Granzyme B (GZMB) (NM_004131) Human Recombinant Protein

CAT#: TP762707

Purified recombinant protein of Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB), 21Ile-End, with N-terminal His tag, expressed in E.coli, 50ug



Need it in bulk or customized?
Get a free quote

CNY 2,480.00


货期*
现货

规格
    • 50 ug

Product images

经常一起买 (1)
GZMB mouse monoclonal antibody,clone OTI4E6
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding the region (21Ile-End) of GZMB
Tag N-His
Predicted MW 27.8 kDa
Concentration >0.05 ug/ul as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 25mM Tris, 150mM NaCl, 10% glycerol, pH8.0, 1% SKL
Storage Store at -80°C after receiving vials.
Stability Stable for at least 1 year from receipt of products under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_004122
Locus ID 3002
UniProt ID P10144, Q67BC3
Refseq Size 941
Cytogenetics 14q12
Refseq ORF 741
Synonyms C11; CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT
Summary This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]
Protein Families Druggable Genome, Protease
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Graft-versus-host disease, Natural killer cell mediated cytotoxicity, Type I diabetes mellitus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Customer Reviews 
Loading...