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BRAF mutant(V600D), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA
| Mutation | V600D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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BRAF mutant(V600R), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA
| Mutation | V600R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRAF mutant(V600M), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA
| Mutation | V600M |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
FGFR4 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens fibroblast growth factor receptor 4, transcript variant 1, Signal peptide (1-21) plus EC domain (22-369)
| Type | Human Tagged ORF Clone |
| Tag | DDK-His |
| Vector | pCMV6-XL5-DDK-His |
- TrueORF®
BRAF Mutant (K601E), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA
| Mutation | K601E |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EGFR Mutant (G719A), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA
| Mutation | G719A |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EGFR Mutant (L747_E749del), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA
| Mutation | L747_E749del |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HRAS mutant (Q61L), Myc-DDK-tagged ORF clone of Homo sapiens v-Ha-ras Harvey rat sarcoma viral oncogene homolog (HRAS), transcript variant 1 as transfection-ready DNA
| Mutation | Q61L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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Species
Target Symbol
- EGFR (27)
- KRAS (20)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (13)
- NRAS (12)
- B RAF (11)
- FGFR1 (9)
- P21 RAS (9)
- FGF1 (6)
- FGFR2 (6)
- FGFR3 (6)
- BAIAP2 (5)
- CD14 (4)
- CD51 (4)
- FGF8 (4)
- FGFR4 (4)
- INSULIN (4)
- LIM KINASE 2 (4)
- MEK1 (4)
- PI 3 KINASE P85 ALPHA (4)
- SHC (4)
- APC (3)
- BCAR1 (3)
- CDC42 (3)
- CYFIP2 (3)
- ENAH (3)
- ERK2 (3)
- FGF5 (3)
- GIT1 (3)
- ITGA7 (3)
- MYOSIN LIGHT CHAIN KINASE (3)
- PPP1A (3)
- SCIN (3)
- SSH2 (3)
- WAVE 1 (3)
- ABI2 (2)
- ALPHA ACTININ (2)
- BDKRB1 (2)
- BDKRB2 (2)
- CD49B (2)
- CHRM2 (2)
- COFILIN 2 (2)
- CYFIP1 (2)
- ERK1 (2)
- FAK (2)
- FGF12 (2)
- FGF14 (2)
- FGF16 (2)
- G PROTEIN ALPHA 13 (2)
- GAMMA ACTIN (2)
- GELSOLIN (2)
- INTEGRIN ALPHA 1 (2)
- INTEGRIN BETA 1 (2)
- INTEGRIN BETA 5 (2)
- INTEGRIN BETA 7 (2)
- IQGAP3 (2)
- LARG (2)
- MRAS (2)
- MYH14 (2)
- MYL12B (2)
- MYL9 (2)
- MYLK3 (2)
- P21 ARC (2)
- P38 (2)
- PAK1 (2)
- PAK2 (2)
- PAK3 (2)
- PAK4 (2)
- PAK5 (2)
- PAK6 (2)
- PAXILLIN (2)
- PDGF RECEPTOR ALPHA (2)
- PDGF RECEPTOR BETA (2)
- PI 3 KINASE P85 BETA (2)
- PIP5KI GAMMA (2)
- PROFILIN 2 (2)
- PROTEIN PHOSPHATASE 1 BETA (2)
- RAC1 (2)
- RAC2 (2)
- RAF1 (2)
- RHOA (2)
- RRAS2 (2)
- SCDGFB (2)
- SLINGSHOT HOMOLOG 1 (2)
- SOS1 (2)
- SOS2 (2)
- VINCULIN (2)
- A RAF (1)
- ACTN2 (1)
- ALPHA ACTININ 4 (1)
- ARHGEF1 (1)
- ARHGEF4 (1)
- ARHGEF6 (1)
- ARHGEF7 (1)
- ARPC1A (1)
- ARPC1B (1)
- ARPC2 (1)
- ARPC4 (1)
- BETA ACTIN (1)
- C3ORF10 (1)
- CD11A (1)
Families
- Druggable Genome (351)
- Protein Kinase (110)
- Transmembrane (100)
- Secreted Protein (77)
- ES Cell Differentiation/IPS (65)
- Adult stem cells (37)
- Cancer stem cells (27)
- Stem cell relevant signaling - JAK/STAT signaling pathway (27)
- Phosphatase (11)
- Embryonic stem cells (10)
- GPCR (10)
- Stem cell - Pluripotency (9)
- Transcription Factors (4)
- Induced pluripotent stem cells (2)
- Protease (1)
- Stem cell relevant signaling - Wnt Signaling pathway (1)
