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cDNA Clones

Expression Plasmids

Mutant ORF Clones

Human

P53

EGFR

VEGFA

KRAS

NRAS

P21 RAS

B RAF

P16INK4A

FGFR3

HER2

P21

ERK1

MDM2

MEK1

MSK1

RAF1

THYMIDINE PHOSPHORYLASE

CDK4

ERK2

RASSF1

E2F3

PLGF

A RAF

DAP KINASE 1

MEK2

MMP2

C-MYC

CYCLIN D1

DAP KINASE 2

E2F1

E2F2

IL8

MMP1

MMP9

RB

THROMBOSPONDIN 1

VEGFB

VEGFC

VEGFD

ZIP KINASE

E CADHERIN

EGF

Myc-DDK

Tag Free

TurboGFP

DDK-His

pCMV6-Entry

pCMV6-AC-Myc-DDK

pCMV6-AC-GFP

pCMV6-XL5

pCMV6-XL4

pCMV6-XL5-DDK-His

pCMV6-AC

pCMV6-XL6

PCMV6-Neo

No

Yes

TrueORF

TrueClone

TrueORF Gold, TrueORF

Druggable Genome

Transcription Factors

Protein Kinase

Stem cell - Pluripotency

Secreted Protein

Transmembrane

ES Cell Differentiation/IPS

Stem cell relevant signaling - JAK/STAT signaling pathway

Adult stem cells

Cancer stem cells

Protease

Stem cell relevant signaling - Wnt Signaling pathway

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Focal adhesion

Neurotrophin signaling pathway

Chemokine signaling pathway

Wnt signaling pathway

Endocytosis

Calcium signaling pathway

Huntington's disease

Prostate cancer

Insulin signaling pathway

Alzheimer's disease

Jak-STAT signaling pathway

Cell cycle

Natural killer cell mediated cytotoxicity

Purine metabolism

Axon guidance

Colorectal cancer

Olfactory transduction

Ubiquitin mediated proteolysis

Tight junction

ErbB signaling pathway

Melanoma

T cell receptor signaling pathway

Pancreatic cancer

Apoptosis

Progesterone-mediated oocyte maturation

Cell adhesion molecules (CAMs)

Melanogenesis

Oocyte meiosis

GnRH signaling pathway

Leukocyte transendothelial migration

Glioma

Chronic myeloid leukemia

Toll-like receptor signaling pathway

Small cell lung cancer

Vascular smooth muscle contraction

Endometrial cancer

Lysosome

Non-small cell lung cancer

Fc gamma R-mediated phagocytosis

Gap junction

p53 signaling pathway

Adherens junction

Hematopoietic cell lineage

Spliceosome

VEGF signaling pathway

Renal cell carcinoma

Parkinson's disease

Systemic lupus erythematosus

B cell receptor signaling pathway

Bladder cancer

Fc epsilon RI signaling pathway

Dilated cardiomyopathy

Oxidative phosphorylation

Long-term potentiation

Pyrimidine metabolism

Acute myeloid leukemia

Amyotrophic lateral sclerosis (ALS)

TGF-beta signaling pathway

Antigen processing and presentation

Hypertrophic cardiomyopathy (HCM)

Long-term depression

Basal cell carcinoma

Thyroid cancer

Adipocytokine signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

NOD-like receptor signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Complement and coagulation cascades

Ribosome

PPAR signaling pathway

Viral myocarditis

ECM-receptor interaction

RIG-I-like receptor signaling pathway

mTOR signaling pathway

Cardiac muscle contraction

Glycolysis / Gluconeogenesis

Phosphatidylinositol signaling system

Pathogenic Escherichia coli infection

Type II diabetes mellitus

Glycerophospholipid metabolism

Drug metabolism - cytochrome P450

Vibrio cholerae infection

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Metabolism of xenobiotics by cytochrome P450

Arginine and proline metabolism

Valine

Inositol phosphate metabolism

Glutathione metabolism

Arachidonic acid metabolism

Autoimmune thyroid disease

RNA degradation

Retinol metabolism

Type I diabetes mellitus

Notch signaling pathway

Graft-versus-host disease

Taste transduction

Tyrosine metabolism

Fatty acid metabolism

N-Glycan biosynthesis

leucine and isoleucine degradation

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Proteasome

Pyruvate metabolism

Glycerolipid metabolism

Primary immunodeficiency

Prion diseases

Nucleotide excision repair

Sphingolipid metabolism

Starch and sucrose metabolism

Lysine degradation

Allograft rejection

Cysteine and methionine metabolism

Alanine

aspartate and glutamate metabolism

ABC transporters

Tryptophan metabolism

Base excision repair

SNARE interactions in vesicular transport

Dorso-ventral axis formation

Fructose and mannose metabolism

Androgen and estrogen metabolism

Ether lipid metabolism

Maturity onset diabetes of the young

Citrate cycle (TCA cycle)

DNA replication

Propanoate metabolism

Porphyrin and chlorophyll metabolism

Aminoacyl-tRNA biosynthesis

Butanoate metabolism

Regulation of autophagy

Homologous recombination

Pentose phosphate pathway

Asthma

Galactose metabolism

Glycine

serine and threonine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Nicotinate and nicotinamide metabolism

Selenoamino acid metabolism

Basal transcription factors

Histidine metabolism

RNA polymerase

O-Glycan biosynthesis

Glycosaminoglycan degradation

Linoleic acid metabolism

Mismatch repair

Nitrogen metabolism

Phenylalanine metabolism

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

beta-Alanine metabolism

Heparan sulfate biosynthesis

Biosynthesis of unsaturated fatty acids

Renin-angiotensin system

Riboflavin metabolism

Chondroitin sulfate biosynthesis

Sulfur metabolism

Keratan sulfate biosynthesis

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

Non-homologous end-joining

Other glycan degradation

Steroid biosynthesis

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - globo series

Pantothenate and CoA biosynthesis

Glyoxylate and dicarboxylate metabolism

One carbon pool by folate

Circadian rhythm - mammal

alpha-Linolenic acid metabolism

Terpenoid backbone biosynthesis

Glycosphingolipid biosynthesis - ganglio series

C21-Steroid hormone metabolism

Limonene and pinene degradation

leucine and isoleucine biosynthesis

Taurine and hypotaurine metabolism

Folate biosynthesis

Cyanoamino acid metabolism

Synthesis and degradation of ketone bodies

Fatty acid elongation in mitochondria

Caffeine metabolism

Protein export

Thiamine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Fatty acid biosynthesis

Methane metabolism

Phenylalanine

tyrosine and tryptophan biosynthesis

Vitamin B6 metabolism

Lipoic acid metabolism

D-Glutamine and D-glutamate metabolism

Lysine biosynthesis

Biotin metabolism

O-Mannosyl glycan biosynthesis

D-Arginine and D-ornithine metabolism

Neomycin

None

1

Yes

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