels: Cys-loop Receptors (34)
- Induced pluripotent stem cells (33)
- Cancer stem cells (32)
- P450 (19)
- Stem cell relevant signaling - DSL/Notch pathway (16)
- Stem cell relevant signaling - JAK/STAT signaling pathway (16)
- Stem cell relevant signaling - Wnt Signaling pathway (16)
- Ion Channels: Glutamate Receptors (14)
- Ion Channels: Transient receptor potential (14)
- Ion Channels: Calcium (13)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (13)
- Ion Channels: Sodium (12)
- Ion Channels: ATP Receptors (4)
- Ion Channels: Cyclic nucleotide gated (3)
Pathways
- Metabolic pathways (718)
- Pathways in cancer (281)
- MAPK signaling pathway (246)
- Cytokine-cytokine receptor interaction (184)
- Neuroactive ligand-receptor interaction (161)
- Huntington's disease (157)
- Endocytosis (153)
- Regulation of actin cytoskeleton (153)
- Focal adhesion (145)
- Alzheimer's disease (144)
- Chemokine signaling pathway (143)
- Neurotrophin signaling pathway (133)
- Tight junction (126)
- Wnt signaling pathway (124)
- Ubiquitin mediated proteolysis (122)
- Cell adhesion molecules (CAMs) (117)
- Calcium signaling pathway (108)
- Parkinson's disease (107)
- Insulin signaling pathway (106)
- Jak-STAT signaling pathway (106)
- Purine metabolism (105)
- Cell cycle (104)
- Oxidative phosphorylation (104)
- Natural killer cell mediated cytotoxicity (102)
- Spliceosome (102)
- Toll-like receptor signaling pathway (95)
- Melanogenesis (94)
- Lysosome (92)
- Oocyte meiosis (92)
- Leukocyte transendothelial migration (89)
- Progesterone-mediated oocyte maturation (89)
- Apoptosis (86)
- ErbB signaling pathway (85)
- Ribosome (85)
- Antigen processing and presentation (84)
- GnRH signaling pathway (84)
- Melanoma (84)
- Viral myocarditis (84)
- Axon guidance (82)
- T cell receptor signaling pathway (80)
- Vascular smooth muscle contraction (79)
- Prostate cancer (78)
- Hematopoietic cell lineage (76)
- Pancreatic cancer (75)
- p53 signaling pathway (75)
- Adherens junction (74)
- Pyrimidine metabolism (74)
- Colorectal cancer (71)
- Long-term potentiation (71)
- Systemic lupus erythematosus (70)
- Fc gamma R-mediated phagocytosis (67)
- Glioma (66)
- Chronic myeloid leukemia (64)
- Renal cell carcinoma (64)
- Fc epsilon RI signaling pathway (63)
- Small cell lung cancer (63)
- Gap junction (61)
- Dilated cardiomyopathy (60)
- NOD-like receptor signaling pathway (59)
- VEGF signaling pathway (59)
- TGF-beta signaling pathway (58)
- Amyotrophic lateral sclerosis (ALS) (56)
- RIG-I-like receptor signaling pathway (56)
- B cell receptor signaling pathway (55)
- Cardiac muscle contraction (55)
- Hypertrophic cardiomyopathy (HCM) (55)
- Non-small cell lung cancer (55)
- Epithelial cell signaling in Helicobacter pylori infection (54)
- mTOR signaling pathway (54)
- Glycolysis / Gluconeogenesis (53)
- Acute myeloid leukemia (52)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (51)
- Type I diabetes mellitus (50)
- Endometrial cancer (49)
- Graft-versus-host disease (49)
- ECM-receptor interaction (48)
- Long-term depression (47)
- Cytosolic DNA-sensing pathway (46)
- Adipocytokine signaling pathway (45)
- Autoimmune thyroid disease (45)
- Bladder cancer (45)
- Pathogenic Escherichia coli infection (45)
- Hedgehog signaling pathway (44)
- PPAR signaling pathway (44)
- Vibrio cholerae infection (44)
- Allograft rejection (43)
- Olfactory transduction (43)
- Proteasome (42)
- Type II diabetes mellitus (42)
- Valine (42)
- Complement and coagulation cascades (41)
- Glycerophospholipid metabolism (40)
- Basal cell carcinoma (38)
- Phosphatidylinositol signaling system (38)
- Nucleotide excision repair (37)
- Pyruvate metabolism (36)
