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TCF4 (NM_003199) Human Recombinant Protein
CAT＃: TP760702
Purified recombinant protein of Human transcription factor 4 (TCF4), transcript variant 2, with N-terminal HIS tag, expressed in E.Coli, 50ug
View other "TCF4" proteins (8)
|
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CNY 2,040.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length TCF4
|
| Tag | N-His |
| Predicted MW | 71.1 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_003190 |
| Locus ID | 6925 |
| UniProt ID | P15884, B3KVA4, A0A024R2C0 |
| Refseq Size | 2500 |
| Cytogenetics | 18q21.2 |
| Refseq ORF | 2001 |
| Synonyms | bHLHb19; CDG2T; E2-2; FECD3; ITF-2; ITF2; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4 |
| Summary | This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016] |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
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Mechanism of Wnt signaling induced down regulation of mrhl long non-coding RNA in mouse spermatogonial cells
,null,
Nucleic Acids Research
,PubMed ID 26446991
[TCF4]
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Other Versions
| SKU | Description | Size | Price |
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| LC401106 | TCF4 HEK293T cell transient overexpression lysate (as WB positive control) |
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| LC421261 | TCF4 HEK293T cell transient overexpression lysate (as WB positive control) |
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| LY401106 | Transient overexpression lysate of transcription factor 4 (TCF4), transcript variant 2 |
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| LY421261 | Transient overexpression lysate of transcription factor 4 (TCF4), transcript variant 1 |
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| PH317718 | TCF4 MS Standard C13 and N15-labeled recombinant protein (NP_003190) |
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|
| PH324345 | TCF4 MS Standard C13 and N15-labeled recombinant protein (NP_001077431) |
CNY 19,520.00 |
|
| TP317718 | Recombinant protein of human transcription factor 4 (TCF4), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP324345 | Recombinant protein of human transcription factor 4 (TCF4), transcript variant 1, 20 µg |
CNY 2,900.00 |