- Arachidonic acid metabolism (35)
- Drug metabolism - cytochrome P450 (35)
- Metabolism of xenobiotics by cytochrome P450 (35)
- Amino sugar and nucleotide sugar metabolism (33)
- Asthma (33)
- Lysine degradation (33)
- Prion diseases (33)
- Primary immunodeficiency (32)
- Sphingolipid metabolism (32)
- Starch and sucrose metabolism (32)
- leucine and isoleucine degradation (32)
- Drug metabolism - other enzymes (31)
- Glutathione metabolism (31)
- RNA degradation (31)
- Aminoacyl-tRNA biosynthesis (30)
- N-Glycan biosynthesis (30)
- Propanoate metabolism (30)
- SNARE interactions in vesicular transport (30)
- Taste transduction (30)
- DNA replication (29)
- Maturity onset diabetes of the young (29)
- Notch signaling pathway (29)
- ABC transporters (28)
- Tryptophan metabolism (28)
- Cysteine and methionine metabolism (27)
- Thyroid cancer (27)
- Fructose and mannose metabolism (26)
- Glycerolipid metabolism (26)
- Inositol phosphate metabolism (26)
- Pentose phosphate pathway (26)
- Retinol metabolism (26)
- Tyrosine metabolism (26)
- Base excision repair (25)
- Butanoate metabolism (25)
- Ether lipid metabolism (25)
- Androgen and estrogen metabolism (24)
- Galactose metabolism (24)
- Arginine and proline metabolism (23)
- Glycine (23)
- Regulation of autophagy (23)
- serine and threonine metabolism (23)
- Alanine (22)
- Fatty acid metabolism (22)
- Mismatch repair (22)
- aspartate and glutamate metabolism (22)
- Basal transcription factors (21)
- Citrate cycle (TCA cycle) (21)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (21)
- Nicotinate and nicotinamide metabolism (20)
- beta-Alanine metabolism (19)
- Histidine metabolism (18)
- Linoleic acid metabolism (18)
- Porphyrin and chlorophyll metabolism (18)
- Nitrogen metabolism (17)
- Other glycan degradation (17)
- RNA polymerase (17)
- Selenoamino acid metabolism (17)
- Homologous recombination (16)
- Biosynthesis of unsaturated fatty acids (15)
- O-Glycan biosynthesis (14)
- Steroid biosynthesis (14)
- Glycosaminoglycan degradation (13)
- Dorso-ventral axis formation (12)
- Non-homologous end-joining (12)
- Phenylalanine metabolism (12)
- Protein export (12)
- Riboflavin metabolism (12)
- Terpenoid backbone biosynthesis (12)
- alpha-Linolenic acid metabolism (12)
- Ascorbate and aldarate metabolism (11)
- One carbon pool by folate (11)
- leucine and isoleucine biosynthesis (11)
- Cyanoamino acid metabolism (10)
- Glycosphingolipid biosynthesis - lacto and neolacto series (10)
- Heparan sulfate biosynthesis (10)
- Pantothenate and CoA biosynthesis (10)
- Sulfur metabolism (10)
- Circadian rhythm - mammal (9)
- Glycosphingolipid biosynthesis - globo series (9)
- Keratan sulfate biosynthesis (9)
- Methane metabolism (9)
- Pentose and glucuronate interconversions (9)
- Caffeine metabolism (8)
- Glycosphingolipid biosynthesis - ganglio series (8)
- Glyoxylate and dicarboxylate metabolism (8)
- Synthesis and degradation of ketone bodies (8)
- Taurine and hypotaurine metabolism (8)
- Limonene and pinene degradation (7)
- Primary bile acid biosynthesis (7)
- Renin-angiotensin system (7)
- Folate biosynthesis (6)
- C21-Steroid hormone metabolism (5)
- Chondroitin sulfate biosynthesis (5)
- Fatty acid elongation in mitochondria (5)
- Vitamin B6 metabolism (5)
- Fatty acid biosynthesis (4)
- Thiamine metabolism (4)
- Lipoic acid metabolism (3)
- Ubiquinone and other terpenoid-quinone biosynthesis (3)
- Lysine biosynthesis (2)
- Phenylalanine (2)
- tyrosine and tryptophan biosynthesis (2)
- Biotin metabolism (1)
- D-Arginine and D-ornithine metabolism (1)
- D-Glutamine and D-glutamate metabolism (1)
- O-Mannosyl glycan biosynthesis (1)